Hypothesis

26 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer

1
1. scibot 01 Nov 2025
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.xcrm.2025.102429
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125005026
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development of a First-in-Class Click Chemistry–Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial

1
1. scibot 07 Sep 2025
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1158/1078-0432.CCR-24-2539
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12402790/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combined KRAS inhibition and immune therapy generates durable complete responses in an autochthonous PDAC model

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1158/2159-8290.CD-24-0489
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11858029/
Mar 2025
link.springer.com link.springer.com

PRMT3 drives PD-L1-mediated immune escape through activating PDHK1-regulated glycolysis in hepatocellular carcinoma

1
1. scibot 11 Mar 2025
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1038/s41419-025-07482-7
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

link.springer.com/article/10.1038/s41419-025-07482-7
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1126/scitranslmed.adj9366
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
May 2024
www.sciencedirect.com www.sciencedirect.com

Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity

1
1. scibot 14 May 2024
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.immuni.2024.04.018
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761324002231
Apr 2024
aacrjournals.org aacrjournals.org

Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis

1
1. scibot 19 Apr 2024
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1158/0008-5472.CAN-23-1542
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lethal severe fever with thrombocytopenia syndrome virus infection causes systemic germinal centre failure and massive T cell apoptosis in cats

1
1. scibot 23 Jan 2024
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.3389/fmicb.2023.1333946
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10796997/
www.mdpi.com www.mdpi.com

The Interaction of HMGB1 with the Proinflammatory TREM-1 Receptor Generates Cytotoxic Lymphocytes Active against HLA-Negative Tumor Cells

1
1. scibot 11 Jan 2024
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.3390/ijms25010627
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

mdpi.com/1422-0067/25/1/627
Nov 2023
www.sciencedirect.com www.sciencedirect.com

TIGIT contributes to the regulation of 4-1BB and does not define NK cell dysfunction in glioblastoma

1
1. scibot 29 Nov 2023
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.isci.2023.108353
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223024306
Oct 2023
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model

1
1. scibot 20 Oct 2023
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1096/fj.202202036R
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202036R
Jun 2023
aacrjournals.org aacrjournals.org

EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression

1
1. scibot 10 Jun 2023
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1158/2326-6066.CIR-22-0374
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

aacrjournals.org/cancerimmunolres/article/11/6/830/726521/EBV-Upregulated-B7-H3-Inhibits-NK-cell-Mediated
May 2023
www.nature.com www.nature.com

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

1
1. scibot 20 May 2023
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1038/s41467-023-38605-3
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

nature.com/articles/s41467-023-38605-3
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Spatial heterogeneity of infiltrating T cells in high-grade serous ovarian cancer revealed by multi-omics analysis

1
1. scibot 24 Dec 2022
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.xcrm.2022.100856
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379122004207
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Impacts of neoadjuvant chemoradiotherapy on the immune landscape of esophageal squamous cell carcinoma

1
1. scibot 24 Nov 2022
  
  in Public
  
  AB_304251
  
  DOI: 10.1016/j.ebiom.2022.104371
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396422005539
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development

2
1. scibot 11 Feb 2022
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.isci.2022.103790
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
2. scibot 11 Feb 2022
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.isci.2022.103790
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222000608
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

1
1. scibot 16 Aug 2021
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.cell.2021.07.020
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867421008795
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hsp70 Interacts with the TREM-1 Receptor Expressed on Monocytes and Thereby Stimulates Generation of Cytotoxic Lymphocytes Active against MHC-Negative Tumor Cells

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.3390/ijms22136889
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8267615/
May 2021
www.sciencedirect.com www.sciencedirect.com

Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.molcel.2020.10.015
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727652030722X
www.sciencedirect.com www.sciencedirect.com

CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance

1
1. scibot 04 May 2021
  
  in Public
  
  RRID:AB_304251
  
  DOI: 10.1016/j.stem.2021.04.011
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590921001685
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

1
1. scibot 04 Sep 2020
  
  in Public
  
  Rabbit anti-mouse Granzyme B
  
  DOI: 10.1016/j.cell.2020.02.015
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_304251

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867420301598
www.sciencedirect.com www.sciencedirect.com

ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

1
1. scibot 03 Sep 2020
  
  in Public
  
  Granzyme B Rabbit mAb
  
  DOI: 10.1016/j.ccell.2020.02.006
  
  Resource: (Abcam Cat# ab4059, RRID:AB_304251)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_304251
  
  What is this?
  
  RRID:AB_304251 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_304251

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820300957
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_304251
  
  Resource used:
  
  (Abcam Cat# ab4059, RRID:AB_304251)
  
  SciCrunch record: RRID:AB_304251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_304251
Visit annotations in context

Tags

RRID:AB_304251

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6075866/
www.sciencedirect.com www.sciencedirect.com

Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_304251
  
  Curator: @evieth
  
  Resource used:
  
  (Abcam Cat# ab4059, RRID:AB_304251)
  
  SciCrunch record: RRID:AB_304251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_304251 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2372770518300019
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_304251
  
  Curator: @Jmenke
  
  Resource used:
  
  (Abcam Cat# ab4059, RRID:AB_304251)
  
  SciCrunch record: RRID:AB_304251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_304251 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_304251

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610817302982