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Activation of TREM2 via single-domain antibodies improves synaptic and cognitive function in 5×FAD mice

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1. scibot 01 Oct 2026
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.celrep.2026.118063
  
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sciencedirect.com/science/article/pii/S2211124726011423
Feb 2026
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Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors

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1. scibot 03 Feb 2026
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.immuni.2026.01.014
  
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sciencedirect.com/science/article/pii/S1074761326000361
Oct 2025
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The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function

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1. scibot 18 Oct 2025
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.neuron.2025.09.032
  
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sciencedirect.com/science/article/pii/S0896627325007457
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TREM2 deficiency aggravates neuroinflammatory response and cognitive impairment via disease-associated microglia in Parkinson’s disease models

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1. scibot 08 Oct 2025
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.neuint.2025.106068
  
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sciencedirect.com/science/article/pii/S019701862500141X
Jan 2025
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Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115204
  
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sciencedirect.com/science/article/pii/S2211124724015559
Apr 2024
52.53.155.43 52.53.155.43

JNEUROSCI.1563-23.2024.full (1)-html.html

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1. scibot 26 Apr 2024
  
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  RRID:AB_2799888
  
  DOI: 10.1523/jneurosci.1563-23.2024
  
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52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias

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1. scibot 16 Mar 2024
  
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  DOI: 10.1038/s44319-024-00077-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
Feb 2024
www.embopress.org www.embopress.org

Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias

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1. scibot 15 Feb 2024
  
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  DOI: 10.1038/s44319-024-00077-x
  
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embopress.org/doi/10.1038/s44319-024-00077-x
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Protocol for gene knockdown using siRNA in primary cultured neonatal murine microglia

2
1. scibot 14 Feb 2024
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.xpro.2024.102867
  
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2. scibot 14 Feb 2024
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.xpro.2024.102867
  
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sciencedirect.com/science/article/pii/S2666166724000327
Oct 2023
52.53.155.43 52.53.155.43

BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer’s disease and related dementias

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1. scibot 13 Oct 2023
  
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  RRID:AB_2799888
  
  DOI: 10.1101/2023.06.14.544924
  
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52.53.155.43/5afe577c269e488702b5f7086020251c9f5e047d/2023.06.14.544924v1.full-html.html
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep–wake Disturbances in AD Mice

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1. scibot 06 Sep 2023
  
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  AB_2799888
  
  DOI: 10.1523/JNEUROSCI.2124-22.2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10476643/
Aug 2023
52.53.155.43 52.53.155.43

JNEUROSCI.2124-22.2023.full-html.html

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1. scibot 12 Aug 2023
  
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  AB_2799888
  
  DOI: 10.1523/jneurosci.2124-22.2023
  
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52.53.155.43/4dbd467d14205450fc5e72be56a006e617b94e6d/JNEUROSCI.2124-22.2023.full-html.html
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model

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1. scibot 03 Jun 2023
  
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  RRID:AB_279988
  
  DOI: 10.1016/j.isci.2023.106375
  
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  Curator: @a5munoz
  
  SciCrunch record: RRID:AB_2799888
  
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  RRID:AB_2799888 RRIDCUR:Unresolved
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ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
Jan 2023
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Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

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1. scibot 28 Jan 2023
  
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  RRID:AB_2799888
  
  DOI: 10.1016/j.immuni.2022.11.013
  
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sciencedirect.com/science/article/pii/S1074761322006033