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Circulating FABP5 released by dying macrophages function as a DAMP to exacerbate septic inflammation

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Sep 2025
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Pathogenic phosphorylation of linear ubiquitin machinery causes inflammasome sensor degradation

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Dehydrocostus Lactone Effectively Alleviates Inflammatory Diseases by Covalently and Irreversibly Targeting NLRP3

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Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease

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TREM2‐Mediated Myeloid Cells Protect Against Pathological Choroidal Neovascularization

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Colchicine inhibits vascular calcification by suppressing inflammasome activation through the enhancement of the Sirt2-PP2Ac signaling pathway

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Piezo1 senses hyphae and initiates host defense against pathogenic fungi

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May 2025
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Inhibition of histone deacetylase 6 activity mitigates neurological impairment and post-hemorrhagic hydrocephalus after intraventricular hemorrhage by modulating pyroptosis and autophagy pathways

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Apr 2025
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Lysosome positioning affects NLRP3 inflammasome activation

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Pyroptosis of pulmonary fibroblasts and macrophages through NLRC4 inflammasome leads to acute respiratory failure

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Dec 2024
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation

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Jul 2024
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Inhibition of SIRT1 relieves hepatocarcinogenesis via alleviating autophagy and inflammation

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NLRP3 promotes allergic responses to birch pollen extract in a model of intranasal sensitization

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Jun 2024
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Inhibition of NLRP3 inflammasome alleviates cognitive deficits in a mouse model of anti-NMDAR encephalitis induced by active immunization

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May 2024
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Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists

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Apr 2024
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NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation

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1. scibot 09 Apr 2024
  
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Mar 2024
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A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages

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Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome

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Feb 2024
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BPS Publications

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  DOI: 10.1111/bph.16283
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
Jan 2024
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Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7

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ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis

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Dec 2023
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ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation

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Nov 2023
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Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization

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Oct 2023
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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

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Jul 2023
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Bexarotene improves motor function after spinal cord injury in mice

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Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

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Jun 2023
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Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice

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  DOI: 10.3390/antiox12061303
  
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mdpi.com/2076-3921/12/6/1303
May 2023
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Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome

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Apr 2023
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The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome

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Mar 2023
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TUG-891 inhibits neuronal endoplasmic reticulum stress and... : Neural Regeneration Research

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journals.lww.com/nrronline/Fulltext/2023/10000/TUG_891_inhibits_neuronal_endoplasmic_reticulum.34.aspx
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Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity

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Feb 2023
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Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation

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  DOI: 10.1016/j.immuni.2023.01.015
  
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Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6

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  DOI: 10.1007/s12035-023-03232-y
  
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Nov 2022
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Commensal cow Roseburia reduces gut-dysbiosis-induced mastitis through inhibiting bacterial translocation by producing butyrate in mice

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Kynurenic acid ameliorates NLRP3 inflammasome activation by blocking calcium mobilization via GPR35

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  DOI: 10.3389/fimmu.2022.1019365
  
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Jun 2022
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Investigating the NLRP3 Inflammasome and its Regulator miR-223-3p in Multiple Sclerosis and Experimental Demyelination

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  DOI: 10.1111/jnc.15650
  
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Apr 2022
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Obstructive sleep apnea aggravates neuroinflammation and... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.339000
  
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Mar 2022
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Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury

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  DOI: 10.1186/s12974-022-02427-9
  
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miR-155 activates the NLRP3 inflammasome by regulating the MEK/ERK/NF-κB pathway in carotid atherosclerotic plaques in ApoE−/− mice

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  DOI: 10.1007/s13105-022-00871-y
  
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Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis

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  DOI: 10.1111/bph.15702
  
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NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation

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  DOI: 10.1016/j.cell.2021.11.011
  
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Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome

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Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

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May 2021
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A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade

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Nov 2020
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LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

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  DOI: 10.7554/eLife.59704
  
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Sep 2020
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  DOI: 10.1111/bph.14806
  
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β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

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  DOI: 10.1111/bph.15182
  
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