10 Matching Annotations
  1. Jun 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13196427/
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting leucine-rich repeat kinase 2 overcomes resistance to oncolytic herpes simplex virus-based therapies in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13066370/
  5. Sep 2025
  6. 52.53.155.43 52.53.155.43
    2025.08.28.672006v1.full-html.html
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    52.53.155.43/1c78deaa12ef1065bee04217bb87fcbf90d61c87/2025.08.28.672006v1.full-html.html
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462683/
  9. Mar 2025
  10. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/c83c3399f0f3ceedbbadf4465eff5f081b0ef0bc/PDF-html.html
  11. May 2024
  12. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  13. Dec 2023
  14. elifesciences.org elifesciences.org
    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
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    elifesciences.org/articles/87255
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  16. Sep 2022
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
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    ncbi.nlm.nih.gov/pmc/articles/PMC9472821/
  18. Mar 2021
  19. www.sciencedirect.com www.sciencedirect.com
    Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
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    sciencedirect.com/science/article/pii/S0960982221003055