Hypothesis

19 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

1
1. scibot 10 Feb 2026
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/2159-8290.CD-25-0525
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12877752/
May 2025
www.sciencedirect.com www.sciencedirect.com

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.ccell.2025.04.014
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825001734
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Dependence on Mdm2 for Mdm4 inhibition of p53 activity

1
1. scibot 13 Mar 2025
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.canlet.2025.217622
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0304383525001867
May 2024
www.sciencedirect.com www.sciencedirect.com

Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor

1
1. scibot 07 May 2024
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.stem.2024.04.011
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590924001383
Feb 2024
aacrjournals.org aacrjournals.org

Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models

1
1. scibot 27 Feb 2024
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/2767-9764.CRC-23-0308
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
www.sciencedirect.com www.sciencedirect.com

PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

1
1. scibot 06 Feb 2024
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.cmet.2024.01.006
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413124000056
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants

1
1. scibot 18 Jan 2024
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/0008-5472.CAN-22-3464
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10524763/
aacrjournals.org aacrjournals.org

Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models

1
1. scibot 10 Jan 2024
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/2767-9764.CRC-23-0308
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Temporary Knockdown of p53 During Focal Limb Irradiation Increases the Development of Sarcomas

1
1. scibot 07 Dec 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/2767-9764.CRC-23-0104
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10697056/
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.7554/eLife.84710
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10519710/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Thymine DNA glycosylase regulates cell-cycle-driven p53 transcriptional control in pluripotent cells

1
1. scibot 28 Jul 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.molcel.2023.07.003
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/abs/pii/S1097276523005178
www.sciencedirect.com www.sciencedirect.com

Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism

1
1. scibot 21 Jul 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.cmet.2023.06.014
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/abs/pii/S1550413123002243
Jun 2023
52.53.155.43 52.53.155.43

can-22-3464-html.html

1
1. scibot 30 Jun 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/0008-5472.can-22-3464
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

52.53.155.43/8f4ba7cf674bbb2f5b6878f674808aab8499538e/can-22-3464-html.html
May 2023
www.sciencedirect.com www.sciencedirect.com

Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin

1
1. scibot 11 May 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.celrep.2023.112472
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723004837
Apr 2023
www.nature.com www.nature.com

Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy

1
1. scibot 11 Apr 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1038/s41467-023-37617-3
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

nature.com/articles/s41467-023-37617-3
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Injury primes mutation-bearing astrocytes for dedifferentiation in later life

1
1. scibot 25 Feb 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.cub.2023.02.013
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0960982223001525
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity

1
1. scibot 10 Feb 2023
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1158/2159-8290.CD-22-0528
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Metabolic regulation by p53 prevents R-loop-associated genomic instability

1
1. scibot 03 Nov 2022
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.celrep.2022.111568
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722014292
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis

1
1. scibot 20 Oct 2022
  
  in Public
  
  RRID:AB_2895247
  
  DOI: 10.1016/j.celrep.2022.111503
  
  Resource: (Leica Biosystems Cat# NCL-L-p53-CM5p, RRID:AB_2895247)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2895247
  
  What is this?
  
  RRID:AB_2895247
Visit annotations in context

Tags

RRID:AB_2895247

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722013535