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Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells

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1. scibot 03 Sep 2025
  
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  DOI: 10.7554/eLife.99344
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12387754/
Aug 2025
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Reconstruction of endocrine subtype-complete human pluripotent stem cell-derived islets with capacity for hypoglycemia protection in vivo

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1. scibot 09 Aug 2025
  
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  DOI: 10.1016/j.stem.2025.07.006
  
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sciencedirect.com/science/article/pii/S1934590925002632
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BPS Publications

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1. scibot 06 Aug 2025
  
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  DOI: 10.1111/bph.70139
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70139
Jul 2025
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Epigenome profiling identifies H3K27me3 regulation of extracellular matrix composition in human corticogenesis

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.neuron.2025.06.016
  
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sciencedirect.com/science/article/pii/S089662732500474X
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Protocol for immunostaining of non-adherent cells and cellular structures using centrifugal filter devices

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.xpro.2025.103934
  
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sciencedirect.com/science/article/pii/S2666166725003405
May 2025
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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.006
  
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sciencedirect.com/science/article/pii/S1074761325001694
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Influenza A virus dissemination and infection leads to tissue resident cell injury and dysfunction in viral sepsis

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.ebiom.2025.105738
  
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sciencedirect.com/science/article/pii/S2352396425001823
Feb 2025
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FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma

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1. scibot 28 Feb 2025
  
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  DOI: 10.1016/j.ccell.2025.02.001
  
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sciencedirect.com/science/article/pii/S1535610825000534
Jan 2025
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Cyclin-dependent kinase inhibitor p18 regulates lineage transitions of excitatory neurons, astrocytes, and interneurons in the mouse cortex

1
1. scibot 16 Jan 2025
  
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  DOI: 10.1038/s44318-024-00325-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11730326/
Dec 2024
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Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

1
1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.003
  
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sciencedirect.com/science/article/pii/S1074761324005132
Nov 2024
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The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells

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1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.devcel.2024.10.011
  
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sciencedirect.com/science/article/pii/S1534580724006300
Sep 2024
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Protocol for generating human cortical organoids enriched in outer radial glia by guided differentiation

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.xpro.2024.103280
  
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sciencedirect.com/science/article/pii/S2666166724004453
Jul 2024
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Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells

1
1. scibot 06 Jul 2024
  
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  AB_2896336
  
  DOI: 10.1101/2024.01.01.573836
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802327/
Apr 2024
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Generation of human cerebral organoids with a structured outer subventricular zone

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114031
  
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sciencedirect.com/science/article/pii/S2211124724003590
Mar 2024
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Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113911
  
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sciencedirect.com/science/article/pii/S2211124724002390
Feb 2024
www.biorxiv.org www.biorxiv.org

Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation

1
1. scibot 15 Feb 2024
  
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  DOI: 10.1101/2024.02.07.579368
  
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biorxiv.org/content/10.1101/2024.02.07.579368v1
Nov 2023
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Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

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1. scibot 17 Nov 2023
  
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  RRID:AB_2896336
  
  DOI: 10.1101/2023.11.08.566308
  
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biorxiv.org/content/10.1101/2023.11.08.566308v1
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Highly-parallel production of designer organoids by mosaic patterning of progenitors

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1. scibot 03 Nov 2023
  
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  RRID:AB_2896336
  
  DOI: 10.1101/2023.10.25.564017
  
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biorxiv.org/content/10.1101/2023.10.25.564017v1
Oct 2023
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Tubule jamming in the developing mouse kidney creates cyclical mechanical stresses in nephron-forming niches

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1. scibot 24 Oct 2023
  
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  RRID:AB_2896336
  
  DOI: 10.1101/2022.06.03.494718
  
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biorxiv.org/content/10.1101/2022.06.03.494718v3
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CD38 regulates ovarian function and fecundity via NAD+ metabolism

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107949
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10562803/
Aug 2023
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Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice

2
1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112946
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112946
  
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52.53.155.43/4490579c6cee094eabc4311188483ae5f60f6c44/PIIS2211124723009579-html.html
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TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice

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1. scibot 12 Aug 2023
  
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  DOI: 10.7554/eLife.83451
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10411973/
May 2023
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Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

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1. scibot 24 May 2023
  
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  DOI: 10.1016/j.crmeth.2023.100488
  
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sciencedirect.com/science/article/pii/S266723752300111X
Mar 2023
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Protocol for in vivo and ex vivo assessment of hyperglycemia and islet function in diabetic mice

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1. scibot 01 Mar 2023
  
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  DOI: 10.1016/j.xpro.2023.102133
  
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sciencedirect.com/science/article/pii/S2666166723000916
Jan 2023
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Functional partitioning of transcriptional regulators by patterned charge blocks

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1. scibot 05 Jan 2023
  
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  DOI: 10.1016/j.cell.2022.12.013
  
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sciencedirect.com/science/article/pii/S0092867422015264
Dec 2022
www.cell.com www.cell.com

Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration

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1. scibot 22 Dec 2022
  
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  DOI: 10.1016/j.isci.2022.105683
  
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cell.com/iscience/abstract/S2589-0042(22)01956-3
Sep 2022
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Molecularly defined and functionally distinct cholinergic subnetworks

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1. scibot 22 Sep 2022
  
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  DOI: 10.1016/j.neuron.2022.08.025
  
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sciencedirect.com/science/article/pii/S0896627322007966
Jun 2022
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IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells

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1. scibot 08 Jun 2022
  
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  DOI: 10.1016/j.devcel.2022.05.013
  
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sciencedirect.com/science/article/pii/S1534580722003707