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Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

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1. scibot 16 Jun 2026
  
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  RRID:AB_2869822
  
  DOI: 10.1126/sciadv.aee0517
  
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science.org/doi/10.1126/sciadv.aee0517
Nov 2025
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.004
  
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sciencedirect.com/science/article/pii/S1074761325004340
Aug 2025
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High-dose ascorbic acid selectively induces pyroptosis in LKB1-deficient lung cancer and sensitizes immunotherapy

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1. scibot 19 Aug 2025
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.xcrm.2025.102291
  
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sciencedirect.com/science/article/pii/S2666379125003647
Jul 2025
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Distinct follicular T cell subsets regulate lymphoma progression and outcomes

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1. scibot 03 Jul 2025
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.ccell.2025.06.013
  
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sciencedirect.com/science/article/pii/S1535610825002636
Jun 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225009769-main-html.html

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1. scibot 11 Jun 2025
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.isci.2025.112715
  
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2. scibot 11 Jun 2025
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.isci.2025.112715
  
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52.53.155.43/cc707e459b029b000ac6efbce15180cbbd7d6f19/PDF-html.html
May 2025
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.03.036
  
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sciencedirect.com/science/article/pii/S1535610825001370
Mar 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti-Tumor Effector Cytotoxic T Cells

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1. scibot 13 Mar 2025
  
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  DOI: 10.1002/advs.202410241
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202410241
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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1. scibot 26 Feb 2025
  
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  RRID: AB_2869822
  
  DOI: 10.1084/jem.20231486
  
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  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
Dec 2024
www.cell.com www.cell.com

Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

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1. scibot 29 Dec 2024
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.ccell.2024.12.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
Mar 2024
www.cell.com www.cell.com

Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer

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1. scibot 15 Mar 2024
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.cell.2024.02.022
  
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cell.com/cell/fulltext/S0092-8674(24)00224-1
Feb 2024
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Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

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1. scibot 06 Feb 2024
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.cmet.2024.01.005
  
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sciencedirect.com/science/article/pii/S1550413124000068
Apr 2023
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Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response

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1. scibot 20 Apr 2023
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.celrep.2023.112186
  
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sciencedirect.com/science/article/pii/S2211124723001973
Jan 2023
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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

1
1. scibot 19 Jan 2023
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.ccell.2022.12.007
  
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sciencedirect.com/science/article/pii/S1535610822005931
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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

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1. scibot 12 Jan 2023
  
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  RRID:AB_2869822
  
  DOI: 10.1016/j.immuni.2022.12.006
  
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sciencedirect.com/science/article/pii/S1074761322006422