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Multiplex base editing of BCL11A regulatory elements to treat sickle cell disease

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1. scibot 27 Sep 2025
  
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  RRID:AB_2868815
  
  DOI: 10.1016/j.xcrm.2025.102376
  
  Resource: (BD Biosciences Cat# 345789, RRID:AB_2868815)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2666379125004495
Jun 2025
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Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells

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1. scibot 04 Jun 2025
  
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  RRID:AB_2868815
  
  DOI: 10.1016/j.xcrm.2025.102157
  
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sciencedirect.com/science/article/pii/S2666379125002307
Nov 2024
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A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells

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1. scibot 14 Nov 2024
  
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  RRID:AB_2868815
  
  DOI: 10.1016/j.xcrm.2024.101823
  
  Resource: (BD Biosciences Cat# 345789, RRID:AB_2868815)
  
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sciencedirect.com/science/article/pii/S2666379124005949
Dec 2023
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Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells.

2
1. scibot 21 Dec 2023
  
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  RRID: AB_2868815
  
  DOI: 10.1016/j.ymthe.2023.11.020
  
  Resource: (BD Biosciences Cat# 345789, RRID:AB_2868815)
  
  Curator: @evieth
  
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2. scibot 21 Dec 2023
  
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  RRID:AB_2868815
  
  DOI: 10.1016/j.ymthe.2023.11.020
  
  Resource: (BD Biosciences Cat# 345789, RRID:AB_2868815)
  
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sciencedirect.com/science/article/pii/S1525001623006214
Oct 2022
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Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells

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1. scibot 15 Oct 2022
  
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  RRID:AB_2868815
  
  DOI: 10.1016/j.stem.2022.09.001
  
  Resource: (BD Biosciences Cat# 345789, RRID:AB_2868815)
  
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sciencedirect.com/science/article/pii/S1934590922003782
Jun 2022
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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

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1. scibot 01 Jun 2022
  
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  RRID:AB_2868815
  
  DOI: 10.1016/j.cell.2022.04.039
  
  Resource: (BD Biosciences Cat# 345789, RRID:AB_2868815)
  
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sciencedirect.com/science/article/pii/S0092867422005372
May 2021
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BAR-Seq clonal tracking of gene-edited cells

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1. scibot 29 May 2021
  
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  RRID:AB_2868815
  
  DOI: 10.1038/s41596-021-00529-x
  
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nature.com/articles/s41596-021-00529-x