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N(6)-methyladenosine modification of RNA is regulated by senataxin and E6 to control HPV replication

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  DOI: 10.1016/j.celrep.2025.116828
  
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Exploiting the polypharmacology of alectinib for synergistic RNA splicing disruption with RBM39 degraders

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Jan 2026
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RNA-guided STAT3 modification fine tunes the epigenetic and epitranscriptomic regulation of CD4 + T helper cell differentiation during non-small cell lung cancer (NSCLC)

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  DOI: 10.1007/s12032-025-03230-1
  
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link.springer.com/article/10.1007/s12032-025-03230-1
Oct 2025
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Dcr1 senses R-loops for RNAPII termination at sites of replication stress and repair pathway choice

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1. scibot 29 Oct 2025
  
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BET family BRD3 initiates DSB-induced chromatin remodeling with TIP60 to promote R-loop-mediated HR

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The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids

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Targeting the UFL1-PARP1 axis amplifies anti-tumor immunity

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Apr 2025
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ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition

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52.53.155.43/1d7f3a53d05f85c55a541cebaae421bfbc1ec25f/PDF-html.html
Feb 2025
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SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

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Jan 2025
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Functional conservation and divergence of arabidopsis VENOSA4 and human SAMHD1 in DNA repair

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  DOI: 10.1016/j.heliyon.2024.e41019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11720913/
Dec 2024
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DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance

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Oct 2024
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Long noncoding RNA TUG1 regulates smooth muscle cell differentiation via KLF4-myocardin axis

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1. scibot 02 Oct 2024
  
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  DOI: 10.1152/ajpcell.00275.2023
  
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Sep 2024
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

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May 2024
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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

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Jan 2024
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ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.12.018
  
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Oct 2023
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The splicing factor DHX38 enables retinal development through safeguarding genome integrity

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1. scibot 14 Oct 2023
  
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Aug 2023
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Small molecule targeting of transcription-replication conflict for selective chemotherapy

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.chembiol.2023.07.001
  
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Jul 2023
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Inhibition of nucleolar transcription by oxaliplatin involves ATM/ATR kinase signaling

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Jun 2023
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Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability

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May 2023
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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

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Mar 2023
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ATXN3 controls DNA replication and transcription by regulating chromatin structure

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  DOI: 10.1093/nar/gkad212
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad212/7086677
Nov 2022
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Metabolic regulation by p53 prevents R-loop-associated genomic instability

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Oct 2022
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DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation

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TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch

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p300/CBP sustains Polycomb silencing by non-enzymatic functions

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Jul 2022
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Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5

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Jun 2022
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cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

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ncbi.nlm.nih.gov/pmc/articles/PMC9194172/
May 2022
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Chl1 coordinates with H3K9 methyltransferase Clr4 to reduce the accumulation of RNA-DNA hybrids and maintain genome stability

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Mar 2022
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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments

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Feb 2022
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RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair

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Mar 2021
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MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

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Jan 2021
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DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

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1. scibot 05 Jan 2021
  
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  Anti-DNA-RNA Hybrid Antibody, clone S9.6
  
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Sep 2020
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SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells

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1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108184
  
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