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Combination of racotumomab immunotherapy with programmed death-1 blockade in a preclinical model of non-small cell lung cancer

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1. scibot 25 Oct 2025
  
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  DOI: 10.21037/tlcr-2025-230
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12541832/
Oct 2025
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Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102371
  
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sciencedirect.com/science/article/pii/S2666379125004446
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Phocaeicola vulgatus induces immunotherapy resistance in hepatocellular carcinoma via reducing indoleacetic acid production

1
1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102370
  
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sciencedirect.com/science/article/pii/S2666379125004434
Sep 2025
www.biorxiv.org www.biorxiv.org

Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis

1
1. scibot 10 Sep 2025
  
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  DOI: 10.1101/2025.08.30.673054
  
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biorxiv.org/content/10.1101/2025.08.30.673054v1
elifesciences.org elifesciences.org

NOLC1 suppresses immunochemotherapy by inhibiting p53-mediated ferroptosis in gastric cancer

1
1. scibot 04 Sep 2025
  
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  DOI: 10.7554/eLife.103904
  
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elifesciences.org/articles/103904
Aug 2025
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Inhibiting KRAS with CD47 and immune checkpoint overcomes intrinsic resistance to combined KRAS and immune checkpoint inhibitor therapy

1
1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102317
  
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sciencedirect.com/science/article/pii/S2666379125003908
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Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment

1
1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102312
  
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sciencedirect.com/science/article/pii/S2666379125003854
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Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

1
1. scibot 26 Aug 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.xcrm.2025.102307
  
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sciencedirect.com/science/article/pii/S2666379125003805
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High-dose ascorbic acid selectively induces pyroptosis in LKB1-deficient lung cancer and sensitizes immunotherapy

1
1. scibot 19 Aug 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.xcrm.2025.102291
  
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sciencedirect.com/science/article/pii/S2666379125003647
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USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment

1
1. scibot 05 Aug 2025
  
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  AB_2890649
  
  DOI: 10.1158/2326-6066.CIR-24-1194
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12314529/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PLT012, a humanized CD36-blocking antibody, is effective for unleashing anti-tumor immunity against liver cancer and liver metastasis

1
1. scibot 30 Jul 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1158/2159-8290.CD-24-1409
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617665/
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Interferon-driven CAF reprogramming augments immunogenic response to neoadjuvant radiotherapy in colorectal cancer

1
1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102251
  
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sciencedirect.com/science/article/pii/S2666379125003246
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Inhibition of KAT6A Enhances Immunotherapy Efficacy in Colorectal Cancer by Activating Interferon Response

1
1. scibot 23 Jul 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.canlet.2025.217946
  
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sciencedirect.com/science/article/pii/S0304383525005154
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Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

1
1. scibot 16 Jul 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.xcrm.2025.102239
  
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sciencedirect.com/science/article/pii/S266637912500312X
Jun 2025
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A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis

1
1. scibot 28 Jun 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.ccell.2025.06.006
  
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sciencedirect.com/science/article/pii/S1535610825002569
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Cisplatin and temozolomide combinatorial treatment triggers hypermutability and immune surveillance in experimental cancer models

1
1. scibot 13 Jun 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.ccell.2025.05.014
  
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sciencedirect.com/science/article/pii/S1535610825002235
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225010132-main-html.html

1
1. scibot 29 May 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.isci.2025.112752
  
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52.53.155.43/9003c45fae7689dd9660ec2260acff69b9d30974/1-s2.0-S2589004225010132-main-html.html
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 21 May 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1158/2159-8290.cd-24-1409
  
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52.53.155.43/449eeec941982dcbbbd18cfe95d7f2b03d57e236/PDF-html.html
Apr 2025
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Carvedilol sensitizes chemotherapy by targeting STING to boost anti-tumor immunity

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1. scibot 19 Apr 2025
  
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  AB_2890649
  
  DOI: 10.1016/j.celrep.2025.115572
  
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sciencedirect.com/science/article/pii/S2211124725003432
52.53.155.43 52.53.155.43

1-s2.0-S0016508525005426-main-html.html

1
1. scibot 05 Apr 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1053/j.gastro.2025.03.019
  
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52.53.155.43/417f7e11cf34a4a05dabce5f916b0d6ed71a75c4/1-s2.0-S0016508525005426-main-html.html
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Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.ccell.2025.03.015
  
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sciencedirect.com/science/article/pii/S1535610825001163
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combination of Bremachlorin PDT and Immune Checkpoint Inhibitor Anti–PD-1 Shows Response in Murine Immunological T-cell–High and T-cell–Low PDAC Models

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1. scibot 04 Apr 2025
  
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  DOI: 10.1158/1535-7163.MCT-23-0733
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11962392/
Mar 2025
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PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy

1
1. scibot 14 Mar 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.ccell.2025.02.024
  
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sciencedirect.com/science/article/pii/S1535610825000765
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PRMT3 drives PD-L1-mediated immune escape through activating PDHK1-regulated glycolysis in hepatocellular carcinoma

1
1. scibot 11 Mar 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1038/s41419-025-07482-7
  
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link.springer.com/article/10.1038/s41419-025-07482-7
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Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model

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1. scibot 04 Mar 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1038/s41598-025-91872-6
  
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link.springer.com/article/10.1038/s41598-025-91872-6
Jan 2025
www.nature.com www.nature.com

Systemic IFN-I combined with topical TLR7/8 agonists promotes distant tumor suppression by c-Jun-dependent IL-12 expression in dendritic cells

1
1. scibot 24 Jan 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1038/s43018-024-00889-9
  
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nature.com/articles/s43018-024-00889-9
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Signatures of H3K4me3 modification predict cancer immunotherapy response and identify a new immune checkpoint-SLAMF9

1
1. scibot 18 Jan 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1186/s12931-024-03093-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11734478/
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Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice

1
1. scibot 15 Jan 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1186/s13046-024-03238-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11705946/
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

1
1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101887
  
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Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing

1
1. scibot 14 Jan 2025
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.neuron.2024.12.012
  
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sciencedirect.com/science/article/pii/S0896627324009115
Dec 2024
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Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101877
  
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sciencedirect.com/science/article/pii/S2666379124006487
Nov 2024
52.53.155.43 52.53.155.43

strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

1
1. scibot 14 Nov 2024
  
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  AB_2890649
  
  DOI: 10.1038/s44321-024-00166-3
  
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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
www.embopress.org www.embopress.org

JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

2
1. scibot 14 Nov 2024
  
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  RRID:AB_2890649
  
  DOI: 10.1038/s44321-024-00166-3
  
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  RRID:AB_2890649
  
  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
Sep 2024
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CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway

1
1. scibot 26 Sep 2024
  
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  AB_2890649
  
  DOI: 10.1016/j.xgen.2024.100659
  
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Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment

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TLR3 activation enhances abscopal effect of radiotherapy in HCC by promoting tumor ferroptosis | EMBO Molecular Medicine

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  DOI: 10.1038/s44321-024-00068-4
  
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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE2 production

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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity

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Next-generation anti-PD-L1/IL-15 immunocytokine elicits superior antitumor immunity in cold tumors with minimal toxicity

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TLR3 activation enhances abscopal effect of radiotherapy in HCC by promoting tumor ferroptosis

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Apr 2024
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QDPR deficiency drives immune suppression in pancreatic cancer

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Mar 2024
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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

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A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer

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Feb 2024
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Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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Jan 2024
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Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

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A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity

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Rebalancing TGF-β/PGE2 breaks RT-induced immunosuppressive barriers by enhancing tumor-infiltrated dendritic cell homing

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  DOI: 10.7150/ijbs.87867
  
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Dec 2023
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Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression

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Preventive Treatment with PD-1 Antibody Increases Tissue-Resident Memory T Cells Infiltration and Delays Esophageal Carcinogenesis

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  DOI: 10.1158/1940-6207.CAPR-23-0196
  
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capr-23-0196-html.html

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Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell

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SSRN-id4540281-html.html

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Sep 2023
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Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

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Aug 2023
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can-23-1252-html.html

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May 2023
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Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling

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Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma

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Apr 2023
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Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion

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  DOI: 10.1101/2023.03.28.534575
  
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Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas

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  DOI: 10.1101/2023.02.13.528351
  
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Feb 2023
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Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer

1
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Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS

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Jan 2023
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Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma

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Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma

1
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Dec 2022
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EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer

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Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis

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  DOI: 10.1016/j.isci.2022.105511
  
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Nov 2022
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CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition

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  DOI: 10.1016/j.ccell.2022.10.015
  
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Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer

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  DOI: 10.1016/j.celrep.2022.111596
  
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Oct 2022
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PARP-inhibition reprograms macrophages toward an anti-tumor phenotype

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1. scibot 13 Oct 2022
  
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  RRID:AB_2890649
  
  DOI: 10.1016/j.celrep.2022.111462
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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sciencedirect.com/science/article/pii/S2211124722013079
www.sciencedirect.com www.sciencedirect.com

Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas

1
1. scibot 07 Oct 2022
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1016/j.molcel.2022.09.007
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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sciencedirect.com/science/article/pii/S1097276522008966
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis

1
1. scibot 12 Aug 2022
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1016/j.chom.2022.07.003
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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sciencedirect.com/science/article/pii/S1931312822003493
Jul 2022
link.springer.com link.springer.com

The immunometabolite S-2-hydroxyglutarate exacerbates perioperative ischemic brain injury and cognitive dysfunction by enhancing CD8+ T lymphocyte-mediated neurotoxicity

1
1. scibot 09 Jul 2022
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1186/s12974-022-02537-4
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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link.springer.com/article/10.1186/s12974-022-02537-4
Dec 2021
www.sciencedirect.com www.sciencedirect.com

AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells

1
1. scibot 21 Dec 2021
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1016/j.isci.2021.103570
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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sciencedirect.com/science/article/pii/S2589004221015406
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell

1
1. scibot 18 Sep 2021
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1136/jitc-2021-003100
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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ncbi.nlm.nih.gov/pmc/articles/PMC8407215/
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Effects of exercise and anti-PD-1 on the tumour microenvironment

1
1. scibot 08 Sep 2021
  
  in Public
  
  ab217344
  
  DOI: 10.1016/j.imlet.2021.08.005
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2890649
  
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  RRIDCUR:Missing RRID:AB_2890649
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sciencedirect.com/science/article/abs/pii/S0165247821001401
Aug 2021
www.sciencedirect.com www.sciencedirect.com

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

1
1. scibot 06 Aug 2021
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1016/j.ccell.2021.07.007
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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sciencedirect.com/science/article/pii/S1535610821003846
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection

1
1. scibot 18 Jun 2021
  
  in Public
  
  RRID:AB_2890649
  
  DOI: 10.1016/j.isci.2021.102555
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2890649
  
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  RRID:AB_2890649
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ncbi.nlm.nih.gov/pmc/articles/PMC8188550/
www.sciencedirect.com www.sciencedirect.com

Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome

1
1. scibot 02 Jun 2021
  
  in Public
  
  RRID:B_2890649
  
  DOI: 10.1016/j.celrep.2021.109201
  
  Resource: (Abcam Cat# ab217344, RRID:AB_2890649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2890649
  
  Curator comments: Recombinant Anti-CD8 alpha antibody [EPR21769] Abcam Cat# ab217344
  
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  RRIDCUR:Unresolved RRIDCUR:Incorrect RRID:AB_2890649
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sciencedirect.com/science/article/pii/S2211124721005507

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