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TTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescence

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  DOI: 10.1016/j.celrep.2026.117703
  
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sciencedirect.com/science/article/pii/S2211124726007813
Apr 2026
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Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex

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1. scibot 02 Apr 2026
  
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  DOI: 10.1126/sciadv.adx8715
  
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science.org/doi/10.1126/sciadv.adx8715
Mar 2026
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Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex

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1. scibot 24 Mar 2026
  
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  DOI: 10.1126/sciadv.adx8715
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13004025/
Feb 2026
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1-s2.0-S2589004226004311-main-html.html

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.115056
  
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54.241.53.176/ec848ac32c78cddfb23f9dab7afd5557beac8c82/1-s2.0-S2589004226004311-main-html.html
Oct 2025
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The E3 ubiquitin ligase Trip12 semi-selectively attenuates Wnt signaling

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1. scibot 16 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113575
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519312/
Sep 2025
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PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113408
  
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sciencedirect.com/science/article/pii/S2589004225016694
Feb 2025
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

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  DOI: 10.1016/j.cell.2025.01.027
  
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sciencedirect.com/science/article/pii/S0092867425000960
May 2024
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Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists

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1. scibot 01 May 2024
  
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  DOI: 10.1101/2024.04.19.590338
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
Apr 2024
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A mechanism linking p53-mediated ferroptosis and NCOA4-mediated ferritinophagy in melatonin-related improvement of diabetic brain injury

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1. scibot 13 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109511
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10987905/
Feb 2024
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TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport

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1. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.ijbiomac.2024.130055
  
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sciencedirect.com/science/article/pii/S0141813024008584
Dec 2023
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Lysosomal dynamics regulate mammalian cortical neurogenesis

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1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.devcel.2023.11.021
  
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sciencedirect.com/science/article/pii/S1534580723006196
Sep 2023
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Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.molcel.2023.08.032
  
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sciencedirect.com/science/article/pii/S1097276523006950
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TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

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1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113070
  
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sciencedirect.com/science/article/pii/S2211124723010811
Jun 2023
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ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.chembiol.2023.05.010
  
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sciencedirect.com/science/article/pii/S2451945623001538
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An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

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1. scibot 16 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.018
  
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sciencedirect.com/science/article/pii/S109727652300374X
Mar 2023
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TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

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1. scibot 22 Mar 2023
  
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  DOI: 10.1016/j.jbc.2023.104621
  
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sciencedirect.com/science/article/pii/S0021925823002636
Jan 2023
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Targeting VPS41 induces methuosis and inhibits autophagy in cancer cells

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1. scibot 28 Jan 2023
  
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sciencedirect.com/science/article/pii/S2451945623000235
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BPS Publications

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1. scibot 14 Jan 2023
  
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  DOI: 10.1111/bph.15997
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15997
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SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111984
  
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sciencedirect.com/science/article/pii/S2211124722018885
Jul 2022
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Rapid macropinocytic transfer of α-synuclein to lysosomes

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111102
  
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sciencedirect.com/science/article/pii/S2211124722009044
Feb 2022
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Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration

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  DOI: 10.1016/j.isci.2022.103842
  
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sciencedirect.com/science/article/pii/S2589004222001122
Nov 2021
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PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

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1. scibot 24 Nov 2021
  
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  DOI: 10.1038/s41419-021-04372-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8599682/
Oct 2021
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Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

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1. scibot 23 Oct 2021
  
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  DOI: 10.7554/eLife.72328
  
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elifesciences.org/articles/72328
Jul 2021
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Regulation of the endosomal SNX27-retromer by OTULIN

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1. scibot 30 Jul 2021
  
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  DOI: 10.1038/s41467-019-12309-z
  
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nature.com/articles/s41467-019-12309-z
May 2021
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NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.devcel.2020.11.016
  
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sciencedirect.com/science/article/pii/S1534580720309254
Apr 2021
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Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

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1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.devcel.2021.03.032
  
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sciencedirect.com/science/article/pii/S1534580721003075
Nov 2020
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Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

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1. scibot 26 Nov 2020
  
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  DOI: 10.7554/eLife.55547
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7673780/
Jan 2020
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Regulation of Autophagic Flux by the 20S Proteasome

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  DOI: 10.1016/j.chembiol.2019.07.002
  
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Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen

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  DOI: 10.1016/j.chom.2019.08.017
  
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sciencedirect.com/science/article/pii/S1931312819304263
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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

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  DOI: 10.1016/j.cell.2019.07.002
  
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CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation

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  DOI: 10.1016/j.celrep.2019.06.079
  
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sciencedirect.com/science/article/pii/S2211124719308599
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Untitled document

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  DOI: 10.1016/j.celrep.2019.04.070
  
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sciencedirect.com/science/article/pii/S2211124719305431