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KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.08.003
  
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sciencedirect.com/science/article/pii/S1097276525006537
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Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.chembiol.2025.07.006
  
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sciencedirect.com/science/article/pii/S2451945625002296
Aug 2025
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Adiphenine Alleviates Impulsive-Like Behaviors in Aged Mice by Inhibiting Nicotinic Acetylcholine Receptors

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1. scibot 14 Aug 2025
  
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  DOI: 10.1111/jnc.70190
  
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52.53.155.43 52.53.155.43

2025.08.06.668899v1.full-html.html

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  DOI: 10.1101/2025.08.06.668899
  
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52.53.155.43/54427366624e4701e0e08ab46e106362d151106f/2025.08.06.668899v1.full-html.html
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
Jul 2025
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Pantothenate protects against obesity via brown adipose tissue activation

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1. scibot 22 Jul 2025
  
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  DOI: 10.1152/ajpendo.00293.2021
  
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  DOI: 10.1152/ajpendo.00293.2021
  
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52.53.155.43/7317937cd95e74d813ceb6e8f27034de131d4071/zhou-et-al-2022-pantothenate-protects-against-obesity-via-brown-adipose-tissue-activation-html.html
Jun 2025
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Identifying the target, mechanism, and agonist of α-ketoglutaric acid in delaying mesenchymal stem cell senescence

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115917
  
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sciencedirect.com/science/article/pii/S2211124725006886
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Nociceptor-derived CGRP enhances dermal type I conventional dendritic cell function to drive autoreactive CD8+ T cell responses in vitiligo

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.018
  
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sciencedirect.com/science/article/pii/S1074761325002390
May 2025
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KDELR3 is transcriptionally activated by FOXM1 and accelerates lung adenocarcinoma growth and metastasis via inhibiting endoplasmic reticulum stress-induced cell apoptosis

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1. scibot 29 May 2025
  
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  DOI: 10.1007/s13577-025-01238-3
  
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link.springer.com/article/10.1007/s13577-025-01238-3
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Activation of an antifungal pathway in Yersinia pseudotuberculosis by chitin-receptor-mediated fungal recognition

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  DOI: 10.1016/j.cub.2025.04.072
  
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sciencedirect.com/science/article/pii/S096098222500569X
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Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102090
  
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Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.012
  
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sciencedirect.com/science/article/pii/S0092867425004143
Apr 2025
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1-s2.0-S2589004225007199-main-html.html

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1. scibot 19 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112458
  
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52.53.155.43/dcc1b4035af7cd13ce5b049834e2847586d98517/1-s2.0-S2589004225007199-main-html.html
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O-GlcNAcylation-mediated endothelial metabolic memory contributes to cardiac damage via small extracellular vesicles

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.cmet.2025.03.006
  
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sciencedirect.com/science/article/pii/S1550413125001093
Feb 2025
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1-s2.0-S2589004225003700-main-html.html

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.112110
  
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Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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1. scibot 26 Feb 2025
  
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  DOI: 10.1084/jem.20231486
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
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Nrg4 Secreted by Brown Adipose Tissue Suppresses Ferroptosis of Sepsis-Induced Liver Injury

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1. scibot 20 Feb 2025
  
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  DOI: 10.1007/s10753-024-02230-z
  
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The concomitant tumor suspension cells derived from skbr-3 exhibit circulating tumor cell features

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1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.tice.2025.102777
  
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sciencedirect.com/science/article/pii/S0040816625000576
Dec 2024
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Temperature perception by ER UPR promotes preventive innate immunity and longevity

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  DOI: 10.1016/j.celrep.2024.115071
  
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Nov 2024
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Gut commensal Agathobacter rectalis alleviates microglia-mediated neuroinflammation against pathogenesis of Alzheimer’s disease

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1. scibot 17 Nov 2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11532950/
Oct 2024
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Genetic deletion of the apoptosis associated speck like protein containing a card in LysM+ macrophages attenuates spinal cord injury by regulating M1/M2 polarization through ASC-dependent inflammasome signaling axis

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sciencedirect.com/science/article/pii/S001448862400308X
Sep 2024
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ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancer

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1. scibot 15 Sep 2024
  
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  DOI: 10.1038/s41388-024-03154-6
  
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nature.com/articles/s41388-024-03154-6
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Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway

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1. scibot 12 Sep 2024
  
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Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI

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  DOI: 10.1016/j.celrep.2024.114670
  
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Aug 2024
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BBOX1 mediates metabolic reprogramming driven by hypoxia and participates in the malignant progress of high-grade serous ovarian cancer

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.bbamcr.2024.119830
  
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Regulation of Glycolysis-Derived L-lactate Production in Astrocytes Rescues the Memory Deficits and Aβ Burden in Early Alzheimer’s Disease Models

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  DOI: 10.1016/j.phrs.2024.107357
  
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Protocol for evaluating S-acylated protein membrane affinity using protein-lipid conjugates

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.xpro.2024.103182
  
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Mdivi-1 alleviates ferroptosis induced by hypoxia combined with propofol in HT22 cells by inhibiting excessive mitophagy

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  DOI: 10.1007/s11033-024-09812-y
  
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link.springer.com/article/10.1007/s11033-024-09812-y
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Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.385308
  
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journals.lww.com/nrronline/fulltext/2026/04000/the_cullin3_ring_e3_ubiquitin_ligase_complex_and.44.aspx
Jul 2024
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Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway

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Mitochondrial transfer between BMSCs and Müller promotes mitochondrial fusion and suppresses gliosis in degenerative retina

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1. scibot 24 Jul 2024
  
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Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114402
  
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sciencedirect.com/science/article/pii/S2211124724007307
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Autophagy regulates age-related delayed jawbone regeneration and decreased osteoblast osteogenesis by degrading FABP3

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1. scibot 23 Jul 2024
  
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  DOI: 10.1096/fj.202400549RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400549RR
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Protocol for evaluating the effects of large gradient high magnetic fields on osteocyte function

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ASGR1 Is a Promising Target for Lipid Reduction in Pigs with PON2 As Its Inhibitor

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Network Pharmacology and Bioinformatics Analysis to Identify the Molecular Targets and its Biological Mechanisms of Sciadopitysin against Glioblastoma

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Resident Vascular Sca1+ Progenitors Differentiate into Endothelial Cells in Vascular Remodeling via miR-145-5p/ERG Signaling Pathway

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Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice

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Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells

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A novel role of microtubule affinity-regulating kinases in neuropathic pain

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BPS Publications

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Wybutosine hypomodification of tRNAphe activates HERVK and impairs neuronal differentiation

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Wolbachia symbionts control sex in a parasitoid wasp using a horizontally acquired gene

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5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation

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Vascular endothelial cells derived exosomes synergize with curcumin to prevent osteoporosis development

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TSPYL2 induces renal ischemia-reperfusion injury through SREBP-2/ACMSD signaling

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IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling

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Hyperthermia improves gemcitabine sensitivity of pancreatic cancer cells by suppressing the EFNA4/β-catenin axis and activating dCK

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Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway

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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

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EPC1/2 regulate hematopoietic stem and progenitor cell proliferation by modulating H3 acetylation and DLST

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Structure-based design of non-hypertrophic apelin receptor modulator

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Melatonin improves synapse development by PI3K/Akt signaling in a mouse model of autism spectrum disorder

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Transcription factor ZNF263 enhances EGFR-targeted therapeutic response and reduces residual disease in lung adenocarcinoma

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Inhibition of CD44 suppresses the formation of fibrotic scar after spinal cord injury via the JAK2/STAT3 signaling pathway

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Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis

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HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling

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Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival

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Natural variants of molybdate transporters contribute to yield traits of soybean by affecting auxin synthesis

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Hypoxia-sensitive cells trigger NK cell activation via the KLF4-ASH1L-ICAM-1 axis, contributing to impairment in the rat epididymis

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BPS Publications

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S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy

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dgad562-html.html

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PPP1R3A inhibits Osteogenesis and Negatively Regulates Intracellular Calcium Levels in Calcific Tendinopathy

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Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions

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Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1

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Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway

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Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury

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Schwann cell-derived amphiregulin enhances nerve regeneration via supporting the proliferation and migration of Schwann cells and the elongation of axons

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Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice

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Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine

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miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke

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Protocol for IPO11 deletion and re-expression in H460 lung cancer cells using CRISPR-Cas9 and plasmid transfection

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CKB regulates BCAR1 phosphorylation to facilitate DNA damage repair

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Sphingosine 1-phosphate receptor 1 regulates bloodbrain... : Neural Regeneration Research

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Poly(ADP-ribose) polymerase family member 14 promotes... : Neural Regeneration Research

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Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila

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Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

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Inhibiting 5-hydroxytryptamine receptor 3 alleviates... : Neural Regeneration Research

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KDM4A, involved in the inflammatory and oxidative stress caused by traumatic brain injury-hemorrhagic shock, partly through the regulation of the microglia M1 polarization

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Mechanistic insights into CDCP1 clustering on non-small-cell lung cancer membranes revealed by super-resolution fluorescent imaging

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Long noncoding RNA H19 regulates degeneration and... : Neural Regeneration Research

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Macrophage migration inhibitory factor facilitates... : Neural Regeneration Research

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Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules

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Multi-omics profiling visualizes dynamics of cardiac development and functions

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Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury

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ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis

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Methylmalonic acid levels in serum, exosomes, and urine and its association with cblC type methylmalonic acidemia-induced cognitive impairment

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Spatial heterogeneity of infiltrating T cells in high-grade serous ovarian cancer revealed by multi-omics analysis

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CHD2 maintains spermatogonial self-renewal by promoting chromatin accessibility and mRNA stability

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Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios

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Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation

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Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice

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Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis

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Double-target neural circuit-magnetic stimulation improves... : Neural Regeneration Research

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m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress

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Adiponectin ameliorates hypertrophic scar by inhibiting YAP transcription through SIRT1-mediated deacetylation of C/EBPβ and histone H3

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Poly-L-ornithine blocks the inhibitory effects of... : Neural Regeneration Research

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RPRM negatively regulates ATM levels through its nuclear translocation upon irradiation mediated by CDK4/6 and IPO11

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Hypoxia upregulates the expression of lncRNA H19 in non-small cell lung cancer cells and induces drug resistance

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Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord

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Chronic spinal cord compression associated with... : Neural Regeneration Research

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Neuroprotective effects of neural stem cells pretreated... : Neural Regeneration Research

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Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi

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Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response

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ajpendo.00293.2021-html.html

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A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism

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BPS Publications

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Delicate regulation of IL-1β-mediated inflammation by cyclophilin A

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High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase knockout rats

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The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus

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Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains

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Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC1

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A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP

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