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  1. May 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
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    1. scibot 19 May 2022
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      DOI: 10.1016/j.celrep.2022.110830

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    sciencedirect.com/science/article/pii/S2211124722006015
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    Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts
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      DOI: 10.1016/j.celrep.2022.110821

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    sciencedirect.com/science/article/pii/S2211124722005927
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    Single-cell analysis of human testis aging and correlation with elevated body mass index
    1
    1. scibot 05 May 2022
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      DOI: 10.1016/j.devcel.2022.04.004

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    sciencedirect.com/science/article/pii/S1534580722002441
  5. Apr 2022
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    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.molcel.2022.03.030

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    sciencedirect.com/science/article/pii/S1097276522002684
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.molcel.2022.03.031

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    sciencedirect.com/science/article/pii/S1097276522002696
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    Microtubules promote the non-cell autonomous action of microRNAs by inhibiting their cytoplasmic loading onto ARGONAUTE1 in Arabidopsis
    1
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      DOI: 10.1016/j.devcel.2022.03.015

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    sciencedirect.com/science/article/pii/S153458072200209X
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    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
    2
    1. scibot 08 Apr 2022
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      DOI: 10.1016/j.isci.2022.104142

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      DOI: 10.1016/j.isci.2022.104142

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    sciencedirect.com/science/article/pii/S2589004222004126
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    CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
    1
    1. scibot 07 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110626

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    sciencedirect.com/science/article/pii/S2211124722003746
  11. aacrjournals.org aacrjournals.org
    PGC1α/β EXPRESSION PREDICTS THERAPEUTIC RESPONSE TO OXIDATIVE PHOSPHORYLATION INHIBITION IN OVARIAN CANCER
    1
    1. scibot 05 Apr 2022
      RRID:AB_302613

      DOI: 10.1158/0008-5472.CAN-21-1223

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    aacrjournals.org/cancerres/article/82/7/1423/694053/PGC1-Expression-Predicts-Therapeutic-Response-to
  12. Mar 2022
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TFIIH complex is required to establish and maintain mitotic chromosome structure
    1
    1. scibot 31 Mar 2022
      RRID:AB_302613

      DOI: 10.7554/eLife.75475

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    ncbi.nlm.nih.gov/pmc/articles/PMC8956287/
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    Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
    1
    1. scibot 31 Mar 2022
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      DOI: 10.1016/j.molcel.2022.03.004

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    sciencedirect.com/science/article/pii/S1097276522002131
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein
    1
    1. scibot 26 Mar 2022
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      DOI: 10.1016/j.isci.2022.104040

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    ncbi.nlm.nih.gov/pmc/articles/PMC8938288/
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    Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development
    1
    1. scibot 25 Mar 2022
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      DOI: 10.1016/j.cell.2022.02.022

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    sciencedirect.com/science/article/pii/S0092867422002021
  17. www.sciencedirect.com www.sciencedirect.com
    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
    1
    1. scibot 23 Mar 2022
      RRID:AB_302613

      DOI: 10.1016/j.celrep.2022.110538

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    sciencedirect.com/science/article/pii/S2211124722002790
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1016/j.isci.2022.104008

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    ncbi.nlm.nih.gov/pmc/articles/PMC8931362/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions
    1
    1. scibot 23 Mar 2022
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      DOI: 10.7554/eLife.73524

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    ncbi.nlm.nih.gov/pmc/articles/PMC8933006/
  20. www.sciencedirect.com www.sciencedirect.com
    A trio of ubiquitin ligases sequentially drives ubiquitylation and autophagic degradation of dysfunctional yeast proteasomes
    1
    1. scibot 18 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110535

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    sciencedirect.com/science/article/pii/S2211124722002765
  21. www.sciencedirect.com www.sciencedirect.com
    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.molcel.2022.02.006

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    sciencedirect.com/science/article/pii/S1097276522001113
  22. www.sciencedirect.com www.sciencedirect.com
    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.isci.2022.103813

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    sciencedirect.com/science/article/pii/S2589004222000839
  23. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
    1
    1. scibot 02 Mar 2022
      AB_1791

      DOI: 10.1016/j.celrep.2022.110457

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    sciencedirect.com/science/article/pii/S221112472200184X
  24. Feb 2022
  25. elifesciences.org elifesciences.org
    Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
    1
    1. scibot 19 Feb 2022
      RRID:AB_302613

      DOI: 10.7554/eLife.70714

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    elifesciences.org/articles/70714
  26. www.sciencedirect.com www.sciencedirect.com
    Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth
    1
    1. scibot 13 Feb 2022
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      DOI: 10.1016/j.medj.2021.12.008

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    sciencedirect.com/science/article/pii/S2666634021004098
  27. www.sciencedirect.com www.sciencedirect.com
    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.molcel.2022.01.002

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    sciencedirect.com/science/article/pii/S1097276522000028
  28. Jan 2022
  29. www.cell.com www.cell.com
    Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
    1
    1. scibot 26 Jan 2022
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      DOI: 10.1016/j.molcel.2021.12.023

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    cell.com/molecular-cell/fulltext/S1097-2765(21)01085-6
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
    1
    1. scibot 22 Jan 2022
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      DOI: 10.7554/eLife.72867

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    ncbi.nlm.nih.gov/pmc/articles/PMC8765754/
  31. link.springer.com link.springer.com
    Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis
    1
    1. scibot 22 Jan 2022
      AB_302613

      DOI: 10.1186/s12915-021-01225-8

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    link.springer.com/article/10.1186/s12915-021-01225-8
  32. link.springer.com link.springer.com
    Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome
    1
    1. scibot 08 Jan 2022
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      DOI: 10.1186/s13072-021-00433-4

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    link.springer.com/article/10.1186/s13072-021-00433-4
  33. Dec 2021
  34. www.sciencedirect.com www.sciencedirect.com
    EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion
    1
    1. scibot 28 Dec 2021
      RRID:AB_302613

      DOI: 10.1016/j.cell.2021.12.005

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    sciencedirect.com/science/article/pii/S0092867421014276
  35. www.sciencedirect.com www.sciencedirect.com
    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
    1
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      DOI: 10.1016/j.celrep.2021.110138

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    sciencedirect.com/science/article/pii/S221112472101634X
  36. www-sciencedirect-com.proxy.library.vcu.edu www-sciencedirect-com.proxy.library.vcu.edu
    Potent macrocycle inhibitors of the human SAGA deubiquitinating module
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    1. scibot 22 Dec 2021
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      DOI: 10.1016/j.chembiol.2021.12.004

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    www-sciencedirect-com.proxy.library.vcu.edu/science/article/pii/S2451945621005183
  37. www.nature.com www.nature.com
    Evolution of a histone variant involved in compartmental regulation of NAD metabolism
    1
    1. scibot 15 Dec 2021
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      DOI: 10.1038/s41594-021-00692-5

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    nature.com/articles/s41594-021-00692-5
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
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    1. scibot 11 Dec 2021
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      DOI: 10.1016/j.isci.2021.103442

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633986/
  39. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    1. scibot 10 Dec 2021
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      DOI: 10.1016/j.molcel.2021.11.016

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
  40. www.sciencedirect.com www.sciencedirect.com
    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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      DOI: 10.1016/j.celrep.2021.110080

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    sciencedirect.com/science/article/pii/S2211124721015710
  41. www.sciencedirect.com www.sciencedirect.com
    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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      DOI: 10.1016/j.isci.2021.103503

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    sciencedirect.com/science/article/pii/S2589004221014747
  42. www.sciencedirect.com www.sciencedirect.com
    SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity
    1
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      DOI: 10.1016/j.molcel.2021.11.011

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    sciencedirect.com/science/article/pii/S1097276521009904
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.67952

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    ncbi.nlm.nih.gov/pmc/articles/PMC8626089/
  44. www.sciencedirect.com www.sciencedirect.com
    Ago1 controls myogenic differentiation by regulating eRNA-mediated CBP-guided epigenome reprogramming
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      DOI: 10.1016/j.celrep.2021.110066

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    sciencedirect.com/science/article/pii/S2211124721015527
  45. Nov 2021
  46. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
    1
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      DOI: 10.1016/j.molcel.2021.11.002

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  47. www.sciencedirect.com www.sciencedirect.com
    Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation
    1
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    Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system
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    The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis
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    Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
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    DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse
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    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
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      RRID: AB_302613

      DOI: 10.1016/j.ccell.2018.01.021

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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Species specific differences in use of ANP32 proteins by influenza A virus
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      AB_1791

      DOI: 10.7554/eLife.45066

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  136. www.sciencedirect.com www.sciencedirect.com
    The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation
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      RRID:GR1240576-1

      DOI: 10.1016/j.molcel.2019.10.001

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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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  140. Jun 2021
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    The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis
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    The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair
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    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
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    A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing
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    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
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      DOI: 10.1186/s13072-021-00403-w

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    Correct dosage of X chromosome transcription is controlled by a nuclear pore component
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    XRCC1 prevents toxic PARP1 trapping during DNA base excision repair
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    Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis
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    Boundaries potentiate polycomb response element-mediated silencing
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      DOI: 10.1186/s12915-021-01047-8

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    Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells
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      DOI: 10.1016/j.celrep.2021.109198

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    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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  153. May 2021
  154. www.nature.com www.nature.com
    Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
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      DOI: 10.1038/s41467-021-23205-w

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  155. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein
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      rabbit polyclonal anti-histone H3

      DOI: 10.1002/ijc.33562

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    Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
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    CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones
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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
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    Missense mutations in small muscle protein X-linked ( SMPX ) cause distal myopathy with protein inclusions
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      DOI: 10.1007/s00401-021-02319-x

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    Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication
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    Inhibition of miR-155 potentially protects Lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway
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      DOI: 10.1152/ajpcell.00116.2020

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    Spermiogenic histone transitions and chromatin decondensation in Decapoda
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    Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
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      DOI: 10.1016/j.stem.2020.12.016

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    Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
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    Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
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    Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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    Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
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    A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization
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    A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
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      DOI: 10.1016/j.immuni.2020.10.009

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    Homology-directed repair protects the replicating genome from metabolic assaults
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      DOI: 10.1002/1878-0261.12953

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    Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains
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    H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization
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    STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
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    Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing
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    High-Throughput Discovery and Characterization of Human Transcriptional Effectors
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    Dioctatin Activates ClpP to Degrade Mitochondrial Components and Inhibits Aflatoxin Production
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    Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease
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    Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
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    FANCM regulates repair pathway choice at stalled replication forks
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    Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia
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    Thyroid Hormone-Regulated Expression of Period2 Promotes Liver Urate Production
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    The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming
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    DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
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    MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity
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    Excess histone H3 is a competitive Chk1 inhibitor that controls cell-cycle remodeling in the early Drosophila embryo
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    Deficiency of histone methyltransferase SETD2 in liver leads to abnormal lipid metabolism and hepatocarcinoma
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    Evaluating DNA damage response through immunofluorescence staining of primordial germ cells in Caenorhabditis elegans L1 larva
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells
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    Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution
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  197. Mar 2021
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    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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    HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
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    TRPS1 drives heterochromatic origin refiring and cancer genome evolution
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    CARM1 regulates replication fork speed and stress response by stimulating PARP1
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    Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation
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    Long non-coding RNA00844 inhibits MAPK signaling to suppress the progression of hepatocellular carcinoma by targeting AZGP1
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    Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin
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    Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment
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      DOI: 10.3389/fncel.2020.535549

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    Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis
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    Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1‐dependent mitochondrial fission
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    Serotonin signaling by maternal neurons upon stress ensures progeny survival
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    A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation
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    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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