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    AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer
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    aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    Selective vulnerability of the ventral hippocampus-prelimbic cortex axis parvalbumin interneuron network underlies learning deficits of fragile X mice
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    sciencedirect.com/science/article/pii/S2211124724004522
  6. Apr 2024
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    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
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    Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons
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    sciencedirect.com/science/article/pii/S0896627324001673
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
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    sciencedirect.com/science/article/pii/S0092867424002502
  10. Mar 2024
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    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    sciencedirect.com/science/article/pii/S2666379124001149
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway
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    sciencedirect.com/science/article/pii/S1534580724001424
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    PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA
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    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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    sciencedirect.com/science/article/pii/S0896627324000898
  17. Feb 2024
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    ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells
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    sciencedirect.com/science/article/pii/S2211124724001463
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    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
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    Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors
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    sciencedirect.com/science/article/pii/S2211124724000627
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    Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527942/
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    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
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    sciencedirect.com/science/article/pii/S1534580724000443
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    Specialized replication mechanisms maintain genome stability at human centromeres
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    RNF4 prevents genomic instability caused by chronic DNA under-replication
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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA combing versus DNA spreading and the separation of sister chromatids
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    Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury
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    sciencedirect.com/science/article/pii/S1074761324000323
  29. Jan 2024
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    Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
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    Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility
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    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility
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  36. Dec 2023
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    sciencedirect.com/science/article/pii/S258900422302641X
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    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
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    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723015358
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    Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala
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    Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain
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    sciencedirect.com/science/article/pii/S0092867423012333
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    Lysosomal dynamics regulate mammalian cortical neurogenesis
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    Protocol for lentivirus-mediated delivery of genes to study neurogenesis and cognitive function in adult rodents
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    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    The role of desmoplakin for neuronal function in the dentate gyrus and anxiety-related behavior
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    Microbial-dependent recruitment of immature myeloid cells promotes intestinal regeneration.
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    Divergent Recruitment of Developmentally-Defined Neuronal Ensembles Supports Memory Dynamics
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    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
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    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
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    Regional Differences in Progenitor Consumption Dynamics Shape Brain Growth during Development
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury
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    Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism
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    The splicing factor DHX38 enables retinal development through safeguarding genome integrity
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    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
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    Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer
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  62. Sep 2023
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    Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lmx1a is a master regulator of the cortical hem
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    Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice
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    Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis
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    Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells
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    Social recognition memory differences between mouse strains: On the effects of social isolation, adult neurogenesis, and environmental enrichment
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    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
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    Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process
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    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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  81. Jun 2023
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    SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex
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    Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal
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    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube
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    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
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  88. May 2023
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    In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury
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    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    DNA Combing versus DNA Spreading and the Separation of Sister Chromatids
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    Presenilin enhancer2 is critical for the transition of apical progenitors to neurons but not basal progenitors in the developing hippocampus
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    Aging impairs the essential contributions of non-glial progenitors to neurorepair in the dorsal telencephalon of the Killifish Nothobranchius furzeri
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    The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging
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    Sexually dimorphic regulation of gonadotrope cell hyperplasia in medaka pituitary via mitosis and transdifferentiation
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    PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
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    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    Cell proliferation and glial cell marker expression in the wall of the third ventricle in the tuberal region of the male mouse hypothalamus during postnatal development
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    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
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    Voluntary running exercise modifies astrocytic population and features in the peri-infarct cortex
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    D-2-hydroxyglutarate dehydrogenase governs adult neural stem cell activation and promotes histone acetylation via ATP-citrate lyase
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses
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    Increased replication origin firing links replication stress to whole chromosomal instability in human cancer
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    POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
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    POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps
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    Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors
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    Cephalopod retinal development shows vertebrate-like mechanisms of neurogenesis
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    Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
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    Metabolic regulation by p53 prevents R-loop-associated genomic instability
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    Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  137. Sep 2022
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    Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
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    Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner
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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells
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    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs
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    Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis
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    Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
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  152. Jul 2022
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    Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis
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    Sox11b regulates the migration and fate determination of... : Neural Regeneration Research
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    FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Molecular signatures and cellular diversity during mouse habenula development
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  158. Jun 2022
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    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
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    ROS Inhibits Cell Growth by Regulating 4EBP and S6K, Independent of TOR, during Development
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    BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging
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  165. May 2022
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    In vivo partial cellular reprogramming enhances liver plasticity and regeneration
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  172. Mar 2022
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    Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development
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    Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex
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    Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting
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    Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells
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    Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication
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    SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal
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    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
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  180. Feb 2022
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    A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice
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    In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
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    Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
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  184. Jan 2022
  185. www.sciencedirect.com www.sciencedirect.com
    WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
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    Adaptive differentiation promotes intestinal villus recovery
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The developmental origins of heterodonty and acrodonty as revealed by reptile dentitions
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  189. Dec 2021
  190. www.science.org www.science.org
    The developmental origins of heterodonty and acrodonty as revealed by reptile dentitions
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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    The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels
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    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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    Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models
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    Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
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    Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy
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    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
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    Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
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    Aging impairs the essential contributions of non-glial progenitors to neurorepair in the dorsal telencephalon of the Killifish Nothobranchius furzeri
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    Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegans
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    Delayed application of the haematopoietic growth factors G-CSF/SCF and FL reduces neonatal excitotoxic brain injury
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    Social Interaction Rescues Memory Deficit in an Animal Model of Alzheimer's Disease by Increasing BDNF-Dependent Hippocampal Neurogenesis
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    BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus
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    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    Pen-2 negatively regulates the differentiation of oligodendrocyte precursor cells into astrocytes in the central nervous system
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