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Impaired macroautophagy in oligodendrocyte precursor cells suppresses neuronal plasticity via a senescence-associated signaling

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1. scibot 27 Sep 2025
  
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  DOI: 10.1126/sciadv.adq7665
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12459396/
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Nucleolar stress facilitates islet β cell senescence via hijacking the DNA damage response pathways

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113508
  
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sciencedirect.com/science/article/pii/S2589004225017699
Aug 2025
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An age-related decrease in leptin contributes to CD8+ T cell aging in the tumor microenvironment

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102310
  
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sciencedirect.com/science/article/pii/S2666379125003830
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Nrf2/Nlrp3 Signaling in Aging BMSCs: Traf6 Intervention as a Novel Approach to Osteoporosis Treatment

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1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.redox.2025.103804
  
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sciencedirect.com/science/article/pii/S2213231725003179
Jul 2025
www.cell.com www.cell.com

Divergent sex-specific effects on a ketogenic diet: Male, but not female, mice exhibit oxidative stress and cellular senescence

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116026
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00797-1
May 2025
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Single-nucleus profiling of mouse inner ear aging uncovers cell type heterogeneity and hair cell subtype-specific age-related signatures

1
1. scibot 29 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115781
  
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sciencedirect.com/science/article/pii/S2211124725005522
Apr 2025
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

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1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.immuni.2025.03.005
  
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sciencedirect.com/science/article/pii/S1074761325001244
Feb 2025
aacrjournals.org aacrjournals.org

Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger Bone Destruction in Breast Cancer Metastasis

1
1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-0857
  
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aacrjournals.org/cancerres/article/84/23/3936/750181/Single-Cell-Transcriptomic-Analysis-Identifies
Jan 2025
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Cdk6’s functions are critically regulated by its unique C-terminus

1
1. scibot 30 Jan 2025
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.isci.2024.111697
  
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sciencedirect.com/science/article/pii/S2589004224029249
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb

1
1. scibot 21 Nov 2024
  
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  RRID:AB_2891084
  
  DOI: 10.1038/s44318-024-00246-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
Sep 2024
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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

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1. scibot 25 Sep 2024
  
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  AB_2891084
  
  DOI: 10.1016/j.ccell.2024.08.018
  
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sciencedirect.com/science/article/pii/S1535610824003179
Aug 2024
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Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function

1
1. scibot 19 Aug 2024
  
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  AB_2891084
  
  DOI: 10.1016/j.cmet.2024.07.006
  
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sciencedirect.com/science/article/pii/S1550413124002778
Jul 2024
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TERT activation targets DNA methylation and multiple aging hallmarks

1
1. scibot 24 Jul 2024
  
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  AB_2891084
  
  DOI: 10.1016/j.cell.2024.05.048
  
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sciencedirect.com/science/article/pii/S0092867424005920
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Autophagy regulates age-related delayed jawbone regeneration and decreased osteoblast osteogenesis by degrading FABP3

1
1. scibot 23 Jul 2024
  
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  RRID:AB_2891084
  
  DOI: 10.1096/fj.202400549RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400549RR
Jan 2024
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Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging

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1. scibot 23 Jan 2024
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.immuni.2024.01.001
  
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sciencedirect.com/science/article/pii/S1074761324000268
Nov 2023
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Mechanical overloading leads to chondrocyte degeneration and senescence via Zmpste24 mediated nuclear membrane instability

2
1. scibot 04 Nov 2023
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.isci.2023.108119
  
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2. scibot 04 Nov 2023
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.isci.2023.108119
  
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sciencedirect.com/science/article/pii/S258900422302196X
Oct 2023
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A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells

1
1. scibot 13 Oct 2023
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.molcel.2023.09.006
  
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sciencedirect.com/science/article/pii/S1097276523007037
Jun 2023
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Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response

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1. scibot 27 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.107090
  
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sciencedirect.com/science/article/pii/S2589004223011677
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Characterizing microglial senescence: Tau as a key player

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1. scibot 08 Jun 2023
  
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  RRID:AB_2891084
  
  DOI: 10.1111/jnc.15866
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15866
May 2023
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Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin

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1. scibot 11 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112472
  
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sciencedirect.com/science/article/pii/S2211124723004837
Apr 2023
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Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.04.005
  
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sciencedirect.com/science/article/pii/S1534580723001582
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Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.cmet.2023.03.005
  
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sciencedirect.com/science/article/pii/S1550413123000839
Mar 2023
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Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.02.004
  
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sciencedirect.com/science/article/pii/S1535610823000326
Jan 2023
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Immunoediting instructs tumor metabolic reprogramming to support immune evasion

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1. scibot 04 Jan 2023
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.cmet.2022.12.003
  
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sciencedirect.com/science/article/pii/S155041312200540X
Nov 2021
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Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity

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1. scibot 23 Nov 2021
  
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  RRID:AB_2891084
  
  DOI: 10.1016/j.cmet.2021.11.002
  
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sciencedirect.com/science/article/pii/S1550413121005301
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Modulation of fracture healing by the transient accumulation of senescent cells

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1. scibot 23 Oct 2021
  
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  RRID:AB_2891084
  
  DOI: 10.7554/eLife.69958
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8526061/