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TNIK overexpression is sufficient for chemoradiation resistance in limited-stage small cell lung cancer

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/1535-7163.MCT-25-0529
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13339944/
May 2026
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A blood-brain barrier-like vascular gate limits immunotherapy efficacy in neuroendocrine cancers

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.cell.2026.04.017
  
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sciencedirect.com/science/article/pii/S0092867426004526
Apr 2026
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Spatial multi-omics unveils the monoclonal origin, neuroendocrine plasticity, and microenvironment niches in combined small-cell lung cancer

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1. scibot 11 Apr 2026
  
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  DOI: 10.1016/j.xcrm.2026.102741
  
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sciencedirect.com/science/article/pii/S2666379126001588
Dec 2025
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KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance

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1. scibot 06 Dec 2025
  
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  DOI: 10.1158/1541-7786.MCR-24-0652
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12133430/
Aug 2025
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Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer

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1. scibot 27 Aug 2025
  
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  DOI: 10.1016/j.devcel.2025.07.023
  
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sciencedirect.com/science/article/pii/S153458072500499X
Jun 2025
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Sequential transcriptional programs underpin activation of hippocampal stem cells

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1. scibot 14 Jun 2025
  
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  DOI: 10.1126/sciadv.adu4523
  
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science.org/doi/10.1126/sciadv.adu4523
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Sequential transcriptional programs underpin activation of hippocampal stem cells

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1. scibot 13 Jun 2025
  
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  DOI: 10.1126/sciadv.adu4523
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12154177/
May 2025
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Viral-mediated Pou5f1 (Oct4) overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.106450
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12088672/
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Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1

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1. scibot 20 May 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-1388
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11534540/
Apr 2025
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Requirements for the neurodevelopmental disorder-associated gene ZNF292 in human cortical interneuron development and function

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115597
  
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sciencedirect.com/science/article/pii/S2211124725003687
Feb 2025
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ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0355
  
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aacrjournals.org/mct/article/23/12/1789/750248/ASCL1-Restrains-ERK1-2-to-Promote-Survival-of-a
Jan 2025
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Phospho-regulation of ASCL1-mediated chromatin opening during cellular reprogramming

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1. scibot 24 Jan 2025
  
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  DOI: 10.1242/dev.204329
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11664170/
Aug 2024
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A human fetal cerebellar map of the late second trimester reveals developmental molecular characteristics and abnormality in trisomy 21

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114586
  
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sciencedirect.com/science/article/pii/S221112472400915X
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

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1. scibot 31 Jul 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0539
  
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2. scibot 31 Jul 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0539
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
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Generation of ASCL1-mCherry knock-in reporter in human embryonic stem cell line, WAe001-A-2E, using CRISPR/Cas9-based gene targeting

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1. scibot 31 Jul 2024
  
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  DOI: 10.1016/j.scr.2024.103500
  
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sciencedirect.com/science/article/pii/S1873506124001983
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Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.012
  
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sciencedirect.com/science/article/pii/S153561082400237X
Jun 2024
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Defining cis-regulatory elements and transcription factors that control human cortical interneuron development

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1. scibot 03 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.109967
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11140214/
May 2024
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CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114286
  
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sciencedirect.com/science/article/pii/S2211124724006144
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Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.ccell.2024.05.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11186085/
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Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.ccell.2024.05.002
  
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sciencedirect.com/science/article/pii/S1535610824001636
Apr 2024
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Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.034
  
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sciencedirect.com/science/article/pii/S1534580724002028
Nov 2023
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Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1

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1. scibot 22 Nov 2023
  
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  DOI: 10.1016/j.xcrm.2023.101282
  
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sciencedirect.com/science/article/pii/S2666379123004767
www.biorxiv.org www.biorxiv.org

ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers

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1. scibot 03 Nov 2023
  
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  DOI: 10.1101/2023.10.24.563645
  
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biorxiv.org/content/10.1101/2023.10.24.563645v1
Mar 2023
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New AAV tools fail to detect Neurod1-mediated neuronal conversion of Müller glia and astrocytes in vivo

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1. scibot 23 Mar 2023
  
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  DOI: 10.1016/j.ebiom.2023.104531
  
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sciencedirect.com/science/article/pii/S2352396423000968
Nov 2022
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FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer

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1. scibot 04 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.10.011
  
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sciencedirect.com/science/article/pii/S1535610822005025
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The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state

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1. scibot 03 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111578
  
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sciencedirect.com/science/article/pii/S2211124722014395