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Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.007
  
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sciencedirect.com/science/article/pii/S1074761325004613
Jul 2025
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G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.neuron.2025.06.020
  
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cell.com/neuron/fulltext/S0896-6273(25)00478-7
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Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.018
  
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sciencedirect.com/science/article/pii/S1074761325002870
www.cell.com www.cell.com

TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115972
  
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cell.com/cell-reports/abstract/S2211-1247(25)00743-0
Jun 2025
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Low-grade chronic inflammatory stimulation alleviates α‑syn accumulation in Parkinson's disease by activating autophagy to promote neuronal survival in the Thy1-h[A30P]α-syn mouse model

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.bbr.2025.115703
  
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sciencedirect.com/science/article/pii/S0166432825002906
May 2025
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Tomatidine Ameliorates Diabetes-Induced Cognitive Impairment and Tau Hyperphosphorylation Through the AMPK-TFEB Pathway

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1. scibot 29 May 2025
  
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  DOI: 10.1111/jnc.70087
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70087
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Glycerophospholipid metabolism licenses IgE-mediated mast cell degranulation

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115742
  
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sciencedirect.com/science/article/pii/S2211124725005133
Apr 2025
www.jneurosci.org www.jneurosci.org

Coronin1A regulates the trafficking of alpha synuclein in microglia

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1. scibot 17 Apr 2025
  
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  DOI: 10.1523/JNEUROSCI.1337-24.2025
  
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jneurosci.org/content/45/11/e1337242025
52.53.155.43 52.53.155.43

Lysosome positioning affects NLRP3 inflammasome activation

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1. scibot 03 Apr 2025
  
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  DOI: 10.1101/2025.03.21.644552
  
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52.53.155.43/5e725b42faf6f4894ebfb1897ac6165b04d7cac3/PDF-html.html
Jan 2025
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1-s2.0-S2589004225000641-main-html.html

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1. scibot 23 Jan 2025
  
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  RRID:AB_2923327
  
  DOI: 10.1016/j.isci.2025.111804
  
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52.53.155.43/bb0038ac4731f895cea6a9b8553ebcc516f55d21/1-s2.0-S2589004225000641-main-html.html
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Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection

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1. scibot 17 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115216
  
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sciencedirect.com/science/article/pii/S2211124724015675
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 05 Jan 2025
  
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  DOI: 10.1101/2025.01.01.630988
  
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52.53.155.43/04879393ca39922a7c00ba26ca5d51a54504677a/PDF-html.html
Jul 2024
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Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.jare.2024.07.024
  
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sciencedirect.com/science/article/pii/S2090123224003096
May 2024
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Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114237
  
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sciencedirect.com/science/article/pii/S2211124724005655
Apr 2024
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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114096
  
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sciencedirect.com/science/article/pii/S2211124724004248
Feb 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Aβ plaques in mouse and human brains

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1. scibot 22 Feb 2024
  
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  DOI: 10.1111/jnc.16042
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16042
Jan 2024
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Renal macrophages monitor and remove particles from urine to prevent tubule obstruction

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1. scibot 11 Jan 2024
  
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  RRID:AB_2923327
  
  DOI: 10.1016/j.immuni.2023.12.003
  
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sciencedirect.com/science/article/pii/S1074761323005344
Nov 2023
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Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

1
1. scibot 10 Nov 2023
  
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  RRID:AB_2923327
  
  DOI: 10.1016/j.immuni.2023.10.004
  
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sciencedirect.com/science/article/pii/S1074761323004442
Sep 2023
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A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease

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1. scibot 29 Sep 2023
  
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  DOI: 10.1016/j.stem.2023.07.006
  
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sciencedirect.com/science/article/pii/S1934590923002515
Mar 2023
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PPT1 Regulation Of HSP90α Depalmitoylation Participates In The Pathogenesis Of Hyperandrogenism

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1. scibot 01 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106131
  
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sciencedirect.com/science/article/pii/S2589004223002080
Oct 2022
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In situ cell-type-specific cell-surface proteomic profiling in mice

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1. scibot 11 Oct 2022
  
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  DOI: 10.1016/j.neuron.2022.09.025
  
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sciencedirect.com/science/article/pii/S0896627322008649
Sep 2022
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PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer

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1. scibot 13 Sep 2022
  
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  DOI: 10.1016/j.xcrm.2022.100741
  
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sciencedirect.com/science/article/pii/S2666379122002907