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A CHK1-mediated phosphorylation switch suppresses human Topoisomerase 1-associated genomic instability

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s44318-026-00783-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13270093/
Jun 2026
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Co-transcriptional splicing regulation in FLC mediated by AtCDC5 and AtSYF2 regulates plant flowering

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1. scibot 14 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117508
  
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sciencedirect.com/science/article/pii/S2211124726005863
Apr 2026
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Alu repeat-containing RNAs spatially organize actively transcribed genomic regions around nuclear speckles

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.molcel.2026.03.031
  
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sciencedirect.com/science/article/pii/S1097276526002078
Mar 2026
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Multi-omic analyses reveal a differential contribution of chromatin-associated PP1 holoenzymes to mitotic exit and G1 re-establishment

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.016
  
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2026.02.21.707204.full-html.html

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54.241.53.176/15567438d95e9a9b4b01123f2967397938de8973/2026.02.21.707204.full-html.html
Feb 2026
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RAD51C-XRCC3 complex regulates FANCM-mediated R-loop resolution to safeguard genome integrity

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1. scibot 24 Feb 2026
  
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  DOI: 10.1126/sciadv.aea5932
  
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science.org/doi/10.1126/sciadv.aea5932
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RAD51C-XRCC3 complex regulates FANCM-mediated R-loop resolution to safeguard genome integrity

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1. scibot 24 Feb 2026
  
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  DOI: 10.1126/sciadv.aea5932
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12922753/
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STAT4 mediated modulation of T–B cell interactions profiling: enhances antitumor immunity in non-small cell lung cancer (NSCLC)

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1. scibot 19 Feb 2026
  
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  DOI: 10.1007/s11033-026-11558-8
  
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link.springer.com/article/10.1007/s11033-026-11558-8
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STAT2 Mediated Epigenetic and Epitranscriptomic Regulation of CD4+ T Helper Cell Differentiation in Non-Small Cell Lung Cancer (NSCLC)

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1. scibot 06 Feb 2026
  
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  DOI: 10.1111/imm.70121
  
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onlinelibrary.wiley.com/doi/10.1111/imm.70121
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C9orf72 hexanucleotide repeat RNA drives transcriptional dysregulation through genome-wide DNA:RNA hybrid G-quadruplexes

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1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.neuron.2025.12.005
  
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sciencedirect.com/science/article/pii/S0896627325009328
Jan 2026
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MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.019
  
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sciencedirect.com/science/article/pii/S0092867425014321
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N(6)-methyladenosine modification of RNA is regulated by senataxin and E6 to control HPV replication

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1. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116828
  
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sciencedirect.com/science/article/pii/S2211124725016006
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Exploiting the polypharmacology of alectinib for synergistic RNA splicing disruption with RBM39 degraders

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116784
  
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sciencedirect.com/science/article/pii/S2211124725015566
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RNA-guided STAT3 modification fine tunes the epigenetic and epitranscriptomic regulation of CD4 + T helper cell differentiation during non-small cell lung cancer (NSCLC)

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1. scibot 06 Jan 2026
  
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  DOI: 10.1007/s12032-025-03230-1
  
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link.springer.com/article/10.1007/s12032-025-03230-1
Oct 2025
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Dcr1 senses R-loops for RNAPII termination at sites of replication stress and repair pathway choice

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.10.004
  
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sciencedirect.com/science/article/pii/S1097276525008202
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BET family BRD3 initiates DSB-induced chromatin remodeling with TIP60 to promote R-loop-mediated HR

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116461
  
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sciencedirect.com/science/article/pii/S221112472501232X
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The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids

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1. scibot 22 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116438
  
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sciencedirect.com/science/article/pii/S2211124725012094
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Targeting the UFL1-PARP1 axis amplifies anti-tumor immunity

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116433
  
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sciencedirect.com/science/article/pii/S2211124725012045
Apr 2025
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ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.04.004
  
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sciencedirect.com/science/article/pii/S1097276525003077
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PDF-html.html

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1. scibot 13 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112408
  
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52.53.155.43/1d7f3a53d05f85c55a541cebaae421bfbc1ec25f/PDF-html.html
Feb 2025
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SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.molcel.2025.01.008
  
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sciencedirect.com/science/article/pii/S1097276525000425
Jan 2025
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Functional conservation and divergence of arabidopsis VENOSA4 and human SAMHD1 in DNA repair

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1. scibot 25 Jan 2025
  
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  DOI: 10.1016/j.heliyon.2024.e41019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11720913/
Dec 2024
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DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.029
  
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sciencedirect.com/science/article/pii/S1097276524009547
Oct 2024
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Long noncoding RNA TUG1 regulates smooth muscle cell differentiation via KLF4-myocardin axis

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1. scibot 02 Oct 2024
  
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  DOI: 10.1152/ajpcell.00275.2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10635660/
Sep 2024
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.014
  
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sciencedirect.com/science/article/pii/S009286742400905X
May 2024
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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114214
  
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sciencedirect.com/science/article/pii/S2211124724005424
Jan 2024
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ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.12.018
  
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sciencedirect.com/science/article/pii/S1534580723006986
Oct 2023
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The splicing factor DHX38 enables retinal development through safeguarding genome integrity

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.108103
  
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sciencedirect.com/science/article/pii/S2589004223021806
Aug 2023
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Small molecule targeting of transcription-replication conflict for selective chemotherapy

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  DOI: 10.1016/j.chembiol.2023.07.001
  
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sciencedirect.com/science/article/pii/S2451945623002210
Jul 2023
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Inhibition of nucleolar transcription by oxaliplatin involves ATM/ATR kinase signaling

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.chembiol.2023.06.010
  
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sciencedirect.com/science/article/abs/pii/S2451945623001885
Jun 2023
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Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability

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1. scibot 09 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.015
  
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sciencedirect.com/science/article/pii/S1097276523003714
May 2023
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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

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1. scibot 20 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.035
  
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sciencedirect.com/science/article/pii/S0092867423004695
Mar 2023
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ATXN3 controls DNA replication and transcription by regulating chromatin structure

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1. scibot 29 Mar 2023
  
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  DOI: 10.1093/nar/gkad212
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad212/7086677
Nov 2022
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Metabolic regulation by p53 prevents R-loop-associated genomic instability

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1. scibot 03 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111568
  
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sciencedirect.com/science/article/pii/S2211124722014292
Oct 2022
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DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111526
  
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sciencedirect.com/science/article/pii/S2211124722013821
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TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch

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1. scibot 20 Oct 2022
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.molcel.2022.09.026
  
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sciencedirect.com/science/article/pii/S1097276522009364
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p300/CBP sustains Polycomb silencing by non-enzymatic functions

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1. scibot 07 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.005
  
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sciencedirect.com/science/article/pii/S1097276522008942
Jul 2022
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Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111067
  
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sciencedirect.com/science/article/pii/S2211124722008658
Jun 2022
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cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

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1. scibot 17 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104404
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9194172/
May 2022
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Chl1 coordinates with H3K9 methyltransferase Clr4 to reduce the accumulation of RNA-DNA hybrids and maintain genome stability

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1. scibot 13 May 2022
  
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  DOI: 10.1016/j.isci.2022.104313
  
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sciencedirect.com/science/article/pii/S2589004222005843
Mar 2022
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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments

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1. scibot 09 Mar 2022
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.celrep.2022.110411
  
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sciencedirect.com/science/article/pii/S2211124722001358
Feb 2022
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RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair

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1. scibot 02 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110335
  
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sciencedirect.com/science/article/pii/S2211124722000511
Mar 2021
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MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

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1. scibot 01 Mar 2021
  
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  DOI: 10.1016/j.ccell.2020.12.010
  
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sciencedirect.com/science/article/pii/S1535610820306589
Jan 2021
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DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

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1. scibot 05 Jan 2021
  
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  Anti-DNA-RNA Hybrid Antibody, clone S9.6
  
  DOI: 10.1016/j.celrep.2020.108569
  
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sciencedirect.com/science/article/pii/S2211124720315588
Sep 2020
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SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells

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1. scibot 25 Sep 2020
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.celrep.2020.108184
  
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sciencedirect.com/science/article/pii/S2211124720311736