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Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The modulation of AUF1 regulates the R-loop resolution activating the immune response in DDR

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1. scibot 06 Jun 2026
  
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  DOI: 10.1016/j.isci.2026.115900
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13196424/
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The heat shock transcription factor, HSF1, stimulates the catalytic engagement of topoisomerase IIβ over topoisomerase IIα

1
1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.molcel.2026.05.014
  
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sciencedirect.com/science/article/pii/S1097276526003205
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression

1
1. scibot 06 Dec 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12676110/
Sep 2025
52.53.155.43 52.53.155.43

2025.09.07.674780v1.full-html.html

1
1. scibot 18 Sep 2025
  
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  AB_303388
  
  DOI: 10.1101/2025.09.07.674780
  
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52.53.155.43/38cf75af3fb71fb2f93a59bfc675836bd9b1fb78/2025.09.07.674780v1.full-html.html
Aug 2025
52.53.155.43 52.53.155.43

lanz-et-al-hdac6-dependent-deacetylation-of-sae2-enhances-sumo1-conjugation-for-mitotic-integrity-html.html

1
1. scibot 27 Aug 2025
  
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  DOI: 10.1038/s44318-025-00532-y
  
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52.53.155.43/6a103bea7fec410145761c98221dd634cac35636/lanz-et-al-hdac6-dependent-deacetylation-of-sae2-enhances-sumo1-conjugation-for-mitotic-integrity-html.html
Mar 2025
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair

1
1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.molcel.2025.02.004
  
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sciencedirect.com/science/article/pii/S1097276525001091
Sep 2024
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Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2018.10.028
  
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sciencedirect.com/science/article/pii/S1097276518308888
Aug 2024
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Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.08.006
  
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sciencedirect.com/science/article/pii/S1097276524006609
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation

1
1. scibot 17 Mar 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-1237
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10940857/
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Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis

2
1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.devcel.2023.12.007
  
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2. scibot 06 Mar 2024
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.devcel.2023.12.007
  
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sciencedirect.com/science/article/pii/S1534580723006573
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma

1
1. scibot 21 Feb 2024
  
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  DOI: 10.1038/s41467-024-45760-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10873513/
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SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability

1
1. scibot 13 Feb 2024
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.celrep.2024.113778
  
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sciencedirect.com/science/article/pii/S2211124724001062
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ATM-inhibitor AZD1390 is a radiosensitizer for breast cancer CNS metastasis

1
1. scibot 03 Nov 2023
  
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  RRID:AB_303388
  
  DOI: 10.1158/1078-0432.CCR-23-0290
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10618650/
Oct 2023
52.53.155.43 52.53.155.43

ccr-23-0290 (1)-html.html

1
1. scibot 07 Oct 2023
  
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  RRID:AB_303388
  
  DOI: 10.1158/1078-0432.ccr-23-0290
  
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52.53.155.43/a77f187501aaa40ccee832d08e4b8e7ab4aac28d/ccr-23-0290-html.html
Sep 2023
52.53.155.43 52.53.155.43

ccr-23-0290 (1)-html.html

1
1. scibot 23 Sep 2023
  
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  RRID:AB_303388
  
  DOI: 10.1158/1078-0432.ccr-23-0290
  
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52.53.155.43/a77f187501aaa40ccee832d08e4b8e7ab4aac28d/ccr-23-0290-html.html
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The interplay of TARG1 and PARG protects against genomic instability

1
1. scibot 12 Sep 2023
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.celrep.2023.113113
  
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sciencedirect.com/science/article/pii/S2211124723011245
Jun 2023
www.embopress.org www.embopress.org

DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres

1
1. scibot 22 Jun 2023
  
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  RRID:AB_303388
  
  DOI: 10.15252/embr.202256492
  
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embopress.org/doi/10.15252/embr.202256492
May 2023
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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

1
1. scibot 20 May 2023
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.cell.2023.04.035
  
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sciencedirect.com/science/article/pii/S0092867423004695
Mar 2023
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Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2

1
1. scibot 02 Mar 2023
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.devcel.2023.02.004
  
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sciencedirect.com/science/article/pii/S1534580723000461
Feb 2023
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GEN1 promotes common fragile site expression

1
1. scibot 02 Feb 2023
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.celrep.2023.112062
  
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sciencedirect.com/science/article/pii/S2211124723000736
Jan 2023
www.cell.com www.cell.com

Loss of epigenetic information as a cause of mammalian aging

1
1. scibot 19 Jan 2023
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.cell.2022.12.027
  
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cell.com/cell/fulltext/S0092-8674(22)01570-7
Oct 2022
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Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks

1
1. scibot 07 Oct 2022
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.molcel.2022.09.012
  
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sciencedirect.com/science/article/pii/S1097276522009017
Aug 2022
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Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases

1
1. scibot 17 Aug 2022
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.cell.2022.06.048
  
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sciencedirect.com/science/article/pii/S0092867422008418
Oct 2021
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NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

1
1. scibot 08 Oct 2021
  
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  AB_303388
  
  DOI: 10.1016/j.molcel.2021.09.016
  
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sciencedirect.com/science/article/pii/S1097276521007504
Aug 2021
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Untitled document

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1. scibot 06 Aug 2021
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.cell.2018.11.039
  
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sciencedirect.com/science/article/pii/S0092867418315642
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

1
1. scibot 17 Jul 2021
  
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  RRID:AB_303388
  
  DOI: 10.7554/eLife.61407
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8279762/
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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

1
1. scibot 09 Jul 2021
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.molcel.2021.06.016
  
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sciencedirect.com/science/article/pii/S1097276521004962
May 2021
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Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

1
1. scibot 21 May 2021
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.molcel.2021.04.028
  
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sciencedirect.com/science/article/pii/S1097276521003579
Mar 2021
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Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions

1
1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108818
  
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sciencedirect.com/science/article/pii/S2211124721001327
Feb 2021
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1
1. scibot 27 Feb 2021
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.cell.2020.11.042
  
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sciencedirect.com/science/article/pii/S0092867420316147
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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

1
1. scibot 24 Feb 2021
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.celrep.2021.108759
  
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  RRID:AB_303388 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721000723
Sep 2020
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Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

1
1. scibot 26 Sep 2020
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.ccell.2019.12.003
  
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  RRID:AB_303388 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819305732
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

1
1. scibot 25 Sep 2020
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.celrep.2020.108166
  
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  RRIDCUR:Validated RRID:AB_303388
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pubmed.ncbi.nlm.nih.gov/32966794/
www.cell.com www.cell.com

PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin

1
1. scibot 17 Sep 2020
  
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  RRID:AB_303388
  
  DOI: 10.1016/j.celrep.2019.12.061
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_303388
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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

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  DOI: 10.1016/j.stem.2020.02.001
  
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cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

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  γH2A.X
  
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METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation

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Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade

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Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma

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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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  DOI: 10.1016/j.immuni.2019.09.013
  
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Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.008
  
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Untitled document

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Nov 2018
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Untitled document

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Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2

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Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

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Regulation of m6A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline

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Nov 2017
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DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro

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Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function

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