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Feb 2026
www.biorxiv.org www.biorxiv.org

Mechanistic Language Modeling and Oxygenated 3D Screening Reveal Berberine and Enzalutamide Synergy in Resistant Prostate Cancer

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  DOI: 10.64898/2026.01.24.701539
  
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biorxiv.org/content/10.64898/2026.01.24.701539v1
Dec 2025
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Macrophage PD-1 regulates energy expenditure and metabolic dysfunction under immune checkpoint blockade

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1. scibot 11 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.009
  
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sciencedirect.com:5037/science/article/pii/S1550413125004930
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan

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  DOI: 10.1016/j.celrep.2025.116422
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12626231/
Sep 2025
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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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1. scibot 24 Sep 2025
  
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  DOI: 10.1016/j.molcel.2025.08.035
  
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sciencedirect.com/science/article/pii/S1097276525007415
Jul 2025
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Cinnabarinic acid protects against metabolic dysfunction-associated steatohepatitis by activating Aryl hydrocarbon Receptor-dependent AMPK signaling

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1. scibot 16 Jul 2025
  
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  DOI: 10.1152/ajpgi.00337.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12258133/
May 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Tomatidine Ameliorates Diabetes-Induced Cognitive Impairment and Tau Hyperphosphorylation Through the AMPK-TFEB Pathway

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1. scibot 29 May 2025
  
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  DOI: 10.1111/jnc.70087
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70087
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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1. scibot 23 Mar 2025
  
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  DOI: 10.1101/2025.02.17.638704
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11870510/
Feb 2025
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Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115246
  
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sciencedirect.com/science/article/pii/S2211124725000178
Dec 2024
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Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer

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1. scibot 03 Dec 2024
  
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  DOI: 10.1126/scisignal.adp1375
  
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science.org/doi/10.1126/scisignal.adp1375
Sep 2024
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Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114652
  
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sciencedirect.com/science/article/pii/S2211124724010039
Jul 2024
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Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114445
  
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sciencedirect.com/science/article/pii/S2211124724007745
Apr 2024
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Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation

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1. scibot 25 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.04.009
  
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sciencedirect.com/science/article/pii/S153458072400234X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle

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1. scibot 10 Apr 2024
  
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  DOI: 10.1038/s41598-024-58716-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10998866/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin alleviates hepatic iron overload and ferroptosis through AMPK-ferroportin pathway in HFD-induced NAFLD

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1. scibot 13 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108560
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10711470/
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Alternating current electromagnetic field exposure lessens intramyocellular lipid accumulation due to high-fat feeding via enhanced lipid metabolism in mice

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1. scibot 30 Nov 2023
  
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  DOI: 10.1371/journal.pone.0289086
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10681264/
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CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions

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1. scibot 02 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113306
  
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sciencedirect.com/science/article/pii/S2211124723013189
Jun 2023
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Resolvin D1 reprograms energy metabolism to promote microglia to phagocytize neutrophils after ischemic stroke

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1. scibot 07 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112617
  
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sciencedirect.com/science/article/pii/S2211124723006289
May 2023
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ATROPHIC REMODELING OF THE HEART DURING VITAMIN D DEFICIENCY AND INSUFFICIENCY IN A RAT MODEL

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1. scibot 20 May 2023
  
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  DOI: 10.1016/j.jnutbio.2023.109382
  
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sciencedirect.com/science/article/pii/S0955286323001158
Jan 2023
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Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

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1. scibot 11 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111941
  
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sciencedirect.com/science/article/pii/S2211124722018423
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke

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1. scibot 02 Dec 2022
  
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  DOI: 10.1016/j.isci.2022.105527
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9708789/
Nov 2022
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AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity

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1. scibot 17 Nov 2022
  
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  DOI: 10.1016/j.molcel.2022.10.026
  
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sciencedirect.com/science/article/pii/S1097276522010541
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation

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1. scibot 30 Sep 2022
  
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  DOI: 10.3389/fimmu.2022.931087
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
Jun 2022
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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

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1. scibot 01 Jun 2022
  
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  DOI: 10.3389/fphar.2022.848957
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
Mar 2022
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Crry silencing alleviates Alzheimer’s disease injury by regulating neuroinflammatory cytokines and the complement system

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1. scibot 04 Mar 2022
  
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  DOI: 10.4103/1673-5374.332160
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8820699/
Dec 2021
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CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110060
  
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sciencedirect.com/science/article/pii/S2211124721015461
Sep 2021
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Rosiglitazone requires hepatocyte PPARγ expression to promote steatosis in male mice with diet-induced obesity

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1. scibot 30 Sep 2021
  
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  DOI: 10.1210/endocr/bqab175
  
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academic.oup.com/endo/article/162/11/bqab175/6356057
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Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK

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1. scibot 23 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.08.025
  
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sciencedirect.com/science/article/pii/S1097276521006924
Sep 2020
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Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.chom.2020.01.028
  
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sciencedirect.com/science/article/pii/S1931312820300718
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Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism

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  DOI: 10.1016/j.cmet.2020.02.015
  
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cell.com/cell-metabolism/fulltext/S1550-4131(20)30074-7
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Intermittent fasting promotes adult hippocampal neuronal differentiation by activating GSK‐3β in 3xTg‐AD mice

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1. scibot 09 Sep 2020
  
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  DOI: 10.1111/jnc.15105
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15105
journals.physiology.org journals.physiology.org

A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics | American Journal of Physiology-Cell Physiology

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1. scibot 01 Sep 2020
  
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  DOI: 10.1152/ajpcell.00383.2019
  
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  Curator comments: Phospho-AMPKα (Thr172) (D4D6D) Rabbit mAb antibody Cell Signaling Technology Cat# 50081
  
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journals.physiology.org/doi/full/10.1152/ajpcell.00383.2019
Jan 2020
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PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.09.018
  
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sciencedirect.com/science/article/pii/S1097276519307233
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BPS Publications

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1. scibot 13 Jan 2020
  
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  RRID:AB_2799368
  
  DOI: 10.1111/bph.14694
  
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bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14694