Hypothesis

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H3K18 lactylation potentiates microglial polarization via the TLR4 pathway in diabetes-induced cognitive impairment

1
1. scibot 14 Feb 2026
  
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  RRID:AB_2941896
  
  DOI: 10.1172/jci.insight.188077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12890480/
May 2025
www.sciencedirect.com www.sciencedirect.com

Metabolic reprogramming through histone lactylation in microglia and macrophages recruits CD8+ T lymphocytes and aggravates spinal cord injury

1
1. scibot 18 May 2025
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.neuron.2025.04.003
  
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sciencedirect.com/science/article/pii/S0896627325002594
Feb 2025
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H4K12 lactylation potentiates mitochondrial oxidative stress via the Foxo1 pathway in diabetes-induced cognitive impairment

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.jare.2025.02.020
  
  Resource: (PTM BIO Cat# PTM-1411RM, RRID:AB_2941896)
  
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sciencedirect.com/science/article/pii/S2090123225001183
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Lactate shuttling links histone lactylation to adult hippocampal neurogenesis in mice

7
1. scibot 07 Feb 2025
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.devcel.2024.12.021
  
  Resource: (PTM BIO Cat# PTM-1411RM, RRID:AB_2941896)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2941896
  
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  RRID:AB_2941896
2. scibot 06 Feb 2025
  
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  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
3. scibot 05 Feb 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
4. scibot 04 Feb 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
5. scibot 03 Feb 2025
  
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  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
6. scibot 02 Feb 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
7. scibot 01 Feb 2025
  
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  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
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URL

sciencedirect.com/science/article/pii/S1534580724007603
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Lactate shuttling links histone lactylation to adult hippocampal neurogenesis in mice

25
1. scibot 31 Jan 2025
  
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  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
2. scibot 30 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
3. scibot 29 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
4. scibot 28 Jan 2025
  
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  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
5. scibot 27 Jan 2025
  
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  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
6. scibot 26 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
7. scibot 25 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
8. scibot 24 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
9. scibot 23 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
10. scibot 22 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
11. scibot 21 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
12. scibot 20 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
13. scibot 19 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
14. scibot 18 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
15. scibot 17 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
16. scibot 16 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
17. scibot 15 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
18. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
19. scibot 13 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
20. scibot 12 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
21. scibot 11 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
22. scibot 10 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
23. scibot 09 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
24. scibot 08 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
25. scibot 07 Jan 2025
  
  in Public
  
  RRID:AB_2941896
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2941896
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sciencedirect.com/science/article/pii/S1534580724007603
Nov 2024
www.sciencedirect.com www.sciencedirect.com

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.cmet.2024.10.015
  
  Resource: (PTM BIO Cat# PTM-1411RM, RRID:AB_2941896)
  
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  SciCrunch record: RRID:AB_2941896
  
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sciencedirect.com/science/article/pii/S155041312400411X
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis

1
1. scibot 05 Oct 2024
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.isci.2024.110911
  
  Resource: (PTM BIO Cat# PTM-1411RM, RRID:AB_2941896)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11440250/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma

1
1. scibot 14 Jul 2024
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.isci.2024.110188
  
  Resource: (PTM BIO Cat# PTM-1411RM, RRID:AB_2941896)
  
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  SciCrunch record: RRID:AB_2941896
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233973/
Dec 2023
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Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells

1
1. scibot 23 Dec 2023
  
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  RRID:AB_2941896
  
  DOI: 10.1016/j.isci.2023.108645
  
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sciencedirect.com/science/article/pii/S2589004223027220
Nov 2023
52.53.155.43 52.53.155.43

Progesterone activates histone lactylation-Hif1α-glycolysis feedback loop to promote decidualization

2
1. scibot 18 Nov 2023
  
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  AB_2941896
  
  DOI: 10.1210/endocr/bqad169
  
  Resource: AB_2941896
  
  Curator: @scibot
  
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2. scibot 18 Nov 2023
  
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  AB_2941896
  
  DOI: 10.1210/endocr/bqad169
  
  Resource: AB_2941896
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2941896
  
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52.53.155.43/a32f66b9b11d3fe5e0af257f387c02b0aece4ce8/bqad169 (2)-html.html

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