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Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.115698
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12404271/
Jun 2025
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Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets

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1. scibot 24 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.021
  
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sciencedirect.com/science/article/pii/S1074761325002420
May 2025
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Somatic hypermutation unlocks antibody specificities beyond the primary repertoire

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.014
  
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sciencedirect.com/science/article/pii/S1074761325001773
Mar 2025
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Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.03.001
  
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sciencedirect.com/science/article/pii/S1074761325000950
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Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis

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  DOI: 10.1016/j.chom.2025.03.004
  
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sciencedirect.com/science/article/pii/S1931312825000873
Feb 2025
52.53.155.43 52.53.155.43

Mapping intratumoral myeloid-T cell interactomes at single-cell resolution reveals targets for overcoming checkpoint inhibitor resistance

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1. scibot 07 Feb 2025
  
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  DOI: 10.1101/2024.10.28.620093
  
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52.53.155.43/b97c57717b8e9ffd85392521b55861178592850c/2024.10.28.620093.full-html.html
Aug 2024
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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes

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1. scibot 30 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.024
  
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sciencedirect.com/science/article/pii/S107476132400373X
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.016
  
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sciencedirect.com/science/article/pii/S0092867424007761
www.cell.com www.cell.com

The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.006
  
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cell.com/immunity/fulltext/S1074-7613(24)00355-8
Jun 2024
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Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.immuni.2024.05.018
  
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sciencedirect.com/science/article/pii/S1074761324002735
May 2024
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Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers

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1. scibot 09 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.014
  
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sciencedirect.com/science/article/pii/S107476132400219X
Apr 2024
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Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses

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1. scibot 26 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.022
  
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sciencedirect.com/science/article/pii/S1074761324001432
Mar 2024
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NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113898
  
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2. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113898
  
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sciencedirect.com/science/article/pii/S2211124724002262
Feb 2024
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Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis

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1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.009
  
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  DOI: 10.1016/j.immuni.2024.01.009
  
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sciencedirect.com/science/article/pii/S1074761324000347
Jan 2024
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Lack of affinity signature for germinal center cells that have initiated plasma cell differentiation

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1. scibot 20 Jan 2024
  
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  DOI: 10.1016/j.immuni.2023.12.010
  
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sciencedirect.com/science/article/pii/S1074761323005411
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An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains

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  DOI: 10.1016/j.immuni.2023.12.001
  
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sciencedirect.com/science/article/pii/S1074761323005320
Aug 2023
52.53.155.43 52.53.155.43

SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine

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1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112940
  
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2. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112940
  
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52.53.155.43/746dceaaaecd8ad8008d9df523b985f7a77f181a/PIIS2211124723009518-html.html
52.53.155.43 52.53.155.43

Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells

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1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112876
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112876
  
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52.53.155.43/7d9bf3333b9425342ca4204697d643342388db9f/PIIS2211124723008872-html.html
Jun 2023
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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  DOI: 10.1016/j.celrep.2023.112599
  
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sciencedirect.com/science/article/pii/S2211124723006101
May 2023
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Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection

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1. scibot 10 May 2023
  
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  DOI: 10.1016/j.immuni.2023.04.010
  
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sciencedirect.com/science/article/pii/S1074761323001796
Apr 2023
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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.01.033
  
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sciencedirect.com/science/article/pii/S1074761323000456
www.cell.com www.cell.com

Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.03.011
  
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cell.com/cell/fulltext/S0092-8674(23)00271-4
Jan 2023
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Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes

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1. scibot 05 Jan 2023
  
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  DOI: 10.1016/j.chom.2022.12.009
  
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sciencedirect.com/science/article/pii/S1931312822006102
Oct 2022
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Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment

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1. scibot 27 Oct 2022
  
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  DOI: 10.1016/j.cell.2022.10.006
  
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cell.com/cell/fulltext/S0092-8674(22)01321-6
Mar 2022
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Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites

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  DOI: 10.1016/j.immuni.2022.03.003
  
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sciencedirect.com/science/article/pii/S1074761322001261
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Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer

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  DOI: 10.1016/j.celrep.2022.110485
  
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sciencedirect.com/science/article/pii/S2211124722002182
Sep 2021
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Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

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1. scibot 24 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.08.020
  
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sciencedirect.com/science/article/pii/S0092867421009946