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Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.cmet.2025.10.003
  
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sciencedirect.com/science/article/pii/S1550413125004371
Aug 2025
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A fungal chromatin remodeler drives transcription by establishing an open chromatin architecture and activated histone environment

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116169
  
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sciencedirect.com/science/article/pii/S2211124725009404
May 2025
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Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq

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1. scibot 19 May 2025
  
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  DOI: 10.1038/s41596-025-01145-9
  
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nature.com/articles/s41596-025-01145-9
Feb 2025
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TGF-β signaling controls neural crest developmental plasticity via SMAD2/3

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1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.018
  
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sciencedirect.com/science/article/pii/S1534580725000590
Jun 2024
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Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue

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1. scibot 30 Jun 2024
  
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  DOI: 10.1038/s41596-024-01013-y
  
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link.springer.com/article/10.1038/s41596-024-01013-y
May 2024
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Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer

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1. scibot 30 May 2024
  
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  DOI: 10.1002/ctm2.1692
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11131357/
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Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging

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1. scibot 08 May 2024
  
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  DOI: 10.1016/j.isci.2024.109708
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11066433/
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Mitochondrial clearance and increased HSF-1 activity are coupled to promote longevity in fasted Caenorhabditis elegans

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  DOI: 10.1016/j.isci.2024.109834
  
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52.53.155.43/c3b2b2336037431417a6d40cca0ac9967aeadc36/PIIS2589004224010563-html.html
Apr 2024
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Detection of newly synthesized RNA reveals transcriptional reprogramming during ZGA and a role of Obox3 in totipotency acquisition

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1. scibot 16 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114118
  
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sciencedirect.com/science/article/pii/S2211124724004467
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Intratumor microbiome-derived butyrate promotes lung cancer metastasis

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  DOI: 10.1016/j.xcrm.2024.101488
  
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  DOI: 10.1016/j.xcrm.2024.101488
  
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sciencedirect.com/science/article/pii/S2666379124001344
Jan 2024
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Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation

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1. scibot 25 Jan 2024
  
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  DOI: 10.1016/j.molcel.2024.01.002
  
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sciencedirect.com/science/article/pii/S1097276524000030
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Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

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1. scibot 06 Jan 2024
  
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  DOI: 10.1016/j.cmet.2023.12.010
  
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sciencedirect.com/science/article/pii/S1550413123004618
Dec 2023
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Nano-CUT&Tag for multimodal chromatin profiling at single-cell resolution

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1. scibot 29 Dec 2023
  
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  RRID:AB_2828007
  
  DOI: 10.1038/s41596-023-00932-6
  
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nature.com/articles/s41596-023-00932-6
Nov 2023
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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.xcrm.2023.101286
  
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sciencedirect.com/science/article/pii/S2666379123004809
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nuclear miR-150 enhances hepatic lipid accumulation by targeting RNA transcripts overlapping the PLIN2 promoter

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1. scibot 23 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107837
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10509351/
Apr 2023
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SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112323
  
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sciencedirect.com/science/article/pii/S2211124723003340
Mar 2023
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Chidamide suppresses adipogenic differentiation of bone marrow derived mesenchymal stem cells via increasing REEP2 expression

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1. scibot 09 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106221
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9985040/
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Linking chromatin acylation mark-defined proteome and genome in living cells

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.cell.2023.02.007
  
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sciencedirect.com/science/article/pii/S0092867423001095
Nov 2022
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FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

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1. scibot 03 Nov 2022
  
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  DOI: 10.1126/sciadv.abq4831
  
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science.org/doi/10.1126/sciadv.abq4831
Oct 2022
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FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

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1. scibot 07 Oct 2022
  
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  DOI: 10.1126/sciadv.abq4831
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9491713/
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Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells

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  DOI: 10.1016/j.devcel.2022.09.006
  
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sciencedirect.com/science/article/pii/S1534580722006360
Sep 2022
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A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility

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1. scibot 03 Sep 2022
  
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  DOI: 10.1016/j.cell.2022.07.026
  
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sciencedirect.com/science/article/pii/S0092867422009795
May 2022
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Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts

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1. scibot 19 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110821
  
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sciencedirect.com/science/article/pii/S2211124722005927
Feb 2022
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Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation

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  DOI: 10.1016/j.celrep.2022.110391
  
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sciencedirect.com/science/article/pii/S2211124722001127
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SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network

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1. scibot 04 Feb 2022
  
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  DOI: 10.1016/j.ebiom.2022.103861
  
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sciencedirect.com/science/article/pii/S2352396422000457
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Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility

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  DOI: 10.1016/j.neuron.2021.12.034
  
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sciencedirect.com/science/article/pii/S0896627321010898
Sep 2021
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Comparison of Histone H3K4me3 between IVF and ICSI Technologies and between Boy and Girl Offspring

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1. scibot 04 Sep 2021
  
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  DOI: 10.3390/ijms22168574
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8395251/
May 2021
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Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.12.009
  
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sciencedirect.com/science/article/pii/S1934590920305932
Apr 2021
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Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells

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1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.04.005
  
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sciencedirect.com/science/article/pii/S1074761321001679
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Tau seeds are subject to aberrant modifications resulting in distinct signatures

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109037
  
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sciencedirect.com/science/article/pii/S2211124721003533
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Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

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1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.07.008
  
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sciencedirect.com/science/article/pii/S153561082030369X
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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

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  DOI: 10.1016/j.celrep.2021.108994
  
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sciencedirect.com/science/article/pii/S2211124721003089
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The connectome of neural crest enhancers reveals regulatory features of signaling systems

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1. scibot 14 Apr 2021
  
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  DOI: 10.1016/j.devcel.2021.03.024
  
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sciencedirect.com/science/article/pii/S1534580721002641
Feb 2021
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Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

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1. scibot 28 Feb 2021
  
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  DOI: 10.1016/j.celrep.2020.108621
  
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sciencedirect.com/science/article/pii/S2211124720316107