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A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.014
  
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sciencedirect.com:5037/science/article/pii/S0092867425013108
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Zika virus remodels and hijacks IGF2BP2 ribonucleoprotein complex to promote viral replication organelle biogenesis

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1. scibot 26 Nov 2024
  
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  DOI: 10.7554/eLife.94347
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11578589/
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PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization

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1. scibot 21 Nov 2024
  
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  DOI: 10.1016/j.molcel.2024.10.028
  
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sciencedirect.com/science/article/pii/S1097276524008682
May 2024
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Autophagy preferentially degrades non-fibrillar polyQ aggregates

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.molcel.2024.04.018
  
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sciencedirect.com/science/article/pii/S1097276524003836
Aug 2023
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Senescent cells form nuclear foci that contain the 26S proteasome

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  DOI: 10.1016/j.celrep.2023.112880
  
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sciencedirect.com/science/article/pii/S2211124723008914
Mar 2023
52.53.155.43 52.53.155.43

Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase

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1. scibot 16 Mar 2023
  
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  DOI: 10.1101/2023.01.31.526464
  
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52.53.155.43/56dd9657520d89efd227b99f30a1871711d5fdb7/2023.01.31.526464v1.full-html.html
Feb 2023
www.nature.com www.nature.com

The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system

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1. scibot 04 Feb 2023
  
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  DOI: 10.1038/s41467-023-36058-2
  
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nature.com/articles/s41467-023-36058-2
Dec 2022
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Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA

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1. scibot 20 Dec 2022
  
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  DOI: 10.1016/j.molcel.2022.11.022
  
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sciencedirect.com/science/article/pii/S1097276522011352
Oct 2022
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Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111536
  
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sciencedirect.com/science/article/pii/S2211124722013924
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Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes

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1. scibot 18 Oct 2022
  
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  DOI: 10.1016/j.cmet.2022.09.022
  
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sciencedirect.com/science/article/pii/S1550413122004120
Aug 2022
www.embopress.org www.embopress.org

Regulation of membrane fluidity by RNF145-triggered degradation of the lipid hydrolase ADIPOR2

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1. scibot 23 Aug 2022
  
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  DOI: 10.15252/embj.2022110777
  
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embopress.org/doi/10.15252/embj.2022110777
Jun 2022
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The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability

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1. scibot 10 Jun 2022
  
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  DOI: 10.1016/j.cell.2022.05.008
  
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sciencedirect.com/science/article/pii/S009286742200592X
Mar 2022
www.embopress.org www.embopress.org

K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation

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1. scibot 31 Mar 2022
  
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  DOI: 10.15252/embj.2021110145
  
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embopress.org/doi/abs/10.15252/embj.2021110145
Feb 2022
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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis

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1. scibot 04 Feb 2022
  
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  DOI: 10.1016/j.cmet.2022.01.004
  
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sciencedirect.com/science/article/pii/S1550413122000043
Oct 2021
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USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork

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1. scibot 13 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109819
  
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sciencedirect.com/science/article/pii/S2211124721012833
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 13 Aug 2021
  
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  DOI: 10.1016/j.celrep.2019.04.025
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6506760/
Jul 2021
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Neuronal VCP loss of function recapitulates FTLD-TDP pathology

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1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109399
  
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sciencedirect.com/science/article/pii/S221112472100797X
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming

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1. scibot 06 Apr 2021
  
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  DOI: 10.7554/eLife.64527
  
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  RRID:AB_298039 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC8012061/
Dec 2020
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Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals

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1. scibot 16 Dec 2020
  
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  DOI: 10.1016/j.cels.2020.11.007
  
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sciencedirect.com/science/article/pii/S2405471220304580
Jan 2020
www.embopress.org www.embopress.org

A protein quality control pathway regulated by linear ubiquitination

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1. scibot 13 Jan 2020
  
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  DOI: 10.15252/embj.2018100730
  
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embopress.org/doi/10.15252/embj.2018100730
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Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes

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1. scibot 13 Jan 2020
  
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  DOI: 10.15252/embr.201947728
  
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embopress.org/doi/full/10.15252/embr.201947728
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Untitled document

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  DOI: 10.1016/j.celrep.2019.01.103
  
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sciencedirect.com/science/article/pii/S2211124719301408
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Untitled document

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  DOI: 10.1016/j.celrep.2019.04.025
  
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sciencedirect.com/science/article/pii/S2211124719304905
Nov 2018
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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1550413117305703
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ZFAND1 Recruits p97 and the 26S Proteasome to Promote the Clearance of Arsenite-Induced Stress Granules

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518303174
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Excitatory and Inhibitory Neurons Utilize Different Ca2+ Sensors and Sources to Regulate Spontaneous Release

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0896627318303301
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The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair

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sciencedirect.com/science/article/pii/S109727651830100X