Hypothesis

33 Matching Annotations

Oct 2026
www.sciencedirect.com www.sciencedirect.com

Macrophage-derived WNT regulates tumor immune microenvironment to reduce colitis-associated colon cancer

1
1. scibot 15 Oct 2026
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.canlet.2026.218879
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0304383526006439
Sep 2026
www.sciencedirect.com www.sciencedirect.com

Neutrophil elastase-mediated myoepithelial loss is a therapeutic vulnerability in ductal carcinoma in situ progression

1
1. scibot 12 Sep 2026
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.xcrm.2026.103050
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379126004672
Jul 2026
54.241.53.176 54.241.53.176

can-25-2892-html.html

1
1. scibot 12 Jul 2026
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1158/0008-5472.CAN-25-2892
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

54.241.53.176/c6898d0bd4c5c229db75f37e33da3318946be280/can-25-2892-html.html
Apr 2026
aacrjournals.org aacrjournals.org

Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy

1
1. scibot 23 Apr 2026
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1158/2159-8290.CD-25-0649
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

aacrjournals.org/cancerdiscovery/article/16/1/155/771238/Activation-of-T-Cell-Intrinsic-p53-by-Acetylation
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Macrophage PD-1 regulates energy expenditure and metabolic dysfunction under immune checkpoint blockade

1
1. scibot 11 Dec 2025
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.cmet.2025.11.009
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S1550413125004930
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression

1
1. scibot 06 Dec 2025
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1158/2767-9764.CRC-25-0267
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12676110/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

1
1. scibot 16 Jul 2025
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.xcrm.2025.102239
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912500312X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combined KRAS inhibition and immune therapy generates durable complete responses in an autochthonous PDAC model

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1158/2159-8290.CD-24-0489
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11858029/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Signatures of H3K4me3 modification predict cancer immunotherapy response and identify a new immune checkpoint-SLAMF9

1
1. scibot 18 Jan 2025
  
  in Public
  
  RRID: AB_2800041
  
  DOI: 10.1186/s12931-024-03093-6
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11734478/
www.sciencedirect.com www.sciencedirect.com

Nanostructured lipid carriers based mRNA vaccine leads to a T cell–inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model

1
1. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.ebiom.2024.105543
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396424005796
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.xcrm.2024.101830
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124006013
Nov 2024
www.sciencedirect.com www.sciencedirect.com

The immune landscape of murine skeletal muscle regeneration and aging

1
1. scibot 20 Nov 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.celrep.2024.114975
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724013263
Sep 2024
www.sciencedirect.com www.sciencedirect.com

CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway

1
1. scibot 26 Sep 2024
  
  in Public
  
  AB_2800041
  
  DOI: 10.1016/j.xgen.2024.100659
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666979X24002702
www.sciencedirect.com www.sciencedirect.com

Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer

1
1. scibot 25 Sep 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.ccell.2024.08.019
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610824003180
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer

1
1. scibot 19 Jul 2024
  
  in Public
  
  AB_2800041
  
  DOI: 10.1016/j.medj.2024.06.002
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666634024002484
www.sciencedirect.com www.sciencedirect.com

Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

1
1. scibot 18 Jul 2024
  
  in Public
  
  AB_2800041
  
  DOI: 10.1016/j.cell.2024.06.013
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424006536
May 2024
www.sciencedirect.com www.sciencedirect.com

Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression

1
1. scibot 30 May 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.immuni.2024.05.004
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761324002553
Apr 2024
www.sciencedirect.com www.sciencedirect.com

IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling

1
1. scibot 11 Apr 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.celrep.2024.114088
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724004169
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma

1
1. scibot 03 Apr 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1158/1078-0432.CCR-23-1003
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

2
1. scibot 28 Feb 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.molcel.2024.01.024
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
2. scibot 21 Feb 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.molcel.2024.01.024
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524000911
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glycolysis Induced by METTL14 Is Essential for Macrophage Phagocytosis and Phenotype in Cervical Cancer

1
1. scibot 02 Feb 2024
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.4049/jimmunol.2300339
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10828180/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

1
1. scibot 02 Dec 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.immuni.2023.11.002
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761323004831
Oct 2023
www.sciencedirect.com www.sciencedirect.com

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

1
1. scibot 13 Oct 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.ccell.2023.09.001
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610823003185
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.celrep.2023.113138
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723011506
Aug 2023
52.53.155.43 52.53.155.43

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

2
1. scibot 17 Aug 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.celrep.2023.112944
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
2. scibot 11 Aug 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.celrep.2023.112944
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
www.sciencedirect.com www.sciencedirect.com

A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

1
1. scibot 16 Aug 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.xcrm.2023.101154
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123003075
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2

1
1. scibot 28 Jun 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.celrep.2023.112693
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723007040
May 2023
www.nature.com www.nature.com

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

1
1. scibot 20 May 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1038/s41467-023-38605-3
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

nature.com/articles/s41467-023-38605-3
www.nature.com www.nature.com

Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells

1
1. scibot 06 May 2023
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1038/s41467-023-38316-9
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

nature.com/articles/s41467-023-38316-9
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis

1
1. scibot 16 Nov 2022
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.xcrm.2022.100821
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379122003809
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection

1
1. scibot 18 Jun 2021
  
  in Public
  
  RRID:AB_2800041
  
  DOI: 10.1016/j.isci.2021.102555
  
  Resource: (Cell Signaling Technology Cat# 84651, RRID:AB_2800041)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800041
  
  What is this?
  
  RRID:AB_2800041
Visit annotations in context

Tags

RRID:AB_2800041

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8188550/