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WEE1 kinase inhibition to overcome acquired resistance to targeted therapies in colorectal cancer

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1. scibot 18 Jun 2026
  
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  RRID:AB_2939025
  
  DOI: 10.1038/s44321-026-00434-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13269805/
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Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s41598-026-46639-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13269758/
Jun 2026
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FET Fusion Oncoproteins Disrupt Physiologic DNA Repair and Create a Targetable Opportunity for ATR Inhibitor Therapy

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1. scibot 05 Jun 2026
  
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  RRID:AB_2939025
  
  DOI: 10.1158/0008-5472.CAN-25-2166
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13223543/
Feb 2026
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Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition

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1. scibot 14 Feb 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-1217
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12900515/
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Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG)

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1. scibot 10 Feb 2026
  
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  DOI: 10.1016/j.neo.2026.101278
  
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sciencedirect.com/science/article/pii/S1476558626000072
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Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer

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1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116941
  
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sciencedirect.com/science/article/pii/S2211124726000197
Nov 2025
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ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin

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1. scibot 23 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116277
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12457572/
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CNOT7 facilitates radiation resistance in colorectal cancer through TRIM21/XRCC6-mediated non-homologous end joining repair

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1. scibot 20 Nov 2025
  
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  RRID:AB_2939025
  
  DOI: 10.1038/s41419-025-08160-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12623751/
Sep 2025
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ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin

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1. scibot 12 Sep 2025
  
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  RRID:AB_2939025
  
  DOI: 10.1016/j.celrep.2025.116277
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12457572/
May 2025
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Mechanisms of chemotherapy failure in refractory/relapsed acute myeloid leukemia: the role of cytarabine resistance and mitochondrial metabolism

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1. scibot 19 May 2025
  
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  RRID:AB_2939025
  
  DOI: 10.1038/s41419-025-07653-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12019594/
www.cell.com www.cell.com

CD47-blocking antibody confers metabolic benefits against obesity

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1. scibot 19 May 2025
  
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  RRID:AB_2939025
  
  DOI: 10.1016/j.xcrm.2025.102089
  
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cell.com/cell-reports-medicine/abstract/S2666-3791(25)00162-4
Apr 2025
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Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer

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1. scibot 16 Apr 2025
  
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  RRID:AB_2939025
  
  DOI: 10.1038/s41419-025-07624-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11992107/
Feb 2024
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IGFBP3 Promotes Resistance to Olaparib via Modulating EGFR Signaling in Advanced Prostate Cancer

1
1. scibot 09 Feb 2024
  
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  RRID:AB_2939025
  
  DOI: 10.1016/j.isci.2024.108984
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10847745/
Jan 2024
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Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence

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1. scibot 05 Jan 2024
  
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  RRID:AB_2939025
  
  DOI: 10.1158/1535-7163.MCT-23-0026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10762335/
Sep 2023
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Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor

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1. scibot 06 Sep 2023
  
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  RRID:AB_2939025
  
  DOI: 10.1158/2767-9764.CRC-23-0304
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10473160/