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Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

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1. scibot 17 Oct 2025
  
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  DOI: 10.1158/0008-5472.CAN-25-1615
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12500318/
Aug 2025
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Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.07.006
  
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sciencedirect.com/science/article/pii/S1097276525006070
Jul 2025
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CF10/LV overcomes acquired resistance to 5-FU/LV in colorectal cancer cells through downregulation of the c-Myc/ABCB5 axis

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1. scibot 31 Jul 2025
  
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  DOI: 10.20517/cdr.2025.76
  
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oaepublish.com/articles/cdr.2025.76
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Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models

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1. scibot 22 Jul 2025
  
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  DOI: 10.3390/cancers17142342
  
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mdpi.com/2072-6694/17/14/2342
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BLIMP1 controls GC B cell expansion and exit through regulating cell cycle progression and key transcription factors BCL6 and IRF4

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115977
  
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sciencedirect.com/science/article/pii/S221112472500748X
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Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells

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1. scibot 01 Jul 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0058
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12202856/
Jun 2025
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PDF-html.html

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1. scibot 12 Jun 2025
  
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  DOI: 10.1158/2767-9764.crc-25-0058
  
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52.53.155.43/6f95ee3860ed32eb2fc3447b03e264cd8239544f/PDF-html.html
Apr 2025
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Co-targeting BMI1 and MYC to eliminate cancer stem cells in squamous cell carcinoma

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1. scibot 18 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147845/
Dec 2024
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Adipocyte-derived ferroptotic signaling mitigates obesity

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.cmet.2024.11.010
  
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cell.com/cell-metabolism/abstract/S1550-4131(24)00456-X
Nov 2024
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can-24-1817-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1158/0008-5472.can-24-1817
  
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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Jul 2024
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IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

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1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.05.026
  
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sciencedirect.com/science/article/pii/S1535610824002174
Jun 2024
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De novo and salvage purine synthesis pathways across tissues and tumors

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1. scibot 04 Jun 2024
  
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  Cell Signaling TechnologyCat# 18583S
  
  DOI: 10.1016/j.cell.2024.05.011
  
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  RRID:AB_2895543 DOI:10.1016/j.cell.2024.05.011
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sciencedirect.com/science/article/pii/S0092867424005208
May 2024
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eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer

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1. scibot 24 May 2024
  
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  RRID:AB_2895543
  
  DOI: 10.1126/scisignal.adh4475
  
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science.org/doi/10.1126/scisignal.adh4475
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Structural transitions enable interleukin-18 maturation and signaling

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.015
  
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sciencedirect.com/science/article/pii/S1074761324002206
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Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma

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1. scibot 02 May 2024
  
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  DOI: 10.1158/1078-0432.CCR-22-2854
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11060649/
Mar 2024
52.53.155.43 52.53.155.43

Targeting LTA4H facilitates the reshaping of the immune microenvironment mediated by CCL5 and sensitizes ovarian cancer to Cisplatin

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1. scibot 05 Mar 2024
  
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  DOI: 10.1007/s11427-023-2444-5
  
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52.53.155.43/87ec0518c5224f0fd07557d79aa684b0e2f086c0/s11427-023-2444-5 (1)-html.html
Jan 2024
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Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.cmet.2023.12.016
  
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sciencedirect.com/science/article/pii/S1550413123004679
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miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.

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1. scibot 18 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108650
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
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Ipsilateral immunization after a prior SARS-CoV-2 mRNA vaccination elicits superior B cell responses compared to contralateral immunization

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1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.celrep.2023.113665
  
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sciencedirect.com/science/article/pii/S2211124723016765
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Mechanism of GW117 antidepressant action: melatonin receptor-mediated regulation of sleep rhythm

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1. scibot 06 Jan 2024
  
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  DOI: 10.1016/j.ejphar.2023.176299
  
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sciencedirect.com/science/article/pii/S0014299923008130
Nov 2023
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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.xcrm.2023.101286
  
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sciencedirect.com/science/article/pii/S2666379123004809
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CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions

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1. scibot 02 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113306
  
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sciencedirect.com/science/article/pii/S2211124723013189
Oct 2023
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Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113211
  
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sciencedirect.com/science/article/pii/S2211124723012238
Sep 2023
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C-Myc-induced hypersialylation of small cell lung cancer facilitates pro-tumoral phenotypes of macrophages

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1. scibot 22 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107771
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10507237/
Aug 2023
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Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112979
  
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2. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112979
  
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52.53.155.43/491f3628ae56ca418965e7c0fc6856d1761b345d/PIIS2211124723009907-html.html
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SSRN-id4513724-html.html

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1. scibot 10 Aug 2023
  
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  DOI: 10.2139/ssrn.4513724
  
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52.53.155.43/5f78fb6f419d1fcb5e4cfbd3ef5a02650af33ba6/SSRN-id4513724-html.html
May 2023
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Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response

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1. scibot 24 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112557
  
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sciencedirect.com/science/article/pii/S2211124723005685
Apr 2023
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ZFP36-mediated mRNA decay regulates metabolism

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112411
  
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sciencedirect.com/science/article/pii/S2211124723004229
Dec 2022
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The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC

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1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111759
  
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sciencedirect.com/science/article/pii/S2211124722016424
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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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1. scibot 02 Dec 2022
  
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  DOI: 10.1016/j.ccell.2022.11.005
  
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sciencedirect.com/science/article/pii/S1535610822005529
Nov 2022
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MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors

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1. scibot 23 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111704
  
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sciencedirect.com/science/article/pii/S2211124722015789
Oct 2022
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Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas

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1. scibot 22 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.024
  
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sciencedirect.com/science/article/pii/S1097276522009340
Aug 2022
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Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα

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1. scibot 25 Aug 2022
  
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  DOI: 10.1016/j.cmet.2022.08.002
  
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sciencedirect.com/science/article/pii/S155041312200345X