75 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic psychological stress disrupts liver homeostasis by dysregulating oxidative phosphorylation via the PI3K/AKT/FoxO3a axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13068581/
  3. Mar 2026
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    Molecular mechanism underlying the specific RNA recognition of mitochondrial helicase DDX28 and its critical role in mitoribosomal biogenesis
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    sciencedirect.com/science/article/pii/S0969212626000511
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    Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
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    sciencedirect.com/science/article/pii/S009286742600173X
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    Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12958098/
  7. Feb 2026
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    Human papillomavirus 16 E6 oncoprotein promotes up-regulation of RNA-binding protein Sam68 in head and neck cancer
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    MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants
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    sciencedirect.com/science/article/pii/S2211124726000963
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    RAB3GAP2 is a regulator of skeletal muscle endothelial cell proliferation and associated with capillary-to-fiber ratio
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  12. Nov 2025
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    A triple-action PROTAC for wild-type p53 cancer therapy
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  14. Oct 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adjuvants and MHCII modulate the immunogenicity of subdominant epitopes in Plasmodium vivax Duffy binding protein
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    pmc.ncbi.nlm.nih.gov/articles/PMC12547815/
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    Quercetin Increases Expression of Membrane-TRAIL in Glioblastoma Cells Resulting in Apoptosis
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    PNPLA3-I148M is a neomorph that interferes with two primary hepatic triglyceride clearance pathways
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  18. Sep 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The desmosome-intermediate filament system facilitates mechanotransduction at adherens junctions for epithelial homeostasis
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    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation
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    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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  23. Aug 2025
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    The protease-activated receptors are expressed in glioblastoma and differentially modulate adherent versus stem-like growth of LN-18 GBM cells
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    Valproic acid improves the efficacy of oxaliplatin/fluoropyrimidine-based chemotherapy by targeting cancer stem cell via β-Catenin modulation in colorectal cancer
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  26. Jul 2025
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    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    Exposing the DNA methylation-responsive compartment of the leukaemic genome in T-ALL cell lines support its potential as a novel therapeutic target in T-ALL
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    Integrated genetic screening reveals FEN1 as a driver of stemness and temozolomide resistance in glioblastoma
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  30. Jun 2025
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    TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89
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    DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation
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    Quantification of Folded and Misfolded Proinsulin Forms Using Nonreducing SDS-PAGE and Proinsulin-Specific Immunoblotting
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    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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  35. May 2025
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    Microglia-driven inflammation induces progressive tauopathies and synucleinopathies
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    Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
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  39. Apr 2025
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    In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins
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    Treatment of IL-18-binding protein biologics suppresses fibrotic progression in metabolic dysfunction-associated steatohepatitis
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    HMGA1 deficiency: a pathogenic link between tau pathology and insulin resistance
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  43. Mar 2025
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    Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia
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    PIEZO1-dependent mode switch of neuronal migration in heterogeneous microenvironments in the developing brain
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  46. Feb 2025
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    OAS cross-activates RNase L intercellularly through cell-to-cell transfer of 2-5A to spread innate immunity
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    Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium
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    Isolation and Characterization of Antibodies Against Vascular Cell Adhesion Molecule-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction
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    Revisiting phosphoregulation of Cdc25C during M-phase induction
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  54. Dec 2024
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    Clotting Promotes Glioma Growth and Infiltration Through Activation of Focal Adhesion Kinase
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    TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons
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  57. Oct 2024
  58. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ERK1/2 mitogen-activated protein kinase dimerization is essential for the regulation of cell motility
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  59. Sep 2024
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    Mitochondrial bioenergetics and cardiolipin remodeling abnormalities in mitochondrial trifunctional protein deficiency
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    Bacterial pore-forming toxin pneumolysin drives pathogenicity through host extracellular vesicles released during infection
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    A spinal and bulbar muscular atrophy (SBMA) disease-specific human embryonic stem cell (hESC) line, UMICHe002-A/UM197-1
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  64. Aug 2024
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    tRNA-m1A methylation controls the infection of Magnaporthe oryzae by supporting ergosterol biosynthesis
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  66. Jun 2024
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    K29-linked free polyubiquitin chains affect ribosome biogenesis and direct ribosomal proteins to the intranuclear quality control compartment
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  68. May 2024
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    Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss
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    Characterization of a novel HDAC2 pathogenetic variant: a missing puzzle piece for chromatinopathies
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    FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
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  72. Apr 2024
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    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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    A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity
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  75. Mar 2024
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins
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    Unmoving and uninflamed: Characterizing neuroinflammatory dysfunction in the Wistar-Kyoto rat model of depression
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  78. Feb 2024
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    RNF4 prevents genomic instability caused by chronic DNA under-replication
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    Cytotoxin-mediated silk gland organ dysfunction diverts resources to enhance silkworm fecundity by potentiating nutrient-sensing IIS/TOR pathways
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  82. Dec 2023
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    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
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    MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet
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    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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  86. Nov 2023
  87. www.sciencedirect.com www.sciencedirect.com
    ABLs and TMKs are co-receptors for extracellular auxin
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  88. Sep 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a human Tropomyosin 1 knockout iPSC line
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  90. Aug 2023
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    A Zpr1 co-chaperone mediates folding of eukaryotic translation elongation factor 1A via a GTPase cycle
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  92. Jul 2023
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    Generation of a human Tropomyosin 1 knockout iPSC line
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    Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles
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  95. Jun 2023
  96. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Characterization of Hofbauer cell polarization and VEGF localization in human term placenta from active and inactive pregnant individuals
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15741
  97. Apr 2023
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    Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells
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  99. Mar 2023
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    NanoB2 to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET
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  101. Feb 2023
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    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
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  103. Dec 2022
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness
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  105. Oct 2022
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    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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  107. Sep 2022
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    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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  109. Aug 2022
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    Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival
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  111. Jul 2022
  112. yc.mlpla.mil.cn yc.mlpla.mil.cn
    Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
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