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145 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The proteostatic landscape of healthy human oocytes

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1. scibot 21 Aug 2025
  
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  DOI: 10.1038/s44318-025-00493-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12361380/
elifesciences.org elifesciences.org

Transcriptional dynamics uncover the role of BNIP3 in mitophagy during muscle remodeling in Drosophila

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1. scibot 15 Aug 2025
  
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  DOI: 10.7554/eLife.105834
  
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elifesciences.org/articles/105834
52.53.155.43 52.53.155.43

41467_2025_56346_MOESM1_ESM-html.html

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  DOI: 10.1038/s41467-025-56346-3
  
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52.53.155.43/0cdd1395338fbad58a2c837457ae32b83153d0d5/41467_2025_56346_MOESM1_ESM-html.html
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I–III

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.cmet.2017.03.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12285277/
52.53.155.43 52.53.155.43

41467_2025_56346_MOESM1_ESM (1)-html.html

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  DOI: 10.1038/s41467-025-56346-3
  
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52.53.155.43/1761484a67730362675820c7685649e27bb2d182/41467_2025_56346_MOESM1_ESM (1)-html.html
www.cell.com www.cell.com

Controlling mitochondrial membrane architecture via MIC60 determines viral replication to promote anti-viral immunity

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115922
  
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cell.com/cell-reports/abstract/S2211-1247(25)00693-X
Jun 2025
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PRPS activity tunes redox homeostasis in Myc-driven lymphoma

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.redox.2025.103649
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Drosophila Clu ribonucleoprotein particle dynamics rely on the availability of functional Clu and translating ribosomes

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1. scibot 12 Jun 2025
  
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  DOI: 10.1242/jcs.263730
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12136168/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 11 Jun 2025
  
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  DOI: 10.1111/bph.70085
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70085
Apr 2025
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MIA40 suppresses cell death induced by apoptosis-inducing factor 1

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1. scibot 19 Apr 2025
  
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  DOI: 10.1038/s44319-025-00406-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11976965/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Ectopic protein lysine methacrylation contributes to defects caused by loss of HIBCH or ECHS1

1
1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115379
  
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sciencedirect.com/science/article/pii/S2211124725001500
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Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia

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1. scibot 04 Mar 2025
  
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  DOI: 10.1002/advs.202414260
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12021055/
Feb 2025
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MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling

1
1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.017
  
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sciencedirect.com/science/article/pii/S1550413125000178
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Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma

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1. scibot 11 Feb 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0187
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11803400/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A transcription network underlies the dual genomic coordination of mitochondrial biogenesis

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1. scibot 04 Jan 2025
  
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  DOI: 10.7554/eLife.96536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11677238/
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Glycogen homeostasis and mitochondrial DNA expression require motor neuron to muscle TGF-β/Activin signaling in Drosophila

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111611
  
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sciencedirect.com/science/article/pii/S2589004224028384
Dec 2024
www.cell.com www.cell.com

Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.12.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Integrated multi-omics analysis of zinc-finger proteins uncovers roles in RNA regulation

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1. scibot 13 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.08.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11633308/
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OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase

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1. scibot 05 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115038
  
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sciencedirect.com/science/article/pii/S2211124724013895
Nov 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways

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1. scibot 07 Nov 2024
  
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  DOI: 10.26508/lsa.202403038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11472510/
Oct 2024
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Transgenic sensors reveal compartment-specific effects of aggregation-prone proteins on subcellular proteostasis during aging

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1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.crmeth.2024.100875
  
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sciencedirect.com/science/article/pii/S2667237524002583
Aug 2024
www.cell.com www.cell.com

SLC25A48 controls mitochondrial choline import and metabolism

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cmet.2024.07.010
  
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cell.com/cell-metabolism/fulltext/S1550-4131(24)00281-X
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BCL2L13 at Endoplasmic Reticulum-Mitochondria Contact Sites Regulates Calcium Homeostasis to Maintain Skeletal Muscle Function

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110510
  
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sciencedirect.com/science/article/pii/S2589004224017358
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CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex

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1. scibot 18 Aug 2024
  
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  DOI: 10.1083/jcb.202305087
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10818064/
52.53.155.43 52.53.155.43

PMC10174194 S1 Table-html.html

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  DOI: 10.1083/jcb.202211074
  
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52.53.155.43/08461ce6dd864961f351a1d5fb7d3c9b768910e9/PMC10174194 S1 Table-html.html
Jul 2024
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The extracellular matrix integrates mitochondrial homeostasis

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.05.057
  
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sciencedirect.com/science/article/pii/S009286742400638X
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Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8

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1. scibot 16 Jul 2024
  
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  DOI: 10.1242/dmm.043174
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7328144/
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Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End

2
1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.devcel.2020.02.006
  
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  DOI: 10.1016/j.devcel.2020.02.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7170007/
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Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation

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1. scibot 10 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110185
  
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sciencedirect.com/science/article/pii/S258900422401410X
Jun 2024
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MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.017
  
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sciencedirect.com/science/article/pii/S0092867424005269
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TRABD modulates mitochondrial homeostasis and tissue integrity

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  DOI: 10.1016/j.celrep.2024.114304
  
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sciencedirect.com/science/article/pii/S2211124724006326
Apr 2024
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Multi-omic profiling reveals the endogenous and neoplastic responses to immunotherapies in cutaneous T cell lymphoma

2
1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101527
  
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  DOI: 10.1016/j.xcrm.2024.101527
  
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sciencedirect.com/science/article/pii/S2666379124001964
Mar 2024
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Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway

1
1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.devcel.2024.03.002
  
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sciencedirect.com/science/article/pii/S1534580724001424
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

C17orf80 binds the mitochondrial genome to promote its replication

1
1. scibot 10 Mar 2024
  
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  DOI: 10.1083/jcb.202302037
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10484793/
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OPA1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1

3
1. scibot 07 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109164
  
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2. scibot 07 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109164
  
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mtDNA extramitochondrial replication mediates mitochondrial defect effects

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Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding

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Inosine induces stemness features in CAR-T cells and enhances potency

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Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation

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Partial loss of MCU mitigates pathology in vivo across a diverse range of neurodegenerative disease models

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Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism

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Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders

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PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development

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FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo

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Jul 2023
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Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage

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PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics

1
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Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation

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Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice

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May 2023
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IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

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Mar 2023
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Switching ubiquitous and muscle-specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine-tunes complex IV activity

1
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Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest

1
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Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration

1
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Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency

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Feb 2023
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Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14)

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Dec 2022
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Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy

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GABA regulates IL-1β production in macrophages

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Oct 2022
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Spatial epitope barcoding reveals clonal tumor patch behaviors

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MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux

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Aug 2022
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Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity

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Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

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Jun 2022
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Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

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Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

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Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia

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Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia

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May 2022
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Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation

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Mar 2022
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Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models

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Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains

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Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy

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Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease

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academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddac002/6504746
Feb 2022
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Mitochondrial Localization of CB1 in Progesterone-producing Cells of Ovarian Interstitial Glands of Adult Mice - Anussara Kamnate, Juthathip Sirisin, Masahiko Watanabe, Hisatake Kondo, Wiphawi Hipkaeo, Surang Chomphoo, 2021

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  DOI: 10.1369/00221554211063516
  
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NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis

1
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Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

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A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy

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Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing

1
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Glutamate metabolism directs energetic trade-offs to shape host-pathogen susceptibility in Drosophila

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UQCRC1 engages cytochrome c for neuronal apoptotic cell death

1
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Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival

1
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Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation

1
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ncbi.nlm.nih.gov/pmc/articles/PMC6315286/
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ncbi.nlm.nih.gov/pmc/articles/PMC6286155/
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Untitled document

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Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo

1
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Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

1
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Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

1
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Untitled document

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Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase

3
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ncbi.nlm.nih.gov/pmc/articles/PMC5059426/
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ncbi.nlm.nih.gov/pmc/articles/PMC6331342/
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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

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Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism

1
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sciencedirect.com/science/article/pii/S1550413121000036
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Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth

1
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Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output

1
1. scibot 24 Apr 2021
  
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Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis

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Functional interpretation of ATAD3A variants in neuro-mitochondrial phenotypes

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8042885/
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Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress

1
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A membrane arm of mitochondrial complex I sufficient to promote respirasome formation

1
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A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients

1
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Comparative analysis of CI- and CIV-containing respiratory supercomplexes at single-cell resolution

2
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sciencedirect.com/science/article/pii/S2667237521000023
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PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers

1
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cell.com/cell-metabolism/abstract/S1550-4131(18)30567-9
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species‐mediated mitochondrial injury

1
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  DOI: 10.1096/fj.201902459R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902459R
Jan 2021
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Ecd promotes U5 snRNP maturation and Prp8 stability

1
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ncbi.nlm.nih.gov/pmc/articles/PMC7897482/
Nov 2020
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Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes

1
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ncbi.nlm.nih.gov/pmc/articles/PMC7605714/
Sep 2020
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A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins

1
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  DOI: 10.1523/JNEUROSCI.1808-19.2019
  
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jneurosci.org/content/40/1/107
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Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis

1
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  DOI: 10.1016/j.celrep.2020.107607
  
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ATF4-Induced Warburg Metabolism Drives Over-Proliferation in Drosophila

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Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End

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Protocol for the Analysis of Yeast and Human Mitochondrial Respiratory Chain Complexes and Supercomplexes by Blue Native Electrophoresis

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Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27

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Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

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Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I

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Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8

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The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models

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Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila

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Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

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Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A

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Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

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Repressive Gene Regulation Synchronizes Development with Cellular Metabolism

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A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production

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Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo

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Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance

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The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

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Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain

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Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin

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PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions

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Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration

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Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria

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A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers

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A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I–III

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In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation

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Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number

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