76 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
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    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00240-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
    1
    1. scibot 05 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  5. Jul 2024
  6. www.cell.com www.cell.com
    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
    1
    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.crmeth.2024.100814

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    cell.com/cell-reports-methods/fulltext/S2667-2375(24)00179-6
  7. Jun 2024
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A comparative analysis of paxillin and Hic-5 proximity interactomes
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1002/cm.21878

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    onlinelibrary.wiley.com/doi/10.1002/cm.21878
  9. May 2024
  10. 52.53.155.43 52.53.155.43
    Centriolar satellites are sites of translation of centrosomal and ciliary proteins
    1
    1. scibot 16 May 2024
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      DOI: 10.1101/2024.02.22.581531

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    52.53.155.43/b4facf67b457be9515b769549e8e513b0c45add0/2024.02.22.581531v1.full-html.html
  11. Apr 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
    1
    1. scibot 20 Apr 2024
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      DOI: 10.1016/j.ebiom.2024.105129

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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Golgi checkpoint: Golgi unlinking during G2 is necessary for spindle formation and cytokinesis
    1
    1. scibot 19 Mar 2024
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      DOI: 10.26508/lsa.202302469

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    ncbi.nlm.nih.gov/pmc/articles/PMC10941482/
  15. www.sciencedirect.com www.sciencedirect.com
    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
    1
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.bbadis.2024.167116

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    sciencedirect.com/science/article/pii/S0925443924001054
  16. Feb 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Kin17 regulates proper cortical localization of Miranda in Drosophila neuroblasts by regulating Flfl expression
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113823

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    sciencedirect.com/science/article/pii/S2211124724001517
  18. www.sciencedirect.com www.sciencedirect.com
    3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.celrep.2023.113554

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    sciencedirect.com/science/article/pii/S2211124723015668
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Nanoscale organization of the endogenous ASC speck
    1
    1. scibot 29 Nov 2023
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      DOI: 10.1016/j.isci.2023.108382

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    sciencedirect.com/science/article/pii/S2589004223024598
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells
    2
    1. scibot 11 Nov 2023
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      DOI: 10.7554/eLife.83157

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      DOI: 10.7554/eLife.83157

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629821/
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.devcel.2023.10.003

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    sciencedirect.com/science/article/pii/S1534580723005233
  24. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.devcel.2023.09.008

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    sciencedirect.com/science/article/pii/S1534580723004951
  25. Jul 2023
  26. www.embopress.org www.embopress.org
    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
    1
    1. scibot 08 Jul 2023
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      DOI: 10.15252/embj.2022112812

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    embopress.org/doi/full/10.15252/embj.2022112812
  27. Jun 2023
  28. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1038/s41467-023-39241-7

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    nature.com/articles/s41467-023-39241-7
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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    1. scibot 18 May 2023
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      DOI: 10.1016/j.celrep.2023.112531

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    sciencedirect.com/science/article/pii/S2211124723005429
  31. www.sciencedirect.com www.sciencedirect.com
    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.isci.2023.106652

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    sciencedirect.com/science/article/pii/S2589004223007290
  32. Mar 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
    1
    1. scibot 16 Mar 2023
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      DOI: 10.3389/fimmu.2023.1060905

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    ncbi.nlm.nih.gov/pmc/articles/PMC9992642/
  34. Feb 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates
    1
    1. scibot 24 Feb 2023
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      DOI: 10.7554/eLife.34959

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    ncbi.nlm.nih.gov/pmc/articles/PMC5976437/
  36. www.sciencedirect.com www.sciencedirect.com
    Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112104

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    sciencedirect.com/science/article/pii/S2211124723001158
  37. www.sciencedirect.com www.sciencedirect.com
    Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain
    1
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      DOI: 10.1016/j.neuron.2023.01.020

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    sciencedirect.com/science/article/pii/S0896627323000703
  38. www.sciencedirect.com www.sciencedirect.com
    Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1016/j.cub.2023.01.010

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    sciencedirect.com/science/article/pii/S0960982223000106
  39. Jan 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development
    1
    1. scibot 22 Jan 2023
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      DOI: 10.7554/eLife.78202

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    ncbi.nlm.nih.gov/pmc/articles/PMC9851619/
  41. www.sciencedirect.com www.sciencedirect.com
    Protocol to measure centrosome cohesion deficits mediated by pathogenic LRRK2 in cultured cells using confocal microscopy
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.xpro.2022.102024

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    sciencedirect.com/science/article/pii/S2666166722009042
  42. www.sciencedirect.com www.sciencedirect.com
    Expansion microscopy of the chick embryo neural tube to overcome molecular crowding at the centrosomes-cilia
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.xpro.2022.101997

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    sciencedirect.com/science/article/pii/S2666166722008772
  43. Nov 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
    1
    1. scibot 18 Nov 2022
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      DOI: 10.7554/eLife.81606

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    ncbi.nlm.nih.gov/pmc/articles/PMC9651953/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pericentriolar matrix (PCM) integrity relies on cenexin and polo-like kinase (PLK)1
    1
    1. scibot 04 Nov 2022
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      DOI: 10.1091/mbc.E22-01-0015

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    ncbi.nlm.nih.gov/pmc/articles/PMC9582643/
  46. www.sciencedirect.com www.sciencedirect.com
    A high-throughput electron tomography workflow reveals over-elongated centrioles in relapsed/refractory multiple myeloma
    1
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      DOI: 10.1016/j.crmeth.2022.100322

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    sciencedirect.com/science/article/pii/S2667237522002120
  47. Jul 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
    1
    1. scibot 27 Jul 2022
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      DOI: 10.7554/eLife.77892

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    ncbi.nlm.nih.gov/pmc/articles/PMC9307276/
  49. Jun 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
    1
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      DOI: 10.1016/j.isci.2022.104476

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    sciencedirect.com/science/article/pii/S2589004222007477
  51. Apr 2022
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Distribution of prototypical primary cilia markers in subtypes of retinal ganglion cells
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    1. scibot 20 Apr 2022
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      DOI: 10.1002/cne.25326

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    onlinelibrary.wiley.com/doi/10.1002/cne.25326
  53. Jan 2022
  54. journals.sagepub.com journals.sagepub.com
    Carboxypeptidase E Independently Changes Microtubule Glutamylation, Dendritic Branching, and Neuronal Migration
    2
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      DOI: 10.1177/17590914211062765

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      DOI: 10.1177/17590914211062765

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    journals.sagepub.com/doi/full/10.1177/17590914211062765
  55. Oct 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles
    1
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      DOI: 10.1074/jbc.RA120.014791

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    ncbi.nlm.nih.gov/pmc/articles/PMC7535905/
  57. Aug 2021
  58. www.sciencedirect.com www.sciencedirect.com
    A light-switching pyrene probe to detect phase separated biomolecules
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      DOI: 10.1016/j.isci.2021.102865

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    sciencedirect.com/science/article/pii/S2589004221008336
  59. Jul 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1016/j.cub.2019.07.061

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    sciencedirect.com/science/article/pii/S0960982219309418
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 28 Jul 2021
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      DOI: 10.7554/eLife.24578

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    ncbi.nlm.nih.gov/pmc/articles/PMC5576923/
  62. rupress.org rupress.org
    TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity
    1
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      DOI: 10.1083/jcb.202010180

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    rupress.org/jcb/article/220/7/e202010180/212098/TRIM37-prevents-formation-of-condensate-organized
  63. Jun 2021
  64. www.nature.com www.nature.com
    The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
    1
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      DOI: 10.1038/s41467-021-23550-w

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  65. May 2021
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    14–3-3γ prevents centrosome duplication by inhibiting NPM1 function
    1
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      pericentrin

      DOI: 10.1111/gtc.12848

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  67. www.sciencedirect.com www.sciencedirect.com
    Multimerization of Zika Virus-NS5 Causes Ciliopathy and Forces Premature Neurogenesis
    1
    1. scibot 09 May 2021
      AB_304461

      DOI: 10.1016/j.stem.2020.10.002

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  68. www.sciencedirect.com www.sciencedirect.com
    RAB19 Directs Cortical Remodeling and Membrane Growth for Primary Ciliogenesis
    1
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      RRID:AB_304461

      DOI: 10.1016/j.devcel.2020.12.003

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  69. www.sciencedirect.com www.sciencedirect.com
    Acto-myosin network geometry defines centrosome position
    1
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      RRID:AB_304461

      DOI: 10.1016/j.cub.2021.01.002

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  70. Apr 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells
    1
    1. scibot 30 Apr 2021
      RRID:AB_304461

      DOI: 10.1016/j.cmet.2020.10.025

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  72. Feb 2021
  73. www.pnas.org www.pnas.org
    E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
    1
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      rabbit anti-pericentrin

      DOI: 10.1073/pnas.2015794118

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  74. Dec 2020
  75. www.cell.com www.cell.com
    The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability
    1
    1. scibot 10 Dec 2020
      RRID:AB_304461

      DOI: 10.1016/j.cub.2020.10.096

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    cell.com/current-biology/abstract/S0960-9822(20)31673-0
  76. Nov 2020
  77. www.sciencedirect.com www.sciencedirect.com
    De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment
    1
    1. scibot 20 Nov 2020
      rabbit polyclonal anti-pericentrin

      DOI: 10.1016/j.ajhg.2020.10.012

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    sciencedirect.com/science/article/pii/S0002929720303700
  78. Sep 2020
  79. www.sciencedirect.com www.sciencedirect.com
    A Genetic Toggle for Chemical Control of Individual Plk1 Substrates
    1
    1. scibot 26 Sep 2020
      RRID:AB_304461

      DOI: 10.1016/j.chembiol.2020.01.007

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  80. www.sciencedirect.com www.sciencedirect.com
    A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance
    1
    1. scibot 16 Sep 2020
      RRID:AB_304461

      DOI: 10.1016/j.celrep.2020.02.079

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  81. www.sciencedirect.com www.sciencedirect.com
    Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit
    1
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      AB_304461

      DOI: 10.1016/j.stem.2020.01.018

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  82. www.nature.com www.nature.com
    Centrosome anchoring regulates progenitor properties and cortical formation
    1
    1. scibot 05 Sep 2020
      RRID:AB_304461

      DOI: 10.1038/s41586-020-2139-6

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  83. mcr.aacrjournals.org mcr.aacrjournals.org
    Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects
    1
    1. scibot 03 Sep 2020
      rabbit anti-pericentrin

      DOI: 10.1158/1541-7786.MCR-19-1122

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  84. Jan 2020
  85. www.sciencedirect.com www.sciencedirect.com
    Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development
    1
    1. scibot 13 Jan 2020
      RRID:AB_304461

      DOI: 10.1016/j.cub.2019.07.061

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  86. www.sciencedirect.com www.sciencedirect.com
    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
    1
    1. scibot 13 Jan 2020
      AB_304461

      DOI: 10.1016/j.cels.2019.05.009

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    sciencedirect.com/science/article/pii/S2405471219301905
  87. link.springer.com link.springer.com
    CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment
    1
    1. scibot 13 Jan 2020
      RRID:AB_304461

      DOI: 10.1186/s12915-019-0694-9

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  88. www.sciencedirect.com www.sciencedirect.com
    The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype
    1
    1. scibot 13 Jan 2020
      RRID:AB_304461

      DOI: 10.1016/j.chembiol.2018.11.014

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    sciencedirect.com/science/article/pii/S2451945618304367
  89. Nov 2018
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints
    1
    1. scibot 05 Nov 2018
      antibody directed towards pericentrin

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    ncbi.nlm.nih.gov/pmc/articles/PMC3635462/
  91. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
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      RRID:AB_304461

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    sciencedirect.com/science/article/pii/S2211124718312208
  92. www.sciencedirect.com www.sciencedirect.com
    Trisomy 21 Represses Cilia Formation and Function
    1
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      RRID:AB_304461

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    sciencedirect.com/science/article/pii/S1534580718305938
  93. www.sciencedirect.com www.sciencedirect.com
    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
    1
    1. scibot 05 Nov 2018
      RRID: AB_304461

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    sciencedirect.com/science/article/pii/S0960982217315282
  94. elifesciences.org elifesciences.org
    Untitled document
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      RRID:AB_304461

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    elifesciences.org/articles/34959
  95. www.sciencedirect.com www.sciencedirect.com
    Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens
    1
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      AB_304461

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    sciencedirect.com/science/article/pii/S240547121830187X
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Acute and Rapid Degradation of Endogenous Proteins
    2
    1. scibot 05 Nov 2018
      RRID:AB_304461

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      RRID:AB_304461

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    ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
  97. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps
    1
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      AB_304461

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    sciencedirect.com/science/article/pii/S1534580717308262
  98. Nov 2017
  99. www.sciencedirect.com www.sciencedirect.com
    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
    1
    1. scibot 09 Nov 2017
      AB_304461

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0960982217307236
  100. www.sciencedirect.com www.sciencedirect.com
    Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells
    1
    1. scibot 08 Nov 2017
      RRID:AB_304461

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    sciencedirect.com/science/article/pii/S0960982217310692
  101. elifesciences.org elifesciences.org
    PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex
    1
    1. scibot 08 Nov 2017
      RRID:AB_304461

      Curator: @kaitlinsung

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    elifesciences.org/articles/24578
  102. www.sciencedirect.com www.sciencedirect.com
    Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals
    1
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      AB_304461

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  103. www.sciencedirect.com www.sciencedirect.com
    A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers
    1
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      AB_304461

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  104. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
    1
    1. scibot 08 Nov 2017
      AB_304461

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    sciencedirect.com/science/article/pii/S0092867417305858
  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria
    1
    1. scibot 08 Nov 2017
      AB_304461

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    onlinelibrary.wiley.com/doi/10.1002/jcp.25839/full
  106. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing
    2
    1. scibot 08 Nov 2017
      AB_304461

      Curator: @gabimpine

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    2. scibot 08 Nov 2017
      AB_304461

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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0292-z