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Aug 2025
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Structural insights into the activation of TMEM175 by small molecule

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1. scibot 27 Aug 2025
  
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  DOI: 10.1016/j.neuron.2025.07.029
  
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sciencedirect.com/science/article/pii/S0896627325005562
Jul 2025
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NEDD4 Promotes Sertoli Cell Proliferation and Adult Leydig Cell Differentiation in the Murine Testis

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1. scibot 25 Jul 2025
  
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  DOI: 10.1210/endocr/bqaf115
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12280327/
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Phenotypic screening in influenza-infected zebrafish identifies Nrf2-mediated compound protective against ischemia-reperfusion injury

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sciencedirect.com/science/article/pii/S2589004225013264
Jun 2025
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PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer

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1. scibot 24 Jun 2025
  
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PRPS activity tunes redox homeostasis in Myc-driven lymphoma

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1. scibot 18 Jun 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
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ATG9A and ARFIP2 cooperate to control PI4P levels for lysosomal repair

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.devcel.2025.05.007
  
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May 2025
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Dysregulation of Labile Iron Predisposes Chemotherapy Resistant Cancer Cells to Ferroptosis

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1. scibot 21 May 2025
  
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  DOI: 10.3390/ijms26094193
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12072162/
Mar 2025
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1. scibot 25 Mar 2025
  
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52.53.155.43/f807b69f98daf6a4cef5a05f921f601dbf8242ee/PDF-html.html
Dec 2024
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MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115104
  
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sciencedirect.com/science/article/pii/S2211124724014554
Oct 2024
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Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux

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1. scibot 05 Oct 2024
  
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  DOI: 10.1016/j.chembiol.2023.06.016
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
Sep 2024
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ZIKV Induces P62-Mediated Autophagic Degradation of TRAF6 through TRAF6-NS1 Interaction

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1. scibot 25 Sep 2024
  
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Jul 2024
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Inhibition of SIRT1 relieves hepatocarcinogenesis via alleviating autophagy and inflammation

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.ijbiomac.2024.134120
  
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Apr 2024
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Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis

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1. scibot 30 Apr 2024
  
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  DOI: 10.1186/s13578-024-01230-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
Mar 2024
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Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability

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sciencedirect.com/science/article/pii/S1550413124000500
Feb 2024
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BPS Publications

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1. scibot 16 Feb 2024
  
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  DOI: 10.1111/bph.16283
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.012
  
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  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480
Jan 2024
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Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.molcel.2023.12.010
  
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sciencedirect.com/science/article/pii/S1097276523010298
Oct 2023
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TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2

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  DOI: 10.1016/j.celrep.2023.113231
  
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sciencedirect.com/science/article/pii/S2211124723012433
Sep 2023
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CCDC50 promotes tumor growth through regulation of lysosome homeostasis

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1. scibot 12 Sep 2023
  
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  DOI: 10.15252/embr.202356948
  
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embopress.org/doi/full/10.15252/embr.202356948
Aug 2023
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Boosting NAD preferentially blunts Th17 inflammation via arginine biosynthesis and redox control in healthy and psoriasis subjects

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  DOI: 10.1016/j.xcrm.2023.101157
  
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sciencedirect.com/science/article/pii/S2666379123003105
Jun 2023
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Restored autophagy is protective against PAK3-induced cardiac dysfunction

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  DOI: 10.1016/j.isci.2023.106970
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
Dec 2022
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Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways

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1. scibot 14 Dec 2022
  
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  DOI: 10.3390/ijms231911445
  
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52.53.155.43/eb3e7bd6fec17f8c00ac186e434aef30e82c163b/ijms-23-11445-html.html
Oct 2022
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SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis

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1. scibot 12 Oct 2022
  
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  DOI: 10.1016/j.ebiom.2022.104278
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9535427/
Jan 2022
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Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation

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sciencedirect.com/science/article/pii/S0753332222000038
Nov 2021
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PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

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1. scibot 24 Nov 2021
  
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  DOI: 10.1038/s41419-021-04372-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8599682/
Aug 2021
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Apocynin prevents cigarette smoking‐induced loss of skeletal muscle mass and function in mice by preserving proteostatic signalling

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1. scibot 19 Aug 2021
  
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  DOI: 10.1111/bph.15482
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8362135/
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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

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  DOI: 10.1016/j.cell.2021.07.020
  
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sciencedirect.com/science/article/pii/S0092867421008795
May 2021
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NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

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sciencedirect.com/science/article/pii/S1534580720309254
Feb 2021
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Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

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  DOI: 10.1016/j.cmet.2020.12.011
  
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