50 Matching Annotations
  1. Mar 2026
  2. www.biorxiv.org www.biorxiv.org
    A Niclosamide Prodrug SSL-0024 with Enhanced Bioavailability Suppresses Hepatocellular Carcinoma via Multi-Pathway Signaling Inhibition
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    biorxiv.org/content/10.64898/2026.03.06.710248v1
  3. Feb 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling
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    sciencedirect.com/science/article/pii/S2589004226001586
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877753/
  6. Dec 2025
  7. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70222
  8. Nov 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hierarchical regulation of cerebellar neurogenesis by Sin3A-mediated gene repression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12632768/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB-Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12625700/
  11. Sep 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined treatment with CDK4/6, CDK2, and CXCR1/2 inhibitors effectively halts the growth of BRAF wild-type melanoma tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402945/
  13. Jun 2025
  14. 52.53.155.43 52.53.155.43
    Overexpression of high affinity Type I adenosine receptors promotes the growth of uterine leiomyomas
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    52.53.155.43/98b549de2dada4d95e18fb3c1cbf3f9e072cd46c/PDF-html.html
  15. May 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11305671/
  17. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
  18. Mar 2025
  19. www.cell.com www.cell.com
    Small-molecule RNA therapeutics to target prostate cancer
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    cell.com/cancer-cell/abstract/S1535-6108(25)00079-0
  20. Feb 2025
  21. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/14aa111ce8a1e5484e892552f2e3d7e5be8c5aa9/PDF-html.html
  22. aacrjournals.org aacrjournals.org
    CCN6 suppresses metaplastic breast carcinoma by antagonizing WNT/β-catenin signaling to inhibit EZH2-driven EMT
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    aacrjournals.org/cancerres/article/84/19/3235/748708/CCN6-Suppresses-Metaplastic-Breast-Carcinoma-by
  23. Jan 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11250573/
  25. Sep 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A benzarone derivative inhibits EYA to suppress tumor growth in SHH medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10948029/
  27. Aug 2024
  28. www.nature.com www.nature.com
    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
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    nature.com/articles/s42255-024-01110-y
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
  30. Jul 2024
  31. www.science.org www.science.org
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    science.org/doi/10.1126/science.adk0775
  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16494
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial transcriptomics analysis identifies a tumor-promoting function of the meningeal stroma in melanoma leptomeningeal disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11228800/
  34. May 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
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    sciencedirect.com/science/article/pii/S2211124724005394
  36. Apr 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022046/
  38. www.sciencedirect.com www.sciencedirect.com
    Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication
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    sciencedirect.com/science/article/pii/S1534580724002004
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148513/
  40. Feb 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Alternative mRNA splicing events and regulators in epidermal differentiation
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    sciencedirect.com/science/article/pii/S2211124724001426
  42. Aug 2023
  43. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Inhibition of CK2α accelerates skin wound healing by promoting endothelial cell proliferation through the Hedgehog signaling pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202300478RR
  44. 52.53.155.43 52.53.155.43
    The FASEB Journal - 2023 - Zhu-html.html
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    52.53.155.43/a41d38676c286895eaed9e9bfff455a4115be563/The FASEB Journal - 2023 - Zhu-html.html
  45. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10403574/
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
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    sciencedirect.com/science/article/pii/S2211124723007155
  49. www.sciencedirect.com www.sciencedirect.com
    Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions
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    sciencedirect.com/science/article/pii/S1534580723002666
  50. May 2023
  51. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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    sciencedirect.com/science/article/pii/S2211124723004904
  52. www.biorxiv.org www.biorxiv.org
    LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration
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    biorxiv.org/content/10.1101/2023.03.18.533289v1
  53. Jan 2023
  54. link.springer.com link.springer.com
    Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia
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    link.springer.com/article/10.1007/s10787-022-01123-7
  55. Dec 2022
  56. www.sciencedirect.com www.sciencedirect.com
    YAP regulates the liver size during the fasting-refeeding transition in mice
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    sciencedirect.com/science/article/pii/S2211383522005196
  57. www.sciencedirect.com www.sciencedirect.com
    Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer
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    sciencedirect.com/science/article/pii/S1535610822005529
  58. Nov 2022
  59. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
  60. Aug 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    sciencedirect.com/science/article/pii/S155041312200345X
  62. Apr 2022
  63. journals.physiology.org journals.physiology.org
    Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway
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    journals.physiology.org/doi/full/10.1152/ajprenal.00023.2022
  64. Oct 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    sciencedirect.com/science/article/pii/S109727652100798X
  66. Sep 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8445623/
  68. Jun 2021
  69. cmbl.biomedcentral.com cmbl.biomedcentral.com
    β-elemene alleviates airway stenosis via the ILK/Akt pathway modulated by MIR143HG sponging miR-1275
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    cmbl.biomedcentral.com/articles/10.1186/s11658-021-00261-0
  70. May 2021
  71. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15435
  72. www.sciencedirect.com www.sciencedirect.com
    LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through MEK/ERK signaling pathway
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    sciencedirect.com/science/article/pii/S2212877821000752
  73. Feb 2021
  74. www.authorea.com www.authorea.com
    Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer
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    authorea.com/users/368637/articles/487712-natural-product-trienomycin-a-is-a-stat3-pathway-inhibitor-that-exhibits-potent-in-vitro-and-in-vivo-efficacy-against-pancreatic-cancer
  75. www.nature.com www.nature.com
    Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress
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    nature.com/articles/s42255-020-00325-z
  76. Sep 2020
  77. academic.oup.com academic.oup.com
    Chaperone-mediated autophagy governs progression of papillary thyroid carcinoma via PPARγ-SDF1/CXCR4 signaling
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    academic.oup.com/jcem/article/105/10/dgaa366/5859150
  78. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer
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    pubmed.ncbi.nlm.nih.gov/32927276/