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Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation

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1. scibot 20 May 2026
  
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  AB_2799960
  
  DOI: 10.1016/j.devcel.2026.04.012
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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sciencedirect.com/science/article/pii/S1534580726001590
Dec 2025
www.nature.com www.nature.com

CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

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1. scibot 06 Dec 2025
  
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  RRID:AB_2799960
  
  DOI: 10.1038/s41523-025-00851-7
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
  Curator: @evieth
  
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nature.com/articles/s41523-025-00851-7
Jun 2025
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Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells

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1. scibot 04 Jun 2025
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.xcrm.2025.102157
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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sciencedirect.com/science/article/pii/S2666379125002307
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors

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1. scibot 05 Apr 2025
  
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  AB_2799960
  
  DOI: 10.1158/0008-5472.CAN-24-2360
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11967718/
Feb 2025
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Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies

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1. scibot 11 Feb 2025
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.xcrm.2025.101964
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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sciencedirect.com/science/article/pii/S2666379125000370
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

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1. scibot 25 Jan 2025
  
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  RRID:AB_2799960
  
  DOI: 10.1158/1078-0432.CCR-24-0562
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
Dec 2024
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Mapping functional elements of the DNA damage response through base editor screens

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1. scibot 12 Dec 2024
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.celrep.2024.115047
  
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sciencedirect.com/science/article/pii/S2211124724013986
Jul 2024
www.cell.com www.cell.com

Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance

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1. scibot 18 Jul 2024
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.celrep.2024.114409
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00738-1
Oct 2023
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Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development

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1. scibot 27 Oct 2023
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.celrep.2023.113310
  
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sciencedirect.com/science/article/pii/S2211124723013220
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss

1
1. scibot 24 Jun 2023
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.isci.2023.107028
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
Apr 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow

1
1. scibot 06 Apr 2023
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.cmet.2023.03.005
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10127143/
Jul 2022
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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

1
1. scibot 15 Jul 2022
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.cmet.2022.06.010
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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sciencedirect.com/science/article/pii/S1550413122002303
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

1
1. scibot 15 Jan 2022
  
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  RRID:AB_2799960
  
  DOI: 10.1038/s41408-021-00603-3
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
Oct 2021
aacrjournals.org aacrjournals.org

Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling

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1. scibot 01 Oct 2021
  
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  RRID:AB_2799960
  
  DOI: 10.1158/1078-0432.CCR-21-1252
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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aacrjournals.org/clincancerres/article/27/17/4781/671616/Rapid-Serial-Immunoprofiling-of-the-Tumor-Immune
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

1
1. scibot 17 Aug 2021
  
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  RRID:AB_2799960
  
  DOI: 10.1158/1078-0432.CCR-18-3683
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7887036/
Apr 2021
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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

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1. scibot 29 Apr 2021
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.stem.2021.03.005
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
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sciencedirect.com/science/article/pii/S1934590921001119
www.sciencedirect.com www.sciencedirect.com

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

1
1. scibot 14 Apr 2021
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.celrep.2021.108994
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
  Curator: @Naa003
  
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  RRID:AB_2799960 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721003089
Sep 2020
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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

1
1. scibot 11 Sep 2020
  
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  RRID:AB_2799960
  
  DOI: 10.1016/j.ccell.2019.12.006
  
  Resource: (Cell Signaling Technology Cat# 80772, RRID:AB_2799960)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2799960
  
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  RRIDCUR:Validated RRID:AB_2799960
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sciencedirect.com/science/article/pii/S1535610819305768