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PFKFB3 inhibition dictates the adaptive responses and cell fates in tumor cells

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1. scibot 08 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.117768
  
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sciencedirect.com/science/article/pii/S2589004226031494
Sep 2026
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PHPT1/Ocnus negatively regulates the JAK/STAT pathway to control cell survival

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  DOI: 10.1016/j.isci.2026.117537
  
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sciencedirect.com/science/article/pii/S2589004226029160
Aug 2026
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Munc13 serves as a molecular filter for SNARE sorting and assembly in active zone condensates

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1. scibot 21 Aug 2026
  
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  DOI: 10.1073/pnas.2529572123
  
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pnas.org/doi/abs/10.1073/pnas.2529572123
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Development of a matrix-supported 2.5-dimensional co-culture model: an in vitro platform for studying liver cell interaction and disease mechanisms

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1. scibot 14 Aug 2026
  
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  DOI: 10.1039/d6ra05249e
  
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dx.doi.org/10.1039/d6ra05249e
Jul 2026
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FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer’s disease pathology

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  DOI: 10.1038/s44318-026-00818-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13324857/
May 2026
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Farnesylation-driven KRAS phase separation promotes colon tumor growth

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  DOI: 10.1016/j.cell.2026.05.002
  
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sciencedirect.com/science/article/pii/S0092867426005192
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Alphaviral non-structural protein-host RBP co-condensation as a mechanism to sustain virus replication

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1. scibot 27 May 2026
  
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  DOI: 10.1016/j.molcel.2026.04.022
  
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sciencedirect.com/science/article/pii/S1097276526002765
Apr 2026
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Mechanosensory channels mediate ER Ca2+ transients to trigger assembly of autophagosome initiation sites for degradation of ER subdomains

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1. scibot 09 Apr 2026
  
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sciencedirect.com/science/article/pii/S1097276526001589
Feb 2026
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A lineage-specific selective autophagy receptor module mediates P-body turnover

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.devcel.2026.01.017
  
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sciencedirect.com/science/article/pii/S1534580726000407
Jan 2026
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Impaired VLCFA-peroxisome-mediated intestinal epithelial repair causes gastrointestinal sequelae of long COVID

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  DOI: 10.1016/j.devcel.2025.12.003
  
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sciencedirect.com/science/article/pii/S1534580725007476
Dec 2025
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Chilling stress suppresses plant reproduction through modulating BZR1 translation efficiency by CSP2

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1. scibot 25 Dec 2025
  
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  DOI: 10.1016/j.cub.2025.11.074
  
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sciencedirect.com/science/article/pii/S096098222501615X
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Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.devcel.2025.11.001
  
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sciencedirect.com:5037/science/article/pii/S1534580725006938
Oct 2025
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Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance

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1. scibot 25 Oct 2025
  
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  DOI: 10.1016/j.cell.2025.09.029
  
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sciencedirect.com/science/article/pii/S0092867425011298
Aug 2025
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RNA Pol II inhibition activates cell death independently from the loss of transcription

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  DOI: 10.1016/j.cell.2025.07.034
  
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cell.com/cell/abstract/S0092-8674(25)00856-6
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A mechano-resistance mechanism in skin adapts to terrestrial locomotion

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  DOI: 10.1016/j.cell.2025.07.012
  
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cell.com/cell/abstract/S0092-8674(25)00801-3
Jun 2025
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1-s2.0-S2589004225011927-main-html.html

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1. scibot 18 Jun 2025
  
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52.53.155.43/90b235b4bfe3af1e677411c1844e709bf822d451/1-s2.0-S2589004225011927-main-html.html
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SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115843
  
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sciencedirect.com/science/article/pii/S221112472500614X
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Astrocytic modulation of GABA transmission in the VTA limits progression of anxiety- and depression-like behaviors in adult mice

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115824
  
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sciencedirect.com/science/article/pii/S2211124725005959
May 2025
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Phase transition of WTAP regulates m6A modification of interferon-stimulated genes

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1. scibot 31 May 2025
  
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  DOI: 10.7554/eLife.100601
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12113268/
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Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115766
  
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sciencedirect.com/science/article/pii/S2211124725005376
Apr 2025
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RAF1 kinase contributes to autophagic lysosome reformation

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  DOI: 10.1016/j.celrep.2025.115490
  
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sciencedirect.com/science/article/pii/S221112472500261X
Dec 2024
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Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis

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sciencedirect.com/science/article/pii/S2211124724014116
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Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles

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1. scibot 12 Dec 2024
  
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sciencedirect.com/science/article/pii/S1097276524009201
Oct 2024
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Jawbone periosteum-derived cells with high osteogenic potential controlled by R-spondin 3

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1. scibot 02 Oct 2024
  
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  DOI: 10.1096/fj.202400988RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400988RR
Sep 2024
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C9orf72 poly-PR forms anisotropic condensates causative of nuclear TDP-43 pathology

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1. scibot 26 Sep 2024
  
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Aug 2024
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The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network

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1. scibot 20 Aug 2024
  
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sciencedirect.com/science/article/pii/S2211124724009677
May 2024
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Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release

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1. scibot 19 May 2024
  
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  DOI: 10.1126/sciadv.adi7024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11100570/
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Bidirectional regulation of levodopa-induced dyskinesia by a specific neural ensemble in globus pallidus external segment

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  DOI: 10.1016/j.xcrm.2024.101566
  
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sciencedirect.com/science/article/pii/S2666379124002581
Jan 2024
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FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement

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1. scibot 10 Jan 2024
  
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  DOI: 10.1101/2023.10.23.563675
  
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52.53.155.43/c60ff44b398a1a7e11716522ef1a88906101d062/2023.10.23.563675v2.full-html.html
Jul 2023
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RLI2 regulates Arabidopsis female gametophyte and embryo development by facilitating the assembly of the translational machinery

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  DOI: 10.1016/j.celrep.2023.112741
  
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sciencedirect.com/science/article/pii/S2211124723007520
Jan 2023
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DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling

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  DOI: 10.1016/j.celrep.2022.111986
  
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sciencedirect.com/science/article/pii/S2211124722018903
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Engineering probiotic-derived outer membrane vesicles as functional vaccine carriers to enhance immunity against SARS-CoV-2

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  DOI: 10.1016/j.isci.2022.105772
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9729586/
Dec 2022
www.embopress.org www.embopress.org

GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum

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1. scibot 20 Dec 2022
  
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  DOI: 10.15252/embj.2022111513
  
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embopress.org/doi/10.15252/embj.2022111513
Nov 2021
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ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress

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1. scibot 09 Nov 2021
  
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  DOI: 10.1016/j.devcel.2021.10.006
  
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sciencedirect.com/science/article/pii/S1534580721008078
Oct 2021
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Deficiency of ER Ca2+ sensor STIM1 in AgRP neurons confers protection against dietary obesity

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1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109868
  
  Resource: (Proteintech Cat# 26765-1-AP, RRID:AB_2876881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2876881
  
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  RRID:AB_2876881
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RRID:AB_2876881

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scibot

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sciencedirect.com/science/article/pii/S2211124721013358