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33 Matching Annotations

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Glioblastoma stem cell growth requires DOT1L-MED23 control of enhancer accessibility

1
1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117647
  
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sciencedirect.com/science/article/pii/S2211124726007254
Aug 2024
www.cell.com www.cell.com

DOT1L/H3K79me2 represses HIV-1 reactivation via recruiting DCAF1

1
1. scibot 13 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114368
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00696-X
Nov 2023
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RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size

1
1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.cell.2023.10.012
  
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sciencedirect.com/science/article/pii/S0092867423011285
Jun 2023
www.embopress.org www.embopress.org

DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres

1
1. scibot 22 Jun 2023
  
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  RRID:AB_303937
  
  DOI: 10.15252/embr.202256492
  
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embopress.org/doi/10.15252/embr.202256492
Dec 2022
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SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia

1
1. scibot 01 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111727
  
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sciencedirect.com/science/article/pii/S2211124722016059
Jun 2022
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Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells

1
1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.chembiol.2022.05.006
  
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sciencedirect.com/science/article/pii/S2451945622001982
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Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

1
1. scibot 18 Jun 2022
  
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  DOI: 10.1016/j.molcel.2022.05.023
  
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sciencedirect.com/science/article/pii/S1097276522004907
Feb 2022
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Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

2
1. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.stem.2022.01.010
  
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2. scibot 11 Feb 2022
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.stem.2022.01.010
  
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sciencedirect.com/science/article/pii/S1934590922000108
Nov 2021
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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

1
1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110044
  
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sciencedirect.com/science/article/pii/S2211124721015308
Sep 2021
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DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation

1
1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109739
  
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sciencedirect.com/science/article/pii/S221112472101192X
Aug 2021
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Untitled document

1
1. scibot 13 Aug 2021
  
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  DOI: 10.1016/j.celrep.2019.03.047
  
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sciencedirect.com/science/article/pii/S2211124719303638
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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

1
1. scibot 04 Aug 2021
  
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  DOI: 10.1016/j.ccell.2018.10.014
  
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sciencedirect.com/science/article/pii/S153561081830480X
Jul 2021
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Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

1
1. scibot 22 Jul 2021
  
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  AB_303937
  
  DOI: 10.1016/j.celrep.2021.109410
  
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sciencedirect.com/science/article/pii/S2211124721008238
Apr 2021
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Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia

1
1. scibot 17 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.05.014
  
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  RRID:AB_303937 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820302646
Dec 2020
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The Methyltransferase DOT1L Controls Activation and Lineage Integrity in CD4+ T Cells during Infection and Inflammation

1
1. scibot 17 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108505
  
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sciencedirect.com/science/article/pii/S2211124720314947
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The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses

1
1. scibot 17 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108504
  
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sciencedirect.com/science/article/pii/S2211124720314935
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes

1
1. scibot 22 Nov 2020
  
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  RRID:AB_303937
  
  DOI: 10.7554/eLife.59990
  
  Resource: (Abcam Cat# ab3594, RRID:AB_303937)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_303937
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ncbi.nlm.nih.gov/pmc/articles/PMC7661038/
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory

1
1. scibot 03 Nov 2020
  
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  AB_303937
  
  DOI: 10.1016/j.molcel.2020.10.005
  
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pubmed.ncbi.nlm.nih.gov/33108759/
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma

1
1. scibot 27 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108293
  
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pubmed.ncbi.nlm.nih.gov/33086062/
Sep 2020
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Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

1
1. scibot 17 Sep 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.molcel.2020.03.010
  
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  RRID:AB_303937 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276520301581
Jan 2020
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HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

1
1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.ccell.2019.10.011
  
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sciencedirect.com/science/article/pii/S1535610819304854
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MeCP2 Represses the Rate of Transcriptional Initiation of Highly Methylated Long Genes

1
1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.molcel.2019.10.032
  
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sciencedirect.com/science/article/pii/S109727651930810X
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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

1
1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.ccell.2019.11.001
  
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sciencedirect.com/science/article/pii/S1535610819305215
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.molcel.2019.03.029
  
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sciencedirect.com/science/article/pii/S1097276519302333
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.celrep.2018.12.083
  
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sciencedirect.com/science/article/pii/S2211124718320436
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Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome

1
1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.molcel.2018.10.028
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1097276518308888
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_303937
  
  DOI: 10.1016/j.molcel.2019.01.012
  
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sciencedirect.com/science/article/pii/S1097276519300127
Nov 2018
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Cohesin Loss Eliminates All Loop Domains

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417311200
Nov 2017
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Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase

1
1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0092867417308772
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Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

1
1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1097276517305075
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A Metabolic Function for Phospholipid and Histone Methylation

1
1. scibot 08 Nov 2017
  
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  AB_303937
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1097276517301636
elifesciences.org elifesciences.org

Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

1
1. scibot 08 Nov 2017
  
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  Mouse monoclonal anti -H3K79me2
  
  Curator: @jcabotaj
  
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elifesciences.org/content/4/e07420