43 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
    1
    1. scibot 07 Nov 2024
      RRID:AB_2799831

      DOI: 10.3389/fonc.2024.1441935

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
    1
    1. scibot 26 Sep 2024
      RRID:AB_2799831

      DOI: 10.1016/j.isci.2024.110693

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
  5. Jul 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
    1
    1. scibot 27 Jul 2024
      RRID:AB_2799831

      DOI: 10.1016/j.isci.2024.110285

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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesoporous manganese nanocarrier target delivery metformin for the co-activation STING pathway to overcome immunotherapy resistance
    1
    1. scibot 26 Jul 2024
      RRID:AB_2799831

      DOI: 10.1016/j.isci.2024.110150

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    ncbi.nlm.nih.gov/pmc/articles/PMC11261061/
  8. www.sciencedirect.com www.sciencedirect.com
    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
  9. www.cell.com www.cell.com
    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
    1
    1. scibot 12 Jul 2024
      RRID:AB_2799831

      DOI: 10.1016/j.xcrm.2024.101648

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
  10. Jun 2024
  11. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.031

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    sciencedirect.com/science/article/pii/S0092867424005762
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity
    1
    1. scibot 08 Jun 2024
      RRID:AB_2799831

      DOI: 10.1158/2326-6066.CIR-23-1078

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148535/
  13. May 2024
  14. 52.53.155.43 52.53.155.43
    cir-23-1078-html.html
    1
    1. scibot 23 May 2024
      AB_2799831

      DOI: 10.1158/2326-6066.cir-23-1078

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    52.53.155.43/ee0bd7762d373e957152429ed1d9032329c895e5/cir-23-1078-html.html
  15. www.sciencedirect.com www.sciencedirect.com
    Development of nitroalkene-based inhibitors to target STING-dependent inflammation
    1
    1. scibot 23 May 2024
      RRID:AB_2799831

      DOI: 10.1016/j.redox.2024.103202

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    sciencedirect.com/science/article/pii/S2213231724001800
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
    1
    1. scibot 30 Apr 2024
      RRID:AB_2799831

      DOI: 10.1016/j.xcrm.2024.101528

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    sciencedirect.com/science/article/pii/S2666379124001976
  18. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
    1
    1. scibot 26 Apr 2024
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2024.04.004

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    sciencedirect.com/science/article/pii/S1535610824001284
  19. www.sciencedirect.com www.sciencedirect.com
    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
    1. scibot 11 Apr 2024
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2024.114088

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    sciencedirect.com/science/article/pii/S2211124724004169
  20. Mar 2024
  21. www.sciencedirect.com www.sciencedirect.com
    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
    2
    1. scibot 01 Mar 2024
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2024.113870

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    2. scibot 01 Mar 2024
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2024.113870

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    sciencedirect.com/science/article/pii/S2211124724001980
  22. Jan 2024
  23. www.sciencedirect.com www.sciencedirect.com
    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
    1
    1. scibot 07 Jan 2024
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.113626

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    sciencedirect.com/science/article/pii/S2211124723016376
  24. Nov 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
    1
    1. scibot 30 Nov 2023
      RRID:AB_2799831

      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  26. Aug 2023
  27. www.sciencedirect.com www.sciencedirect.com
    4-Octyl itaconate restricts STING activation by blocking its palmitoylation
    1
    1. scibot 25 Aug 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.113040

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    sciencedirect.com/science/article/pii/S2211124723010513
  28. Jul 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy
    1
    1. scibot 27 Jul 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.112852

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    sciencedirect.com/science/article/pii/S221112472300863X
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
    1
    1. scibot 02 Jun 2023
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2023.05.005

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    sciencedirect.com/science/article/pii/S1535610823001733
  32. Apr 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING
    1
    1. scibot 26 Apr 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.112442

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    sciencedirect.com/science/article/pii/S2211124723004539
  34. www.sciencedirect.com www.sciencedirect.com
    Lithium ameliorates Niemann-Pick C1 disease phenotypes by impeding STING/SREBP2 activation
    1
    1. scibot 22 Apr 2023
      RRID:AB_2799831

      DOI: 10.1016/j.isci.2023.106613

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    sciencedirect.com/science/article/pii/S2589004223006909
  35. Mar 2023
  36. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
    1
    1. scibot 28 Mar 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.112303

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    europepmc.org/article/med/36952341
  37. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
    1
    1. scibot 28 Mar 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.112306

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    sciencedirect.com/science/article/pii/S2211124723003170
  38. www.sciencedirect.com www.sciencedirect.com
    NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking
    1
    1. scibot 02 Mar 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.112185

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    sciencedirect.com/science/article/pii/S2211124723001961
  39. www.sciencedirect.com www.sciencedirect.com
    4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING
    1
    1. scibot 02 Mar 2023
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2023.112145

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    sciencedirect.com/science/article/pii/S2211124723001560
  40. Dec 2022
  41. www.sciencedirect.com www.sciencedirect.com
    The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER
    1
    1. scibot 24 Dec 2022
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2022.111868

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    sciencedirect.com/science/article/pii/S2211124722017648
  42. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived type I interferons instruct tumor monocyte polarization
    1
    1. scibot 08 Dec 2022
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2022.111769

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    sciencedirect.com/science/article/pii/S2211124722016527
  43. Sep 2022
  44. www.sciencedirect.com www.sciencedirect.com
    ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
    1
    1. scibot 07 Sep 2022
      RRID:AB_2799831

      DOI: 10.1016/j.immuni.2022.08.006

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    sciencedirect.com/science/article/pii/S1074761322003995
  45. Jun 2022
  46. rupress.org rupress.org
    ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
    1
    1. scibot 09 Jun 2022
      RRID:AB_2799831

      DOI: 10.1083/jcb.202106046

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    rupress.org/jcb/article/221/7/e202106046/213259/ER-lysosome-lipid-transfer-protein-VPS13C-PARK23
  47. May 2022
  48. www.sciencedirect.com www.sciencedirect.com
    STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
    1
    1. scibot 26 May 2022
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2022.110838

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    sciencedirect.com/science/article/pii/S2211124722006118
  49. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
    1
    1. scibot 11 May 2022
      RRID:AB_279983

      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  50. Jan 2022
  51. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
    1
    1. scibot 05 Jan 2022
      RRID:AB_2799831

      DOI: 10.1016/j.cmet.2021.12.007

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    sciencedirect.com/science/article/pii/S1550413121006264
  52. Jul 2021
  53. www.nature.com www.nature.com
    Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
    1
    1. scibot 31 Jul 2021
      72971

      DOI: 10.1038/s41586-021-03762-2

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    nature.com/articles/s41586-021-03762-2
  54. May 2021
  55. www.sciencedirect.com www.sciencedirect.com
    SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function
    1
    1. scibot 08 May 2021
      RRID:AB_2799831

      DOI: 10.1016/j.molcel.2020.12.024

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    sciencedirect.com/science/article/pii/S109727652030945X
  56. www.sciencedirect.com www.sciencedirect.com
    LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
    1
    1. scibot 08 May 2021
      RRID:AB_2799831

      DOI: 10.1016/j.molcel.2020.10.021

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    sciencedirect.com/science/article/pii/S1097276520307280
  57. Apr 2021
  58. www.sciencedirect.com www.sciencedirect.com
    MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
    1
    1. scibot 22 Apr 2021
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2020.11.004

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    sciencedirect.com/science/article/pii/S1535610820305961
  59. www.sciencedirect.com www.sciencedirect.com
    Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
    1
    1. scibot 17 Apr 2021
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2020.05.020

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    sciencedirect.com/science/article/pii/S1535610820302701
  60. Sep 2020
  61. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
    1
    1. scibot 23 Sep 2020
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2020.03.056

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    sciencedirect.com/science/article/pii/S2211124720303703
  62. www.sciencedirect.com www.sciencedirect.com
    Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
    1
    1. scibot 16 Sep 2020
      RRID:AB_2799831

      DOI: 10.1016/j.immuni.2020.03.016

      Resource: (Cell Signaling Technology Cat# 72971, RRID:AB_2799831)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2799831

      What is this?
      RRIDCUR:Validated RRID:AB_2799831
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    sciencedirect.com/science/article/pii/S1074761320301291
  63. www.sciencedirect.com www.sciencedirect.com
    mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury
    1
    1. scibot 06 Sep 2020
      RRID:AB_2799831

      DOI: 10.1016/j.immuni.2020.02.002

      Resource: (Cell Signaling Technology Cat# 72971, RRID:AB_2799831)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2799831

      What is this?
      RRIDCUR:Validated RRID:AB_2799831
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    sciencedirect.com/science/article/pii/S107476132030073X
  64. www.nature.com www.nature.com
    C9orf72 in myeloid cells suppresses STING-induced inflammation
    1
    1. scibot 03 Sep 2020
      phospo-STING Ser 365

      DOI: 10.1038/s41586-020-2625-x

      Resource: (Cell Signaling Technology Cat# 72971, RRID:AB_2799831)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2799831

      Curator comments: Phospho-STING (Ser365) (D8F4W) Rabbit mAb antibody Cell Signaling Technology Cat# 72971

      What is this?
      RRID:AB_2799831 RRIDCUR:Missing
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    nature.com/articles/s41586-020-2625-x
  65. Jan 2020
  66. www.sciencedirect.com www.sciencedirect.com
    CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2019.11.003

      Resource: (Cell Signaling Technology Cat# 72971, RRID:AB_2799831)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2799831

      What is this?

      RRID:AB_2799831 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819305239