75 Matching Annotations
  1. Apr 2024
  2. www.nature.com www.nature.com
    Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies
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    1. scibot 18 Apr 2024
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      DOI: 10.1038/s41467-024-47569-x

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  3. www.sciencedirect.com www.sciencedirect.com
    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114067

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    sciencedirect.com/science/article/pii/S2211124724003954
  4. Mar 2024
  5. www.sciencedirect.com www.sciencedirect.com
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
    1
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    sciencedirect.com/science/article/pii/S0925443924001200
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    Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway
    1
    1. scibot 27 Mar 2024
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    sciencedirect.com/science/article/pii/S1534580724001424
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    OPA1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1
    3
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109164

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      DOI: 10.1016/j.isci.2024.109164

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    3. scibot 02 Mar 2024
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      DOI: 10.1016/j.isci.2024.109164

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    sciencedirect.com/science/article/pii/S2589004224003857
  8. Feb 2024
  9. 52.53.155.43 52.53.155.43
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
    2
    1. scibot 29 Feb 2024
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  10. Jan 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Inosine induces stemness features in CAR-T cells and enhances potency
    1
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    sciencedirect.com/science/article/pii/S1535610824000084
  12. Nov 2023
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    Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.xcrm.2023.101264

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    sciencedirect.com/science/article/pii/S266637912300441X
  14. Sep 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout
    1
    1. scibot 22 Sep 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10507162/
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    Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease
    1
    1. scibot 19 Sep 2023
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    sciencedirect.com/science/article/pii/S0003986123002102
  17. Aug 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10409763/
  19. Jul 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.cmet.2023.06.015

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    sciencedirect.com/science/article/abs/pii/S1550413123002255
  21. Jun 2023
  22. www.embopress.org www.embopress.org
    Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV
    1
    1. scibot 06 Jun 2023
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      DOI: 10.15252/embr.202256430

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    embopress.org/doi/10.15252/embr.202256430
  23. Apr 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles
    1
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.cmet.2023.03.016

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    sciencedirect.com/science/article/pii/S1550413123000943
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    The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
    1
    1. scibot 04 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112332

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    sciencedirect.com/science/article/pii/S2211124723003431
  26. Mar 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency
    1
    1. scibot 10 Mar 2023
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      DOI: 10.7554/eLife.68047

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    ncbi.nlm.nih.gov/pmc/articles/PMC9991045/
  28. Oct 2022
  29. academic.oup.com academic.oup.com
    Premature ovarian insufficiency in CLPB deficiency: transcriptomic, proteomic and phenotypic insights
    1
    1. scibot 27 Oct 2022
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      DOI: 10.1210/clinem/dgac528

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac528/6694194
  30. www.sciencedirect.com www.sciencedirect.com
    Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.cmet.2022.09.005

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    sciencedirect.com/science/article/pii/S1550413122003953
  31. Sep 2022
  32. www.sciencedirect.com www.sciencedirect.com
    OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy
    1
    1. scibot 16 Sep 2022
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      DOI: 10.1016/j.cmet.2022.08.017

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    sciencedirect.com/science/article/pii/S1550413122003606
  33. Aug 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia
    1
    1. scibot 27 Aug 2022
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      DOI: 10.1016/j.heliyon.2022.e10371

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    sciencedirect.com/science/article/pii/S2405844022016590
  35. Jul 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins
    1
    1. scibot 12 Jul 2022
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      DOI: 10.3390/cancers14133129

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    ncbi.nlm.nih.gov/pmc/articles/PMC9265124/
  37. Mar 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory Chain
    1
    1. scibot 18 Mar 2022
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      DOI: 10.3389/fcell.2022.786268

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    ncbi.nlm.nih.gov/pmc/articles/PMC8921082/
  39. academic.oup.com academic.oup.com
    Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease
    1
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      DOI: 10.1093/hmg/ddac002

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddac002/6504746
  40. Jan 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
    1
    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.020

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    sciencedirect.com/science/article/pii/S1534580721010406
  42. Dec 2021
  43. link.springer.com link.springer.com
    Expanding the clinical phenotype of IARS2-related mitochondrial disease
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1186/s12881-018-0709-3

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    link.springer.com/article/10.1186/s12881-018-0709-3
  44. www.sciencedirect.com www.sciencedirect.com
    Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I
    1
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      DOI: 10.1016/j.chembiol.2021.11.002

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    sciencedirect.com/science/article/pii/S2451945621004797
  45. Sep 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival
    1
    1. scibot 16 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109704

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    sciencedirect.com/science/article/pii/S2211124721011517
  47. Aug 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation
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      DOI: 10.1016/j.celrep.2021.109565

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    sciencedirect.com/science/article/pii/S2211124721009992
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
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      DOI: 10.7554/eLife.59828

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    ncbi.nlm.nih.gov/pmc/articles/PMC8331182/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.11.080

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    ncbi.nlm.nih.gov/pmc/articles/PMC6315286/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6286155/
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    The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock
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      DOI: 10.1016/j.cell.2021.07.001

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    sciencedirect.com/science/article/pii/S0092867421008278
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6233262/
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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      DOI: 10.1016/j.molcel.2019.03.021

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    sciencedirect.com/science/article/pii/S1097276519302254
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    sciencedirect.com/science/article/pii/S2211124718316474
  56. Jul 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells
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      DOI: 10.1016/j.cmet.2018.10.014

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    sciencedirect.com/science/article/pii/S1550413118306466
  58. www.nature.com www.nature.com
    α-Ketoglutarate links p53 to cell fate during tumour suppression
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      DOI: 10.1038/s41586-019-1577-5

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    nature.com/articles/s41586-019-1577-5
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    sciencedirect.com/science/article/pii/S2405471218300085
  60. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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      DOI: 10.1002/cptx.56

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  61. May 2021
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    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease
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  64. Apr 2021
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    A High-Density Human Mitochondrial Proximity Interaction Network
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    Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth
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    NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate
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    A membrane arm of mitochondrial complex I sufficient to promote respirasome formation
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  69. Mar 2021
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    The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism
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  71. Feb 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niche-derived soluble DLK1 promotes glioma growth
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  73. www.cell.com www.cell.com
    Fatal Perinatal Mitochondrial Cardiac Failure Caused by Recurrent De Novo Duplications in the ATAD3 Locus
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  74. Oct 2020
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niche-derived soluble DLK1 promotes glioma growth
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  76. Sep 2020
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    Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
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    Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I
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    Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
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    Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reactive oxygen species oxidize STING and suppress interferon production
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  83. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Protocol for the Analysis of Yeast and Human Mitochondrial Respiratory Chain Complexes and Supercomplexes by Blue Native Electrophoresis
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  84. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Disease‐specific phenotypes in iPSC‐derived neural stem cells with POLG mutations
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      Anti‐SDHA

      DOI: 10.15252/emmm.202012146

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  85. Jan 2020
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    Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions
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      DOI: 10.1016/j.cmet.2019.08.019

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    sciencedirect.com/science/article/pii/S1550413119304486
  87. www.jci.org www.jci.org
    Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice
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      DOI: 10.1172/JCI127277

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  88. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718318710
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of bioenergetics provides novel insights into recruitment of PINK1‐dependent neuronal mitophagy
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      DOI: 10.1111/jnc.14667

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14667
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    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality
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      DOI: 10.1016/j.ccell.2019.03.014

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    Mitohormesis Primes Tumor Invasion and Metastasis
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  92. Nov 2018
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  94. www.cell.com www.cell.com
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  96. Nov 2017
  97. www.sciencedirect.com www.sciencedirect.com
    Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex
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    A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I–III
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    Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability
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    Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
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