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Programmed DNA breaks drive chromatin reconfiguration and facilitate transcriptional potentiation at neuronal early response genes

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1. scibot 24 Oct 2026
  
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  DOI: 10.1016/j.celrep.2026.118186
  
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sciencedirect.com/science/article/pii/S2211124726012659
Oct 2026
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TDP2-mediated DNA repair regulates the dynamics of neuronal early response gene transcription and cortical neuron connectivity

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1. scibot 15 Oct 2026
  
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  DOI: 10.1016/j.celrep.2026.118152
  
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sciencedirect.com/science/article/pii/S2211124726012313
Jun 2026
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The heat shock transcription factor, HSF1, stimulates the catalytic engagement of topoisomerase IIβ over topoisomerase IIα

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1. scibot 04 Jun 2026
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.molcel.2026.05.014
  
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sciencedirect.com/science/article/pii/S1097276526003205
Jan 2026
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CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells

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1. scibot 27 Jan 2026
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.isci.2026.114646
  
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sciencedirect.com/science/article/pii/S2589004226000210
Nov 2025
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A role for human senataxin in contending with pausing and backtracking during transcript elongation

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.molcel.2025.10.019
  
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sciencedirect.com/science/article/pii/S1097276525008603
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma

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1. scibot 07 Sep 2023
  
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  DOI: 10.1158/1078-0432.CCR-22-3897
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10472104/
Feb 2023
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SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS

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1. scibot 03 Feb 2023
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.stem.2023.01.005
  
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sciencedirect.com/science/article/pii/S193459092300005X
Jan 2023
www.cell.com www.cell.com

Loss of epigenetic information as a cause of mammalian aging

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.cell.2022.12.027
  
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cell.com/cell/fulltext/S0092-8674(22)01570-7
Oct 2022
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Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks

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1. scibot 07 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.012
  
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sciencedirect.com/science/article/pii/S1097276522009017
Aug 2022
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Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop

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1. scibot 30 Aug 2022
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.isci.2022.104944
  
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sciencedirect.com/science/article/pii/S2589004222012160
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells

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1. scibot 16 Feb 2022
  
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  RRID:AB_297814
  
  DOI: 10.3390/ijms23031116
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8835362/
Aug 2021
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

Untitled document

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1. scibot 07 Aug 2021
  
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  RRID:AB_297814
  
  DOI: 10.1186/s12915-017-0453-8
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0453-8
Jul 2021
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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

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1. scibot 09 Jul 2021
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.molcel.2021.06.016
  
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sciencedirect.com/science/article/pii/S1097276521004962
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors

1
1. scibot 22 Apr 2021
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.ccell.2020.10.009
  
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  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_297814
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ncbi.nlm.nih.gov/pmc/articles/PMC8455074/
Feb 2021
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Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity

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1. scibot 25 Feb 2021
  
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  DOI: 10.7554/eLife.53447
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7089766/
Jan 2020
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

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1. scibot 13 Jan 2020
  
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  AB_297814
  
  DOI: 10.1016/j.molcel.2019.06.043
  
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  RRID:AB_297814 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519305003
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The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

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1. scibot 13 Jan 2020
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.celrep.2019.08.070
  
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  Curator: @ethanbadger
  
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  RRID:AB_297814 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719311258
onlinelibrary.wiley.com onlinelibrary.wiley.com

Ultrastructure of spermiogenesis and the distribution of spermatozoal nuclear histones in the Japanese mantis shrimp, Oratosquilla oratoria (Crustacea: Stomatopoda)

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1. scibot 13 Jan 2020
  
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  DOI: 10.1002/jmor.21008
  
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  Curator: @Naa003
  
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  RRID:AB_297814 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1002/jmor.21008
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Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

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1. scibot 13 Jan 2020
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.molcel.2019.07.037
  
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  RRID:AB_297814 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519305921
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.01.083
  
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  RRID:AB_297814 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719301123
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_297814
  
  DOI: 10.1016/j.celrep.2019.02.088
  
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sciencedirect.com/science/article/pii/S2211124719302748
Nov 2018
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The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1097276518307573
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Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518305586
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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1534580718305975
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_297814
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5721592/