20 Matching Annotations
  1. Mar 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases
    1
    1. scibot 01 Mar 2024
      AdipoGen Life SciencesAG-20B-0014-C100

      DOI: 10.1016/j.celrep.2024.113852

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S2211124724001803
  3. Feb 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Brazilin is a natural product inhibitor of the NLRP3 inflammasome
    1
    1. scibot 08 Feb 2024
      RRID:AB_2885199

      DOI: 10.1016/j.isci.2024.108968

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    sciencedirect.com/science/article/pii/S2589004224001895
  5. Jan 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7
    1
    1. scibot 12 Jan 2024
      RRID:AB_2885199

      DOI: 10.1016/j.xcrm.2023.101310

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    ncbi.nlm.nih.gov/pmc/articles/PMC10772347/
  7. Dec 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
    1
    1. scibot 02 Dec 2023
      RRID:AB_2885199

      DOI: 10.1016/j.xcrm.2023.101245

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    sciencedirect.com/science/article/pii/S2666379123004226
  9. Oct 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway
    1
    1. scibot 27 Oct 2023
      RRID:AB_2885199

      DOI: 10.1016/j.isci.2023.108130

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    ncbi.nlm.nih.gov/pmc/articles/PMC10590863/
  11. Jul 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
    1
    1. scibot 22 Jul 2023
      RRID:AB_2885199

      DOI: 10.1016/j.xcrm.2023.101129

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    sciencedirect.com/science/article/pii/S2666379123002574
  13. Jun 2023
  14. www.sciencedirect.com www.sciencedirect.com
    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
    1
    1. scibot 02 Jun 2023
      RRID:AB_2885199

      DOI: 10.1016/j.cell.2023.05.005

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    sciencedirect.com/science/article/pii/S009286742300524X
  15. May 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome
    1
    1. scibot 18 May 2023
      RRID:AB_2885199

      DOI: 10.1016/j.isci.2023.106758

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    sciencedirect.com/science/article/pii/S2589004223008350
  17. Mar 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
    1
    1. scibot 28 Mar 2023
      RRID:AB_2885199

      DOI: 10.1016/j.immuni.2023.02.014

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    sciencedirect.com/science/article/pii/S1074761323000882
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease
    1
    1. scibot 23 Mar 2023
      RRID:AB_2885199

      DOI: 10.1186/s12974-023-02759-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10029189/
  20. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
    1
    1. scibot 17 Mar 2023
      RRID:AB_2885199

      DOI: 10.1016/j.celrep.2023.112265

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    pubmed.ncbi.nlm.nih.gov/36930645/
  21. Feb 2023
  22. www.sciencedirect.com www.sciencedirect.com
    CAR-T cells targeting HLA-G as potent therapeutic strategy for EGFR mutated and overexpressed oral cancer
    1
    1. scibot 25 Feb 2023
      RRID:AB_2885199

      DOI: 10.1016/j.isci.2023.106089

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    sciencedirect.com/science/article/pii/S2589004223001669
  23. Jan 2023
  24. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
    1
    1. scibot 26 Jan 2023
      AB_2885199

      DOI: 10.1126/scisignal.abh1083

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      Curator: @scibot

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    science.org/doi/10.1126/scisignal.abh1083
  25. Oct 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
    1
    1. scibot 26 Oct 2022
      RRID:AB_2885199

      DOI: 10.1016/j.celrep.2022.111532

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    sciencedirect.com/science/article/pii/S2211124722013882
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
    1
    1. scibot 12 Oct 2022
      AB_2885199

      DOI: 10.3389/fimmu.2022.912069

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550078/
  28. Jun 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
    1
    1. scibot 02 Jun 2022
      RRID:AB_2885199

      DOI: 10.1016/j.neuron.2022.05.009

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    sciencedirect.com/science/article/pii/S0896627322004500
  30. Dec 2021
  31. www.sciencedirect.com www.sciencedirect.com
    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
    1
    1. scibot 03 Dec 2021
      RRID:AB_2885199

      DOI: 10.1016/j.cell.2021.11.011

      Resource: (AdipoGen Cat# AG-20B-0014-C100, RRID:AB_2885199)

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    sciencedirect.com/science/article/pii/S009286742101326X
  32. Nov 2021
  33. www.sciencedirect.com www.sciencedirect.com
    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
    1
    1. scibot 09 Nov 2021
      RRID:AB_2885199

      DOI: 10.1016/j.immuni.2021.10.004

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    sciencedirect.com/science/article/pii/S1074761321004106
  34. Sep 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
    1
    1. scibot 22 Sep 2021
      RRID:AB_2885199

      DOI: 10.1016/j.celrep.2021.109720

      Resource: (AdipoGen Cat# AG-20B-0014-C100, RRID:AB_2885199)

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    sciencedirect.com/science/article/pii/S2211124721011694
  36. Jun 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
    1
    1. scibot 12 Jun 2021
      AG-20B-0014-C100

      DOI: 10.1016/j.immuni.2021.05.004

      Resource: (AdipoGen Cat# AG-20B-0014-C100, RRID:AB_2885199)

      Curator: @Naa003

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      RRID:AB_2885199 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1074761321002107