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Apr 2026
www.nature.com www.nature.com

ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbances

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  DOI: 10.1038/s41420-026-03027-9
  
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nature.com/articles/s41420-026-03027-9
Mar 2026
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Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia

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  DOI: 10.1016/j.celrep.2026.117185
  
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sciencedirect.com/science/article/pii/S2211124726002639
54.241.53.176 54.241.53.176

1-s2.0-S2589004226007388-main-html.html

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54.241.53.176/ded82c53724b10b4260d5a6de7bc7457f5435ac0/1-s2.0-S2589004226007388-main-html.html
Jan 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004225028585-main-html.html

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  DOI: 10.1016/j.isci.2025.114597
  
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54.241.53.176/afe90d5c83594271a2733149652de6adb4aa341e/1-s2.0-S2589004225028585-main-html.html
Nov 2025
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Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia

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  DOI: 10.1016/j.cell.2025.10.028
  
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sciencedirect.com/science/article/pii/S0092867425012334
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic evaluation of GAPs and GEFs identifies a targetable dependency for hematopoietic malignancies

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  DOI: 10.1158/2159-8290.CD-25-0299
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12427560/
Jul 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

A spheroid model that recapitulates the protective role of the lymph node microenvironment and serves as a platform for drug testing in chronic lymphocytic leukemia

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  DOI: 10.1002/hem3.70170
  
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onlinelibrary.wiley.com/doi/10.1002/hem3.70170
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Efficacy of NAMPT inhibition in T-cell acute lymphoblastic leukemia

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  DOI: 10.1371/journal.pone.0324443
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12173385/
Apr 2025
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Halting hepatocellular carcinoma: Identifying intercellular crosstalk in HBV-driven disease

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  DOI: 10.1016/j.celrep.2025.115457
  
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sciencedirect.com/science/article/pii/S2211124725002281
Dec 2024
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Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumors

1
1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101878
  
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sciencedirect.com/science/article/pii/S2666379124006499
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EAF2 deficiency attenuates autoimmune disease in Faslpr mice by modulating B cell activation and apoptosis

1
1. scibot 19 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111220
  
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sciencedirect.com/science/article/pii/S2589004224024453
Jul 2024
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BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114403
  
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sciencedirect.com/science/article/pii/S2211124724007319
May 2024
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SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis

1
1. scibot 23 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.023
  
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sciencedirect.com/science/article/pii/S153458072400296X
Apr 2024
aacrjournals.org aacrjournals.org

miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress

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1. scibot 19 Apr 2024
  
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  DOI: 10.1158/1541-7786.MCR-23-0676
  
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aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
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Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114065
  
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sciencedirect.com/science/article/pii/S2211124724003930
Dec 2023
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Small-molecule TIP60 inhibitors enhance regulatory T cell induction through TIP60-P300 acetylation crosstalk

1
1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108491
  
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sciencedirect.com/science/article/pii/S2589004223025683
Sep 2023
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Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

1
1. scibot 16 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113098
  
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sciencedirect.com/science/article/pii/S2211124723011099
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection

1
1. scibot 31 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107552
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10460994/
Jun 2023
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Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

1
1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.cmet.2023.05.007
  
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sciencedirect.com/science/article/pii/S1550413123001845
Apr 2023
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SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways

1
1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106621
  
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sciencedirect.com/science/article/pii/S2589004223006983
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

1
1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.02.010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SETD2 haploinsufficiency enhances germinal center-associated AICDA somatic hypermutation to drive B cell lymphomagenesis

1
1. scibot 07 Jan 2023
  
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  DOI: 10.1158/2159-8290.CD-21-1514
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9262862/
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P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy

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  DOI: 10.1158/2326-6066.CIR-21-0691
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9250641/
Dec 2022
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A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage

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1. scibot 30 Dec 2022
  
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  DOI: 10.7554/eLife.80277
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9797186/
Sep 2022
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.ccell.2022.08.016
  
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sciencedirect.com/science/article/pii/S1535610822003804
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cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells

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  DOI: 10.1016/j.celrep.2022.111373
  
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sciencedirect.com/science/article/pii/S2211124722012050
Jun 2022
52.53.155.43 52.53.155.43

cd-21-1514-html.html

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1. scibot 30 Jun 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1514
  
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  DOI: 10.1158/2159-8290.cd-21-1514
  
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  DOI: 10.1158/2159-8290.cd-21-1514
  
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52.53.155.43/30b9574de57b2e4ccfd380c8f4f8e4cb5eb75f43/cd-21-1514-html.html
May 2022
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A MACS protocol for purification of untouched germinal center B cells from unimmunized or germinal center-induced mice

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  DOI: 10.1016/j.xpro.2022.101388
  
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sciencedirect.com/science/article/pii/S2666166722002684
Apr 2022
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Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis

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  DOI: 10.1016/j.cell.2022.03.030
  
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sciencedirect.com/science/article/pii/S0092867422003403
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NADPH metabolism determines the leukemogenic capacity and drug resistance of AML cells

1
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  DOI: 10.1016/j.celrep.2022.110607
  
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sciencedirect.com/science/article/pii/S2211124722003552
Mar 2022
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML

1
1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110481
  
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sciencedirect.com/science/article/pii/S2211124722002145
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Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling

1
1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.molcel.2022.02.007
  
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sciencedirect.com/science/article/pii/S1097276522001125
Feb 2022
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An oncogenic enhancer encodes selective selenium dependency in AML

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1. scibot 02 Feb 2022
  
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  DOI: 10.1016/j.stem.2022.01.003
  
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sciencedirect.com/science/article/pii/S1934590922000030
Dec 2021
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Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence

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1. scibot 18 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103558
  
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  SciCrunch record: RRID:AB_2868885
  
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  RRID:AB_2868885
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sciencedirect.com/science/article/pii/S2589004221015285
Aug 2021
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Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

1
1. scibot 25 Aug 2021
  
  in Public
  
  RRID:AB_2868885
  
  DOI: 10.1016/j.celrep.2021.109568
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2868885
  
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  RRID:AB_2868885
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sciencedirect.com/science/article/pii/S2211124721010020
elifesciences.org elifesciences.org

HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:AB_2868885
  
  DOI: 10.7554/eLife.64148
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2868885
  
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  RRID:AB_2868885
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elifesciences.org/articles/64148
Jul 2021
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MYC deficiency impairs the development of effector/memory T lymphocytes

1
1. scibot 07 Jul 2021
  
  in Public
  
  RRID:AB_2868885
  
  DOI: 10.1016/j.isci.2021.102761
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2868885
  
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  RRID:AB_2868885
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sciencedirect.com/science/article/pii/S258900422100729X
May 2021
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Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection

1
1. scibot 26 May 2021
  
  in Public
  
  RRID:AB_2868885
  
  DOI: 10.1016/j.celrep.2021.109160
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2868885
  
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sciencedirect.com/science/article/pii/S2211124721005027
Apr 2021
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Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

1
1. scibot 21 Apr 2021
  
  in Public
  
  Annexin V-APC
  
  DOI: 10.1016/j.celrep.2021.109010
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2868885
  
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  RRIDCUR:Missing RRID:AB_2868885
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sciencedirect.com/science/article/pii/S2211124721003247
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Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies

1
1. scibot 17 Apr 2021
  
  in Public
  
  Annexin V
  
  DOI: 10.1016/j.ccell.2020.05.004
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
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  SciCrunch record: RRID:AB_2868885
  
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  RRID:AB_2868885 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610820302543
Feb 2021
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SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:AB_2868885
  
  DOI: 10.1016/j.celrep.2021.108758
  
  Resource: (BD Biosciences Cat# 550475, RRID:AB_2868885)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2868885
  
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  RRIDCUR:Validated RRID:AB_2868885
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sciencedirect.com/science/article/pii/S2211124721000711