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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    sciencedirect.com/science/article/pii/S2211124724004443
  3. Apr 2024
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    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    sciencedirect.com/science/article/pii/S2211124724003929
  5. Feb 2024
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    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    sciencedirect.com/science/article/pii/S1097276524000984
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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      DOI: 10.1101/2023.09.27.559698

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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
  10. Jan 2024
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    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    sciencedirect.com/science/article/pii/S1097276523010857
  12. Dec 2023
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    sciencedirect.com/science/article/pii/S2211124723014249
  14. Oct 2023
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    Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability
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      DOI: 10.1016/j.cell.2023.09.008

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    sciencedirect.com/science/article/abs/pii/S0092867423010309
  16. Sep 2023
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    The interplay of TARG1 and PARG protects against genomic instability
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    sciencedirect.com/science/article/pii/S2211124723011245
  18. Aug 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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    1. scibot 26 Aug 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10434289/
  20. 52.53.155.43 52.53.155.43
    crc-23-0268-html.html
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  21. Jul 2023
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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    sciencedirect.com/science/article/pii/S1097276523004720
  23. Jun 2023
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    Detection of endogenous translesion DNA synthesis in single mammalian cells
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    sciencedirect.com/science/article/pii/S2667237523001303
  25. Apr 2023
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    ERCC6L2 mitigates replication stress and promotes centromere stability
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    sciencedirect.com/science/article/pii/S2211124723003406
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
    1
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      DOI: 10.1016/j.isci.2023.106405

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    ncbi.nlm.nih.gov/pmc/articles/PMC10066556/
  28. Mar 2023
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10066556/
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    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723003078
  31. Feb 2023
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    RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1
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    sciencedirect.com/science/article/pii/S2211124723000438
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    GEN1 promotes common fragile site expression
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    sciencedirect.com/science/article/pii/S2211124723000736
  34. Dec 2022
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    The ADP-ribose hydrolase NUDT5 is important for DNA repair
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    sciencedirect.com/science/article/pii/S2211124722017624
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    Quantification of protein enrichment at site-specific DNA double-strand breaks by chromatin immunoprecipitation in cultured human cells
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    sciencedirect.com/science/article/pii/S2666166722007973
  37. Nov 2022
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    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
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    sciencedirect.com/science/article/pii/S2211124722015947
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    Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
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    sciencedirect.com/science/article/pii/S2211124722015443
  40. Aug 2022
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    sciencedirect.com/science/article/pii/S1535610822003257
  42. Jul 2022
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    Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
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    sciencedirect.com/science/article/pii/S2211124722008798
  44. May 2022
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    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
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    sciencedirect.com/science/article/pii/S109727652200394X
  46. Apr 2022
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    sciencedirect.com/science/article/pii/S1097276522002696
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    A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC8971416/
  49. Mar 2022
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    sciencedirect.com/science/article/pii/S2211124722002777
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    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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    sciencedirect.com/science/article/pii/S1097276522000855
  52. Oct 2021
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    RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair
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      DOI: 10.1016/j.celrep.2021.109879

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    sciencedirect.com/science/article/pii/S2211124721013498
  54. Aug 2021
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    Untitled document
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      DOI: 10.1016/j.cell.2018.10.055

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    sciencedirect.com/science/article/pii/S0092867418314545
  56. www.jbc.org www.jbc.org
    Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
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      DOI: 10.1074/jbc.RA118.005231

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    jbc.org/content/294/6/1763.full
  57. Jul 2021
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    The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
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      DOI: 10.1016/j.celrep.2018.08.047

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  59. pubs.acs.org pubs.acs.org
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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      DOI: 10.1021/acsptsci.9b00001

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    pubs.acs.org/doi/full/10.1021/acsptsci.9b00001
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    Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action
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    sciencedirect.com/science/article/pii/S2211124721007816
  61. www.cell.com www.cell.com
    Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
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      DOI: 10.1016/j.molcel.2021.06.011

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      DOI: 10.1016/j.molcel.2021.06.011

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  62. Jun 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
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  64. May 2021
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    Homology-directed repair protects the replicating genome from metabolic assaults
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  66. Mar 2021
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    ER-directed TREX1 limits cGAS activation at micronuclei
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  68. Feb 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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  70. Jan 2021
  71. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
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      DOI: 10.1016/j.celrep.2020.108669

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  72. Dec 2020
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    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
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  74. Oct 2020
  75. www.sciencedirect.com www.sciencedirect.com
    MutSβ Stimulates Holliday Junction Resolution by the SMX Complex
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  76. Sep 2020
  77. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
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      DOI: 10.1016/j.celrep.2020.108179

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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle
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  79. Jan 2020
  80. www.sciencedirect.com www.sciencedirect.com
    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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      DOI: 10.1016/j.chembiol.2019.12.005

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    SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance
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      DOI: 10.1016/j.molcel.2019.07.010

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    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
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    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
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      DOI: 10.1016/j.molcel.2019.10.008

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      RRID:AB_302873

      DOI: 10.1016/j.molcel.2018.11.036

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    Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling
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      RRID:AB_302873

      DOI: 10.1016/j.celrep.2019.05.002

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      DOI: 10.1016/j.molcel.2019.04.024

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      DOI: 10.1016/j.molcel.2019.02.014

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  89. Nov 2018
  90. www.sciencedirect.com www.sciencedirect.com
    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
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    Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
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    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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    sciencedirect.com/science/article/pii/S1535610818300199
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    Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors
    1
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    Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling
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    sciencedirect.com/science/article/pii/S245194561830076X
  97. Nov 2017
  98. www.sciencedirect.com www.sciencedirect.com
    RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
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      Curator: @chewbeccax

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    RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination
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      AB_302873

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1097276517302782
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    RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health
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