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Molecular basis for shifted receptor recognition by an encephalitic arbovirus

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Aug 2025
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The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi

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Jul 2025
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RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

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The planar cell polarity (PCP) protein Fat 1 in Sertoli cell function

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Jun 2025
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The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible

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GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer

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Apr 2025
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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

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Molecular basis for shifted receptor recognition by an encephalitic arbovirus

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PDF-html.html

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Mar 2025
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AGO2 mediates immunotherapy failure via suppressing tumor IFN-gamma response-dependent CD8+ T cell immunity

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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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Feb 2025
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A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation

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Jan 2025
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DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma

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Dec 2024
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Aryl Hydrocarbon Receptor Alleviates Hepatic Fibrosis by Inducing Hepatic Stellate Cell Ferroptosis

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Nov 2024
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can-24-1817-html.html

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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Sep 2024
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ZIKV Induces P62-Mediated Autophagic Degradation of TRAF6 through TRAF6-NS1 Interaction

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CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway

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PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders

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Jul 2024
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Genome-scale exon perturbation screens uncover exons critical for cell fitness

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Jun 2024
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Circ_0007432 promotes non-small cell lung cancer progression and macrophage M2 polarization through SRSF1/KLF12 axis

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May 2024
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Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation

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Apr 2024
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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

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Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects

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Intratumor microbiome-derived butyrate promotes lung cancer metastasis

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Feb 2024
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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

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Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves

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Jan 2024
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Renal macrophages monitor and remove particles from urine to prevent tubule obstruction

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Dec 2023
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Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation

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Oct 2023
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WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation

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May 2023
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Exercise improves homeostasis of the intestinal epithelium by activation of APJ-AMPK signaling

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Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex

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The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html

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52.53.155.43/e6c85c39692a8a492c117b9f4fb49e166812457c/The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html
Apr 2023
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Hepatitis C virus hypervariable region 1 antibodies interrupt E2-SR-B1 interaction to suppress viral infection

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Mar 2023
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Epithelial cells activate fibroblasts to promote esophageal cancer development

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Dec 2022
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TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification

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aacrjournals.org/mcr/article/20/12/1763/711001/TFAP4-Activates-IGF2BP1-and-Promotes-Progression
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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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sciencedirect.com/science/article/pii/S1535610822005529
Dec 2021
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Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

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  DOI: 10.7554/eLife.70691
  
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Oct 2021
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Thy1-positive spermatogonia suppress the proliferation of spermatogonial stem cells by Extracellular vesicles in vitro

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  DOI: 10.1210/endocr/bqab052
  
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academic.oup.com/endo/article/162/7/bqab052/6170580
Aug 2021
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Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

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  DOI: 10.1016/j.isci.2021.102871
  
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FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue

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  DOI: 10.1016/j.celrep.2021.109481
  
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Sep 2020
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SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain

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  DOI: 10.1016/j.cels.2020.03.003
  
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Aug 2020
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YAP regulates cell size and growth dynamics via non-cell autonomous mediators

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  DOI: 10.7554/eLife.53404
  
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