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Nov 2026
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E2 displacement of CIP2A from TOPBP1 activates the DNA damage response during papillomavirus life cycles

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  DOI: 10.1016/j.celrep.2026.118209
  
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sciencedirect.com/science/article/pii/S221112472601288X
Sep 2026
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Zonated cholesterol sensing by SIRT2 drives MASLD-HCC

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  DOI: 10.1016/j.cmet.2026.08.015
  
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Aug 2026
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SADS-CoV nucleocapsid protein antagonizes DAD1-mediated STING activation to prevent cytosolic DNA sensing

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  DOI: 10.1016/j.celrep.2026.117917
  
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Jul 2026
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An antibody-PROTAC conjugate targets BRD4/c-Myc/PD-L1 to enhance immunotherapy efficacy in triple-negative breast cancer

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  DOI: 10.1016/j.xcrm.2026.102948
  
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A Peptide-Based PROTAC Degrader of BRCA2 Sensitizes Metastatic Castration-Resistant Prostate Cancer to PARP Inhibition

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-4096
  
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aacrjournals.org/cancerres/article/85/18/3490/764450/A-Peptide-Based-PROTAC-Degrader-of-BRCA2
Jun 2026
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Early replication fragile sites are associated with cancer-related CNVs and SNVs in human embryonic stem cells

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  DOI: 10.1016/j.stemcr.2026.102968
  
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WEE1 kinase inhibition to overcome acquired resistance to targeted therapies in colorectal cancer

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  DOI: 10.1038/s44321-026-00434-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13269805/
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Deacetylated PCBP1 licenses PARP1 activity for DNA damage repair

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  DOI: 10.1016/j.molcel.2026.05.008
  
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Apr 2026
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MDC1 promotes nuclear localization of Beclin-1 and supports its role in ATM pathway in response to oxidative stress

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1. scibot 21 Apr 2026
  
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  DOI: 10.1016/j.ejcb.2026.151540
  
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CBX2 phase-separation contributes to homologous recombination repair and drug resistance in ovarian cancer

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1. scibot 03 Apr 2026
  
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  DOI: 10.1038/s41419-026-08605-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13039389/
Jan 2026
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Protocol to study adult neurogenesis in fresh-frozen human hippocampal tissue using an immunofluorescence quantitative approach

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.xpro.2025.104344
  
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2026.01.07.697614v1.full-html.html

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1. scibot 13 Jan 2026
  
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  DOI: 10.64898/2026.01.07.697614
  
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54.241.53.176/87184a207210a45262d427988504be7f9d95d17e/2026.01.07.697614v1.full-html.html
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Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.013
  
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sciencedirect.com/science/article/pii/S1535610825005471
Dec 2025
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Serotonin-licensed macrophages potentiate chemoresistance via inositol metabolic crosstalk in ovarian cancer

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1. scibot 18 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.011
  
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sciencedirect.com:5037/science/article/pii/S1550413125004954
Nov 2025
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WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116520
  
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Sep 2025
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Human adult hippocampal neurogenesis is shaped by neuropsychiatric disorders, demographics, and lifestyle-related factors

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.stem.2025.08.010
  
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Jul 2025
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Riluzole Enhancing anti-PD-1 Efficacy by Activating cGAS/STING Signaling in Colorectal Cancer

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0289
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695182/
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Combined Radiation and Endocrine Therapies Elicit Benefit in ER+ Breast Cancer

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1. scibot 02 Jul 2025
  
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  DOI: 10.3390/cancers17121921
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12190792/
May 2025
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Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.012
  
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Jul 2024
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Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

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  DOI: 10.1016/j.isci.2024.110144
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
Apr 2024
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Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

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  DOI: 10.1016/j.devcel.2024.03.020
  
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Mar 2024
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Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance

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  DOI: 10.1016/j.celrep.2024.113897
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11209755/
Jan 2024
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DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.ebiom.2023.104801
  
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Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells

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  DOI: 10.1016/j.xcrm.2023.101376
  
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Nov 2023
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Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors

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  DOI: 10.1016/j.isci.2023.108169
  
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Oct 2023
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Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer

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  DOI: 10.1016/j.cmet.2023.10.002
  
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Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells

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  DOI: 10.1016/j.celrep.2023.113308
  
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Sep 2023
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Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction

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  DOI: 10.1016/j.celrep.2023.113176
  
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Jul 2023
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GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner

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  DOI: 10.15252/embr.202256437
  
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Jun 2023
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Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response

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  DOI: 10.1016/j.isci.2023.107090
  
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Apr 2023
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The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage

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  DOI: 10.1016/j.celrep.2023.112332
  
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Jan 2023
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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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1. scibot 26 Jan 2023
  
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  DOI: 10.1016/j.molcel.2022.12.034
  
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sciencedirect.com/science/article/pii/S1097276522012175
Mar 2022
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Poly (ADP-ribose) polymerase 1-mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model

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1. scibot 26 Mar 2022
  
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  DOI: 10.1111/jnc.15606
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15606
Dec 2021
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Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

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1. scibot 17 Dec 2021
  
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  DOI: 10.7554/eLife.70691
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

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  DOI: 10.1016/j.celrep.2021.110069
  
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sciencedirect.com/science/article/pii/S2211124721015552
Aug 2021
academic.oup.com academic.oup.com

COP9 signalosome subunit 3 is necessary for early embryo survival by way of a stable protein deposit in mouse oocytes

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1. scibot 17 Aug 2021
  
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  80312
  
  DOI: 10.1093/molehr/gaab048
  
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academic.oup.com/molehr/article/27/8/gaab048/6321894
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Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair

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1. scibot 03 Aug 2021
  
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  RRID:AB_2799949
  
  DOI: 10.1016/j.cmet.2021.07.009
  
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sciencedirect.com/science/article/pii/S1550413121003259
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability

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1. scibot 18 Jun 2021
  
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  RRID: AB_2799949
  
  DOI: 10.1016/j.isci.2021.102534
  
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2. scibot 18 Jun 2021
  
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  RRID:AB_2799949
  
  DOI: 10.1016/j.isci.2021.102534
  
  Resource: (Cell Signaling Technology Cat# 80312, RRID:AB_2799949)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8184511/
Jan 2021
elifesciences.org elifesciences.org

Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

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1. scibot 06 Jan 2021
  
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  RRID:AB_2799949
  
  DOI: 10.7554/eLife.58037
  
  Resource: (Cell Signaling Technology Cat# 80312, RRID:AB_2799949)
  
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  RRID:AB_2799949 RRIDCUR:Validated
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elifesciences.org/articles/58037
Jan 2020
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RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

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1. scibot 13 Jan 2020
  
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  RRID:AB_2799949
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2451945619304015