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STING reprogramming by estrogen promotes neutrophil extracellular trap formation and sex-biased resistance to ADC therapy

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1. scibot 08 Oct 2026
  
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  RRID:AB_2885196
  
  DOI: 10.1016/j.cell.2026.09.031
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
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sciencedirect.com/science/article/pii/S0092867426011335
Mar 2026
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ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei

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1. scibot 20 Mar 2026
  
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  RRID:AB_2885196
  
  DOI: 10.1016/j.molcel.2026.02.012
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
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sciencedirect.com/science/article/pii/S1097276526001267
Feb 2025
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Nucleic-acid-induced ZCCHC3 condensation promotes broad innate immune responses

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1. scibot 21 Feb 2025
  
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  RRID:AB_2885196
  
  DOI: 10.1016/j.molcel.2025.01.027
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
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sciencedirect.com/science/article/pii/S1097276525000619
May 2024
aacrjournals.org aacrjournals.org

TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity

2
1. scibot 23 May 2024
  
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  RRID:AB_2885196
  
  DOI: 10.1158/2159-8290.CD-23-0700
  
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2. scibot 23 May 2024
  
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  RRID:AB_2885196
  
  DOI: 10.1158/2159-8290.CD-23-0700
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2885196
  
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aacrjournals.org/cancerdiscovery/article/14/5/752/745044/TREX1-Inactivation-Unleashes-Cancer-Cell-STING
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling

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1. scibot 01 Feb 2024
  
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  AB_2885196
  
  DOI: 10.1101/2024.01.04.574136
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802300/
Aug 2021
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Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair

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1. scibot 03 Aug 2021
  
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  RRID:AB_2885196
  
  DOI: 10.1016/j.cmet.2021.07.009
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
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sciencedirect.com/science/article/pii/S1550413121003259
Mar 2021
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ER-directed TREX1 limits cGAS activation at micronuclei

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1. scibot 01 Mar 2021
  
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  AB_2885196
  
  DOI: 10.1016/j.molcel.2020.12.037
  
  Resource: (Abcam Cat# ab185228, RRID:AB_2885196)
  
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  SciCrunch record: RRID:AB_2885196
  
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sciencedirect.com/science/article/pii/S1097276520309588