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Lactate couples metabolic state to necroptosis across pathological and physiological conditions

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1. scibot 27 Sep 2026
  
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  DOI: 10.1016/j.cmet.2026.08.022
  
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sciencedirect.com/science/article/pii/S1550413126003748
Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional matrix vesicle replacement partially restores chemo-mechanical coupling in the aged bone niche

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1. scibot 01 Sep 2026
  
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  DOI: 10.1016/j.xcrm.2026.102923
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13522752/
Jul 2026
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A3 adenosine receptor regulates depression-like behaviors through astrocyte-nourished excitatory synapse formation

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1. scibot 17 Jul 2026
  
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  DOI: 10.1016/j.isci.2026.116843
  
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sciencedirect.com/science/article/pii/S2589004226022212
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eIF4E2 deficiency translationally unleashes WRN to sustain DNA repair-mediated chemoresistance

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1. scibot 14 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117686
  
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sciencedirect.com/science/article/pii/S2211124726007643
Feb 2026
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

TGFβ1 Activates Lnc-APUE to Promote Tumor Metastasis via the Alu Element-Driven STAU1-Mediated Decay of CDH1 mRNA

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1. scibot 06 Feb 2026
  
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  DOI: 10.1002/advs.202518731
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518731
Oct 2025
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Dcr1 senses R-loops for RNAPII termination at sites of replication stress and repair pathway choice

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.10.004
  
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sciencedirect.com/science/article/pii/S1097276525008202
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis

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1. scibot 03 Oct 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3405
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12485389/
Aug 2025
jeccr.biomedcentral.com jeccr.biomedcentral.com

TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

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1. scibot 19 Aug 2025
  
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  DOI: 10.1186/s13046-025-03513-5
  
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jeccr.biomedcentral.com/articles/10.1186/s13046-025-03513-5
Jul 2025
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Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.07.002
  
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sciencedirect.com/science/article/pii/S1535610825002739
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Phase transition of WTAP regulates m6A modification of interferon-stimulated genes

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1. scibot 31 May 2025
  
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  DOI: 10.7554/eLife.100601
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12113268/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PDZK1 inhibits MRP2-mediated oxaliplatin chemosensitivity in hepatocellular carcinoma

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1. scibot 24 Apr 2025
  
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  DOI: 10.1038/s41598-025-98085-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12008203/
Nov 2024
www.embopress.org www.embopress.org

Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44318-024-00290-3
  
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embopress.org/doi/10.1038/s44318-024-00290-3
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44318-024-00290-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11649922/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality

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1. scibot 22 Aug 2024
  
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  DOI: 10.7554/eLife.92826
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329274/
May 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

A long-acting FGF21 attenuates metabolic dysfunction-associated steatohepatitis-related fibrosis by modulating NR4A1-mediated Ly6C phenotypic switch in macrophages

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1. scibot 03 May 2024
  
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  DOI: 10.1111/bph.16378
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16378
Mar 2024
www.thno.org www.thno.org

Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma

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1. scibot 30 Mar 2024
  
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  DOI: 10.7150/thno.90322
  
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thno.org/v14p0436.htm
Feb 2024
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ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation

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1. scibot 22 Feb 2024
  
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  DOI: 10.1016/j.devcel.2024.01.026
  
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sciencedirect.com/science/article/pii/S1534580724000467
Jan 2024
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Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101374
  
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sciencedirect.com/science/article/pii/S2666379123006031
Dec 2023
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SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

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1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.molcel.2023.10.042
  
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sciencedirect.com/science/article/pii/S1097276523009139
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nuclear miR-150 enhances hepatic lipid accumulation by targeting RNA transcripts overlapping the PLIN2 promoter

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1. scibot 23 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107837
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10509351/
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Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI

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1. scibot 08 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107749
  
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sciencedirect.com/science/article/pii/S2589004223018266
Jul 2023
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Tet2 acts in the lateral habenula to regulate social preference in mice

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1. scibot 06 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112695
  
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sciencedirect.com/science/article/pii/S2211124723007064
Jun 2023
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Identification of XAF1 as an endogenous AKT inhibitor

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1. scibot 29 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112690
  
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sciencedirect.com/science/article/pii/S2211124723007015
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

cAMP−EPAC−PKCε−RIM1α signaling regulates presynaptic long-term potentiation and motor learning

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1. scibot 12 May 2023
  
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  DOI: 10.7554/eLife.80875
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10171863/
Mar 2023
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METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112150
  
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sciencedirect.com/science/article/pii/S2211124723001614
Feb 2023
link.springer.com link.springer.com

Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6

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1. scibot 02 Feb 2023
  
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  DOI: 10.1007/s12035-023-03232-y
  
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link.springer.com/article/10.1007/s12035-023-03232-y
Dec 2022
www.cell.com www.cell.com

CHD2 maintains spermatogonial self-renewal by promoting chromatin accessibility and mRNA stability

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1. scibot 22 Dec 2022
  
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  DOI: 10.1016/j.isci.2022.105552
  
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cell.com/iscience/abstract/S2589-0042(22)01824-7
Nov 2022
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Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111640
  
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sciencedirect.com/science/article/pii/S221112472201511X