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    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
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  3. Sep 2024
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    SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation
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  5. Aug 2024
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    FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia
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  7. Jul 2024
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    ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells
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    Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
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  10. Jun 2024
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    Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia
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    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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  13. May 2024
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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    linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
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    Monocyte bioenergetics: An immunometabolic perspective in metabolic dysfunction-associated steatohepatitis
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    ATGL mediated adipocyte lipolysis exacerbates acute pancreatitis severity in mouse models and patients
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  20. Apr 2024
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    Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis
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    Cancer immunotherapy via synergistic co-activation of myeloid receptors CD40 and Dectin-1
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    Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation
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    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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    Intratumor microbiome-derived butyrate promotes lung cancer metastasis
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  26. Mar 2024
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    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
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  28. Feb 2024
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    Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
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    Loss of TIM4-Dependent Efferocytosis in Kupffer Cells Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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  32. Jan 2024
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    Dietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis
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    PPARγ Deacetylation Suppresses Aging-Associated Atherosclerosis and Hypercholesterolemia
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    AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
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  36. Dec 2023
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    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas
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    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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    Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1
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  43. Nov 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    Host-microbiome interactions in distinct subsets of preterm labor and birth
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    Fibroblast Growth Factor 23 Neutralizing Antibody Ameliorates Abnormal Renal Phosphate Handling in Sickle Cell Disease Mice
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      DOI: 10.1210/endocr/bqad173

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  48. www.nature.com www.nature.com
    Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
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    CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions
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  51. Oct 2023
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    HDL inhibits pancreatic acinar cell NLRP3 inflammasome activation and protect against acinar cell pyroptosis in acute pancreatitis
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    Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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  55. Sep 2023
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    Effects of butyl benzyl phthalate exposure during pregnancy and lactation on the post-involution mammary gland
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    Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
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  58. Aug 2023
  59. 52.53.155.43 52.53.155.43
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    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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  63. Jun 2023
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    Sublethal necroptosis signaling promotes inflammation and liver cancer
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    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
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  68. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors
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  71. Apr 2023
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    Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells
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    Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers
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    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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  76. Feb 2023
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    Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma
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  78. Jan 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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    A single-cell atlas of murine reproductive tissues during preterm labor
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  82. Dec 2022
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    GABA regulates IL-1β production in macrophages
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    Mouse placenta fetal macrophages arise from endothelial cells outside the placenta
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  85. Nov 2022
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice
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  90. Aug 2022
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    Human colon cancer-derived Clostridioides difficile strains drive colonic tumorigenesis in mice
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  92. Jun 2022
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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  95. May 2022
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    Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer
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  97. Apr 2022
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    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  100. Mar 2022
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    A murine model of cerebral cavernous malformations with acute hemorrhage
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    Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
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  104. Feb 2022
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    A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis
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    sciencedirect.com/science/article/pii/S1550413122000043
  106. Nov 2021
  107. www.sciencedirect.com www.sciencedirect.com
    ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
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    1. scibot 17 Nov 2021
      RRID:AB_2799771

      DOI: 10.1016/j.celrep.2021.110003

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    sciencedirect.com/science/article/pii/S2211124721014819
  108. www.sciencedirect.com www.sciencedirect.com
    TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
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    1. scibot 17 Nov 2021
      RRID:AB_2799771

      DOI: 10.1016/j.celrep.2021.110018

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    sciencedirect.com/science/article/pii/S221112472101500X
  109. Aug 2021
  110. www.sciencedirect.com www.sciencedirect.com
    Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice
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    1. scibot 18 Aug 2021
      RRID:AB_2799771

      DOI: 10.1016/j.celrep.2021.109543

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    sciencedirect.com/science/article/pii/S2211124721009773
  111. May 2021
  112. www.nature.com www.nature.com
    Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
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    1. scibot 12 May 2021
      RRID:AB_2799771

      DOI: 10.1038/s41586-021-03461-y

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    nature.com/articles/s41586-021-03461-y
  113. Apr 2021
  114. www.sciencedirect.com www.sciencedirect.com
    Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo
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      RRID:AB_2799771

      DOI: 10.1016/j.cmet.2020.09.006

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    sciencedirect.com/science/article/pii/S1550413120304848
  115. www.sciencedirect.com www.sciencedirect.com
    The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis
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      anti-mouse-F4/80

      DOI: 10.1016/j.bcp.2021.114542

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    sciencedirect.com/science/article/pii/S0006295221001386
  116. Mar 2021
  117. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID: AB_2799771

      DOI: 10.1111/bph.15277

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15277
  118. Jan 2021
  119. www.sciencedirect.com www.sciencedirect.com
    Interleukin-24 protects against liver injury in mouse models
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    1. scibot 28 Jan 2021
      RRID:AB_2799771

      DOI: 10.1016/j.ebiom.2021.103213

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    sciencedirect.com/science/article/pii/S2352396421000062
  120. Dec 2020
  121. www.sciencedirect.com www.sciencedirect.com
    Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution
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    1. scibot 13 Dec 2020
      RRID:AB_2799771

      DOI: 10.1016/j.celrep.2020.108472

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    sciencedirect.com/science/article/pii/S2211124720314613
  122. Sep 2020
  123. www.sciencedirect.com www.sciencedirect.com
    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    1. scibot 14 Sep 2020
      RRID:AB_2799771

      DOI: 10.1016/j.ccell.2020.01.011

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    sciencedirect.com/science/article/pii/S1535610820300507