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TCR origin and specificity to environmental or self-antigens on distinct antigen-presenting cells determine peripheral Treg cell differentiation

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1. scibot 30 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.07.001
  
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sciencedirect.com/science/article/pii/S1074761326002773
Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tobemstomig, a novel bispecific antibody, preferentially blocks PD-1 and LAG-3 on CD8 TILs to expand stem-like T-cells for sustained tumor control

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0207
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13347385/
Jun 2026
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Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.016
  
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sciencedirect.com/science/article/pii/S107476132600227X
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A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.015
  
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sciencedirect.com/science/article/pii/S1074761326002268
May 2026
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NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.immuni.2026.03.027
  
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sciencedirect.com/science/article/pii/S107476132600138X
Apr 2026
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MAIT cells egress the thymus at several maturation stages with selective capacity to seed different tissues

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.024
  
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sciencedirect.com/science/article/pii/S1074761326001354
Mar 2026
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Tuft cells promote reactivation of memory Th2 cells and are required for protective immunity to intestinal helminth re-infection

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.022
  
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sciencedirect.com/science/article/pii/S1074761326000920
Feb 2026
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Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.003
  
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sciencedirect.com/science/article/pii/S1074761326000026
Nov 2025
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Urothelial collective-gliding response acts as a toll-like receptor 4-associated defense mechanism

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1. scibot 23 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113553
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12508895/
Oct 2025
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Urothelial collective-gliding response acts as a toll-like receptor 4-associated defense mechanism

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1. scibot 02 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113553
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12508895/
Jul 2025
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APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

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1. scibot 02 Jul 2025
  
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  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Jun 2025
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The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.cell.2025.05.029
  
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sciencedirect.com/science/article/pii/S0092867425006166
Mar 2025
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Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.chom.2025.03.004
  
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sciencedirect.com/science/article/pii/S1931312825000873
Feb 2025
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Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.cell.2025.01.028
  
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sciencedirect.com/science/article/pii/S0092867425000972
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In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.immuni.2025.01.009
  
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sciencedirect.com/science/article/pii/S1074761325000342
Dec 2024
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.10.010
  
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sciencedirect.com/science/article/pii/S1074761324004904
Jul 2024
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Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine

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1. scibot 11 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114490
  
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sciencedirect.com/science/article/pii/S2211124724008192
Jun 2024
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STING orchestrates the neuronal inflammatory stress response in multiple sclerosis

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.031
  
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sciencedirect.com/science/article/pii/S0092867424005762
May 2024
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Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.022
  
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sciencedirect.com/science/article/pii/S1074761324002279
Apr 2023
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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.01.033
  
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sciencedirect.com/science/article/pii/S1074761323000456
Jan 2023
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GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.12.009
  
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sciencedirect.com/science/article/pii/S1074761322006458
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62

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1. scibot 12 Jul 2022
  
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  DOI: 10.1158/1541-7786.MCR-21-0560
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
Jun 2022
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Interspecies commensal interactions have nonlinear impacts on host immunity

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1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.chom.2022.05.004
  
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sciencedirect.com/science/article/pii/S1931312822002645
Jun 2021
www.cell.com www.cell.com

Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

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1. scibot 24 Jun 2021
  
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  DOI: 10.1016/j.cell.2021.05.020
  
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cell.com/cell/fulltext/S0092-8674(21)00650-4
May 2021
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An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.immuni.2020.10.024
  
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sciencedirect.com/science/article/pii/S1074761320304659
Feb 2021
www.cell.com www.cell.com

Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.chom.2020.12.002
  
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cell.com/cell-host-microbe/abstract/S1931-3128(20)30664-8
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Infection trains the host for microbiota-enhanced resistance to pathogens

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1. scibot 09 Feb 2021
  
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  DOI: 10.1016/j.cell.2020.12.011
  
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sciencedirect.com/science/article/pii/S0092867420316810