477 Matching Annotations
  1. Oct 2024
  2. www.nature.com www.nature.com
    QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
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    1. scibot 01 Oct 2024
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      DOI: 10.1038/s41467-024-52587-w

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    nature.com/articles/s41467-024-52587-w
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    An ILK/STAT3 pathway controls glioblastoma stem cell plasticity
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    1. scibot 27 Sep 2024
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      DOI: 10.1016/j.devcel.2024.09.003

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    sciencedirect.com/science/article/pii/S1534580724005318
  5. www.sciencedirect.com www.sciencedirect.com
    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.molcel.2024.08.037

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    sciencedirect.com/science/article/pii/S1097276524007330
  6. www.sciencedirect.com www.sciencedirect.com
    BBLN-1 is essential for intermediate filament organization and apical membrane morphology
    1
    1. scibot 25 Sep 2024
      RRID:AB_2313768

      DOI: 10.1016/j.cub.2021.03.069

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    sciencedirect.com/science/article/pii/S0960982221004425
  7. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of Stem Cell Activity to Convert Thorns into Branches
    1
    1. scibot 25 Sep 2024
      RRID:AB_2313768

      DOI: 10.1016/j.cub.2020.05.068

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    sciencedirect.com/science/article/pii/S0960982220307557
  8. www.eneuro.org www.eneuro.org
    Differences in GluN2B-containing NMDA receptors result in distinct long-term plasticity at ipsilateral vs. contralateral cortico-striatal synapses
    1
    1. scibot 25 Sep 2024
      RRID:AB_2313768

      DOI: 10.1523/ENEURO.0118-19.2019

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    eneuro.org/content/6/6/ENEURO.0118-19.2019
  9. www.sciencedirect.com www.sciencedirect.com
    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.molcel.2019.10.026

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    sciencedirect.com/science/article/pii/S1097276519308044
  10. www.sciencedirect.com www.sciencedirect.com
    Functional Metabolomics Describes the Yeast Biosynthetic Regulome
    1
    1. scibot 25 Sep 2024
      AB_2313768

      DOI: 10.1016/j.cell.2016.09.007

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    sciencedirect.com/science/article/pii/S0092867416312375
  11. www.cell.com www.cell.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
    1
    1. scibot 12 Sep 2024
      AB_303395

      DOI: 10.1016/j.cell.2024.08.020

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    cell.com/cell/fulltext/S0092-8674(24)00911-5
  12. www.sciencedirect.com www.sciencedirect.com
    A compact, versatile drug-induced splicing switch system with minimal background expression
    1
    1. scibot 05 Sep 2024
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      DOI: 10.1016/j.crmeth.2024.100842

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    sciencedirect.com/science/article/pii/S2667237524002157
  13. www.sciencedirect.com www.sciencedirect.com
    PICKLE-mediated nucleosome condensing drives H3K27me3 spreading for the inheritance of Polycomb memory during differentiation
    1
    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S1097276524006920
  14. Aug 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Changes in the bile acid pool and timing of female puberty: potential novel role of hypothalamic TGR5
    1
    1. scibot 23 Aug 2024
      RRID:AB_303395

      DOI: 10.1210/endocr/bqae098

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    ncbi.nlm.nih.gov/pmc/articles/PMC11334072/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
    1
    1. scibot 21 Aug 2024
      AB_303395

      DOI: 10.1016/j.molcel.2024.07.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
  17. www.sciencedirect.com www.sciencedirect.com
    VAP-mediated membrane-tethering mechanisms implicate ER-PM contact function in pH homeostasis
    1
    1. scibot 19 Aug 2024
      RRID:AB_303395

      DOI: 10.1016/j.celrep.2024.114592

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    sciencedirect.com/science/article/pii/S2211124724009215
  18. www.biorxiv.org www.biorxiv.org
    Spontaneous activity of striatal projection neurons supports maturation of striatal inputs to substantia nigra dopaminergic neurons
    1
    1. scibot 13 Aug 2024
      ab290, Abcam

      DOI: 10.1101/2024.01.05.574371

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    biorxiv.org/content/10.1101/2024.01.05.574371v2
  19. www.cell.com www.cell.com
    Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1016/j.cub.2021.02.043

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    cell.com/current-biology/fulltext/S0960-9822(21)00287-6
  20. www.embopress.org www.embopress.org
    The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder
    1
    1. scibot 02 Aug 2024
      ab290

      DOI: 10.15252/embr.202051991

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    embopress.org/doi/full/10.15252/embr.202051991
  21. Jul 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
    1
    1. scibot 31 Jul 2024
      AB_303395

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    sciencedirect.com/science/article/pii/S1550413124002766
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PFTAIRE Kinase L63 Interactor 1A (Pif1A Protein) Is Required for Actin Cone Movement during Spermatid Individualization in Drosophila melanogaster
    1
    1. scibot 27 Jul 2024
      AB_303395

      DOI: 10.3390/ijms23063011

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    ncbi.nlm.nih.gov/pmc/articles/PMC8950383/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CPF-like phosphatase module links transcription termination to chromatin silencing
    1
    1. scibot 26 Jul 2024
      RRID:AB_303395

      DOI: 10.1016/j.molcel.2024.05.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC7616277/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons
    1
    1. scibot 20 Jul 2024
      RRID:AB_303395

      DOI: 10.1016/j.celrep.2020.107654

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    ncbi.nlm.nih.gov/pmc/articles/PMC7306179/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila
    1
    1. scibot 18 Jul 2024
      RRID:AB_303395

      DOI: 10.1186/s40478-020-01028-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC7487709/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2020.107695

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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER–mitochondrial junctions
    1
    1. scibot 14 Jul 2024
      RRID:AB_303395

      DOI: 10.1242/jcs.261728

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    ncbi.nlm.nih.gov/pmc/articles/PMC11234384/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila
    1
    1. scibot 14 Jul 2024
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      DOI: 10.1186/s13041-023-01026-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10186683/
  30. www.sciencedirect.com www.sciencedirect.com
    Polymerization of ZBTB transcription factors regulates chromatin occupancy
    1
    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.molcel.2024.06.010

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    sciencedirect.com/science/article/pii/S1097276524005136
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pioneer transcription factor Zelda facilitates the exit from regeneration and restoration of patterning in Drosophila
    1
    1. scibot 06 Jul 2024
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      DOI: 10.1101/2024.05.30.596672

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    ncbi.nlm.nih.gov/pmc/articles/PMC11160785/
  32. Jun 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Paradoxical activation of c-Src as a drug-resistant mechanism
    2
    1. scibot 28 Jun 2024
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      DOI: 10.1016/j.celrep.2021.108876

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      RRID:AB_303395

      DOI: 10.1016/j.celrep.2021.108876

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    sciencedirect.com/science/article/pii/S221112472100190X
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell-autonomous role of leucine-rich repeat kinase in the protection of dopaminergic neuron survival
    1
    1. scibot 13 Jun 2024
      RRID:AB_303395

      DOI: 10.7554/eLife.92673

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    ncbi.nlm.nih.gov/pmc/articles/PMC11164531/
  35. www.sciencedirect.com www.sciencedirect.com
    The browning and mobilization of subcutaneous white adipose tissue supports efficient skin repair
    1
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      Abcamab290

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    sciencedirect.com/science/article/pii/S1550413124001815
  36. May 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.devcel.2024.05.005

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    sciencedirect.com/science/article/pii/S1534580724003228
  38. www.sciencedirect.com www.sciencedirect.com
    TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.celrep.2024.114294

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    sciencedirect.com/science/article/pii/S2211124724006223
  39. www.cell.com www.cell.com
    Trio preserves motor synapses and prolongs motor ability during aging
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.celrep.2024.114256

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    cell.com/cell-reports/fulltext/S2211-1247(24)00584-9
  40. www.sciencedirect.com www.sciencedirect.com
    Peptide REF1 is a local wound signal promoting plant regeneration
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      DOI: 10.1016/j.cell.2024.04.040

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    sciencedirect.com/science/article/pii/S0092867424004665
  41. www.sciencedirect.com www.sciencedirect.com
    TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
    1
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      DOI: 10.1016/j.celrep.2024.114214

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    sciencedirect.com/science/article/pii/S2211124724005424
  42. www.sciencedirect.com www.sciencedirect.com
    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
    1
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      RRID:AB_303395

      DOI: 10.1016/j.ebiom.2024.105124

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    sciencedirect.com/science/article/pii/S2352396424001592
  43. elifesciences.org elifesciences.org
    Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival
    1
    1. scibot 03 May 2024
      RRID:AB_303395

      DOI: 10.7554/eLife.92673.3

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    elifesciences.org/reviewed-preprints/92673
  44. www.sciencedirect.com www.sciencedirect.com
    MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
    1
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      DOI: 10.1016/j.neuron.2024.04.007

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    sciencedirect.com/science/article/pii/S0896627324002459
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats with α-synucleinopathy
    1
    1. scibot 01 May 2024
      RRID:AB_303395

      DOI: 10.4103/1673-5374.391190

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    ncbi.nlm.nih.gov/pmc/articles/PMC11040301/
  46. Apr 2024
  47. www.sciencedirect.com www.sciencedirect.com
    A critical suppression feedback loop determines soybean photoperiod sensitivity
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  65. Feb 2024
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    EHBP1 is critically involved in dendritic arbor formation and is coupled to factors promoting actin filament formation
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    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    The BAS chromatin remodeler determines brassinosteroid-induced transcriptional activation and plant growth in Arabidopsis
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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    Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age
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    Fat- and sugar-induced signals regulate sweet and fat taste perception in Drosophila
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    MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice
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    Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival
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    The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A
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    Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity
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    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
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    Ubiquitination of the protocadherin-γA3 variable cytoplasmic domain modulates cell-cell interaction
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    The interplay of TARG1 and PARG protects against genomic instability
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    Ethylene produced in carpel primordia controls CmHB40 expression to inhibit stamen development
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    RhoB Promotes Salmonella survival by Regulating Autophagy
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    Developing a peptide to disrupt cohesin head domain interactions
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    End-binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of dense core vesicles
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    Phosphatidylinositol 3-phosphate regulates iron transport via PI3P-binding CgPil1 protein
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    Microglial Nogo delays recovery following traumatic brain injury in mice
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    The OsbHLH002/OsICE1-OSH1 module orchestrates secondary cell wall formation in rice
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    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis
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    Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
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    Protocol for biallelic tagging of an endogenous gene using CRISPR-Cas9 in human cells
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    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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    Ubiquitin-independent proteasomal degradation driven by C-degron pathways
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    Divergent expression of paralogous genes by modification of shared enhancer activity through a promoter-proximal silencer
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  130. Apr 2023
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    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    Boosting BDNF in muscle rescues impaired in vivo axonal transport in a mouse model of DI-CMTC peripheral neuropathy
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H3 phospho-regulation by KimH3 in both interphase and mitosis
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  135. Mar 2023
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    ROLE OF THE MITOCHONDRIAL PERMEABILITY TRANSITION IN BONE METABOLISM AND AGING
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway
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    Drosophila transition fibers are essential for IFT-dependent ciliary elongation but not basal body docking and ciliary budding
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    Nitrate availability controls translocation of the transcription factor NAC075 for cell-type-specific reprogramming of root growth
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    Oscillating field stimulation promotes neurogenesis of neural stem cells through miR-124/Tal1 axis to repair spinal cord injury in rats
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    The Arabidopsis TIR-NBS-LRR protein CSA1 guards BAK1-BIR3 homeostasis and mediates convergence of pattern- and effector-induced immune responses
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    A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
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    Topoisomerases I and II facilitate condensin DC translocation to organize and repress X chromosomes in C. elegans
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    De novo establishment of circuit modules restores locomotion after spinal cord injury in adult zebrafish
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    Chromatin remodeling is required for sRNA-guided DNA elimination in Paramecium
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  165. Sep 2022
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    Protocol to use RNaseH1-based CRISPR to modulate locus-associated R-loops
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    Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity
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    Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
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    Mechanical conflict caused by a cell-wall-loosening enzyme activates de novo shoot regeneration
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    Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy
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    The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
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    POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function
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    Protein disulfide isomerase modulation of TRPV1 controls heat hyperalgesia in chronic pain
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    Exploiting flow cytometry for the unbiased quantification of protein inclusions in Caenorhabditis elegans
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  190. academic.oup.com academic.oup.com
    SKIP Regulates ABA Signaling Through Alternative Splicing in Arabidopsis
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      DOI: 10.1093/pcp/pcac014

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  191. Mar 2022
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    A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise
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      DOI: 10.1016/j.stem.2022.02.008

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  193. Feb 2022
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    A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells
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    LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
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      DOI: 10.15252/embj.2021108119

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    Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage
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    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
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    Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
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    RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair
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    Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
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  201. Jan 2022
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    WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
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    Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
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    NHR-80 senses the mitochondrial UPR to rewire citrate metabolism for lipid accumulation in Caenorhabditis elegans
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    Identification and functional characterization of transcriptional activators in human cells
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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  207. Dec 2021
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    NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis
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    A brain-to-spinal sensorimotor loop for repetitive self-grooming
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    SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
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  211. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells
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      DOI: 10.1002/cne.25272

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    Suppression of MYC transcription activators by the immune cofactor NPR1 fine-tunes plant immune responses
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silencing long ascending propriospinal neurons after spinal cord injury improves hindlimb stepping in the adult rat
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      DOI: 10.7554/eLife.70058

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639151/
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    Closantel is an allosteric inhibitor of human Taspase1
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    CAR-T cells Targeting TSHR Demonstrate Safety and Potent Preclinical Activity Against Differentiated Thyroid Cancer
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      DOI: 10.1210/clinem/dgab819

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab819/6423845
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal and distal spinal neurons innervating multiple synergist and antagonist motor pools
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      DOI: 10.7554/eLife.70858

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631798/
  218. Nov 2021
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    Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
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    Arabidopsis ATXR2 represses de novo shoot organogenesis in the transition from callus to shoot formation
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    Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
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      DOI: 10.1523/JNEUROSCI.1914-20.2021

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    A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
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    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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  225. Oct 2021
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    Turnover of fear engram cells by repeated experience
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    DREAM represses distinct targets by cooperating with different THAP domain proteins
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    A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle
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    Body-fat sensor triggers ribosome maturation in the steroidogenic gland to initiate sexual maturation in Drosophila
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    SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
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      DOI: 10.1016/j.cub.2021.09.022

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