Hypothesis

20 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

Human GBP4 promotes TRIM21-BIP-dependent autophagy to restrict M. tuberculosis infection by preventing SORT1-mediated progranulin degradation

1
1. scibot 27 Jul 2026
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.celrep.2026.117739
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472600817X
Jun 2026
www.sciencedirect.com www.sciencedirect.com

Characterization of a transmembrane-activating STING agonist using genetically humanized mice

1
1. scibot 03 Jun 2026
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.celrep.2026.117475
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472600553X
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Graded activation of the CLEAR network through mTORC1 suppression on cargo-harboring lysosomes

1
1. scibot 11 Apr 2026
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.celrep.2026.117228
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726003062
Jan 2026
www.sciencedirect.com www.sciencedirect.com

Lysosome-localized IRTKS condensates promote mTORC1 activity leading to MASLD and HCC

1
1. scibot 23 Jan 2026
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.celrep.2025.116893
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725016651
Dec 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 06 Dec 2025
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1111/bph.70261
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70261
May 2025
www.sciencedirect.com www.sciencedirect.com

YTHDF1 differentiates the contributing roles of mTORC1 in aging

1
1. scibot 29 May 2025
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.molcel.2025.05.003
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525004083
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1

1
1. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.cmet.2024.11.012
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413124004807
Dec 2024
www.cell.com www.cell.com

TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression

1
1. scibot 29 Dec 2024
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.devcel.2024.12.005
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

cell.com/developmental-cell/fulltext/S1534-5807(24)00727-5
www.sciencedirect.com www.sciencedirect.com

The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

1
1. scibot 17 Dec 2024
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.immuni.2024.11.017
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761324005326
Sep 2024
www.sciencedirect.com www.sciencedirect.com

A TBK1-independent primordial function of STING in lysosomal biogenesis

1
1. scibot 25 Sep 2024
  
  in Public
  
  AB_2799117
  
  DOI: 10.1016/j.molcel.2024.08.026
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524007032
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Sestrin2 drives ER-phagy in response to protein misfolding

1
1. scibot 18 Aug 2024
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.devcel.2024.07.004
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580724004416
Feb 2024
www.sciencedirect.com www.sciencedirect.com

The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

1
1. scibot 08 Feb 2024
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.molcel.2024.01.012
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524000480
Dec 2023
www.sciencedirect.com www.sciencedirect.com

MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

1
1. scibot 16 Dec 2023
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.molcel.2023.11.023
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276523009681
www.sciencedirect.com www.sciencedirect.com

Nutrient-regulated control of lysosome function by signaling lipid conversion

1
1. scibot 02 Dec 2023
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.cell.2023.09.027
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867423010814
Nov 2023
www.sciencedirect.com www.sciencedirect.com

An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.celrep.2023.113484
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014961
Sep 2023
www.embopress.org www.embopress.org

CCDC50 promotes tumor growth through regulation of lysosome homeostasis

1
1. scibot 12 Sep 2023
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.15252/embr.202356948
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

embopress.org/doi/full/10.15252/embr.202356948
May 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1002/cac2.12332
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/cac2.12332
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity

1
1. scibot 23 Feb 2023
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.isci.2023.106169
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223002468
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Ring domains are essential for GATOR2-dependent mTORC1 activation

1
1. scibot 18 Dec 2022
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.molcel.2022.11.021
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522011340
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Itaconate is a lysosomal inducer that promotes antibacterial innate immunity

1
1. scibot 08 Jun 2022
  
  in Public
  
  RRID:AB_2799117
  
  DOI: 10.1016/j.molcel.2022.05.009
  
  Resource: (Cell Signaling Technology Cat# 37681, RRID:AB_2799117)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2799117
  
  What is this?
  
  RRID:AB_2799117
Visit annotations in context

Tags

RRID:AB_2799117

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522004439