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  1. Last 7 days
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    Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway
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    sciencedirect.com/science/article/pii/S0006295226002959
  3. Feb 2026
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    The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation
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    sciencedirect.com/science/article/pii/S245194562600022X
  5. Jan 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clostridium scindens attenuates acute kidney injury by producing indole-3-acetic acid
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    pmc.ncbi.nlm.nih.gov/articles/PMC12816017/
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    Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models
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    dx.doi.org/10.1093/jleuko/qiaf157
  8. Aug 2025
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    Homocysitaconate controls inflammation through reshaping methionine metabolism and N-homocysteinylation
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    sciencedirect.com/science/article/pii/S1550413125003572
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    Nrf2/Nlrp3 Signaling in Aging BMSCs: Traf6 Intervention as a Novel Approach to Osteoporosis Treatment
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  11. Jul 2025
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    Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma
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    Colchicine inhibits vascular calcification by suppressing inflammasome activation through the enhancement of the Sirt2-PP2Ac signaling pathway
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    sciencedirect.com/science/article/pii/S0021925825022318
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    Nuclear Receptor ERRγ Protects Against Cardiac Ischemic Injury by Suppressing GBP5‐Mediated Myocardial Inflammation
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  15. Jun 2025
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  17. May 2025
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    Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways
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    Tong-Qiao-Huo-Xue Decoction mitigates post-stroke inflammatory response via suppression of the FIB-NLRP3 signaling pathway
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    link.springer.com/article/10.1007/s11011-025-01633-7
  20. Feb 2025
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    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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    sciencedirect.com/science/article/pii/S0925443925000821
  22. aacrjournals.org aacrjournals.org
    LRRC75A-AS1 drives the epithelial-mesenchymal transition in cervical cancer by binding IGF2BP1 and inhibiting SYVN1-mediated NLRP3 ubiquitination
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    aacrjournals.org/mcr/article/22/12/1075/750095/LRRC75A-AS1-Drives-the-Epithelial-Mesenchymal
  23. Jan 2025
  24. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Actions of dexmedetomidine in regulating NLRP3 in postoperative cognitive dysfunction in aged mice via the autophagy–lysosome pathway
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17378
  25. Dec 2024
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effect of NLRP3 inflammasome induced astrocyte phenotype alteration in morphine tolerance
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  27. Jul 2024
  28. link.springer.com link.springer.com
    Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation
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    link.springer.com/article/10.1007/s12035-024-04365-4
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  30. Jun 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152575/
  32. May 2024
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    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
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  35. Apr 2024
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  37. Mar 2024
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    Effects of the Glucocorticoid-Mediated Mitochondrial Translocation of Glucocorticoid Receptors on Oxidative Stress and Pyroptosis in BV-2 Microglia
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  39. Feb 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC6A14 promotes ulcerative colitis progression by facilitating NLRP3 inflammasome-mediated pyroptosis
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  41. Jan 2024
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    Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation
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  43. Dec 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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  45. Nov 2023
  46. www.tandfonline.com www.tandfonline.com
    Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia
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    tandfonline.com/doi/abs/10.1080/01902148.2023.2266236
  47. Sep 2023
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    GAS5-inhibited hepatocyte pyroptosis contributes to hepatic stellate cell inactivation via microRNA-684 and AHR
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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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  50. Aug 2023
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    Electroacupuncture attenuates myocardial ischemia-reperfusion injury by inhibiting microglial engulfment of dendritic spines
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    TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia
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    Artificial cells delivering itaconic acid induce anti-inflammatory memory-like macrophages to reverse acute liver failure and prevent reinjury
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    sciencedirect.com/science/article/pii/S2666379123002604
  54. Jun 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced Neural Stem Cells Suppressed Neuroinflammation by Inhibiting the Microglial Pyroptotic Pathway in Intracerebral Hemorrhage Rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285565/
  56. Feb 2023
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    Pectic polysaccharides derived from Hainan Rauwolfia ameliorates NLRP3-mediated colonic epithelial cell pyroptosis in ulcerative colitis
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    52.53.155.43/78ecb96917095d55db195a4b002f5ed1d04a619d/physiolgenomics.00081.2022-html.html
  58. Jan 2023
  59. journals.physiology.org journals.physiology.org
    Pectic polysaccharides derived from Hainan Rauwolfia ameliorate NLR family pyrin domain-containing 3-mediated colonic epithelial cell pyroptosis in ulcerative colitis
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    journals.physiology.org/doi/10.1152/physiolgenomics.00081.2022
  60. Dec 2022
  61. www.cmghjournal.org www.cmghjournal.org
    Klebsiella pneumoniae induces inflammatory bowel disease through caspase-11-mediated IL-18 in the gut epithelial cells
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    cmghjournal.org/article/S2352-345X(22)00238-7/abstract
  62. Sep 2022
  63. link.springer.com link.springer.com
    Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
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    link.springer.com/article/10.1007/s11064-022-03751-5
  64. Aug 2022
  65. journals.lww.com journals.lww.com
    Chronic spinal cord compression associated with... : Neural Regeneration Research
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    β2-Microglobulin exacerbates neuroinflammation, brain... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/03000/_2_Microglobulin_exacerbates_neuroinflammation,.38.aspx
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9396479/
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15678
  69. Apr 2022
  70. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Alpha1-adrenoceptors activate NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation
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    physoc.onlinelibrary.wiley.com/doi/10.1113/EP090243
  71. journals.lww.com journals.lww.com
    Obstructive sleep apnea aggravates neuroinflammation and... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2022/11000/Obstructive_sleep_apnea_aggravates.43.aspx