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Aug 2025
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Fibroblast bioelectric signaling drives hair growth

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Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress

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Caveolin-1/PPARα axis suppresses T follicular helper cell response in primary Sjögren disease

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  DOI: 10.1016/j.celrep.2025.116156
  
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RNF20-mediated H2B monoubiquitination protects stalled forks from degradation and promotes fork restart

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  DOI: 10.1038/s44319-025-00497-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12331980/
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A mechano-resistance mechanism in skin adapts to terrestrial locomotion

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  DOI: 10.1016/j.cell.2025.07.012
  
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cell.com/cell/fulltext/S0092-8674(25)00801-3
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Androgen receptor–mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

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  DOI: 10.1101/gr.280224.124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12315708/
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2025.07.29.667421v1.full-html.html

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  DOI: 10.1101/2025.07.29.667421
  
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Functional role of dentate gyrus calbindin-D28K in supporting neurogenesis and emotional-social behavior relevant to antidepressant action

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sciencedirect.com/science/article/pii/S0091305725001236
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BPS Publications

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  DOI: 10.1111/bph.70137
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70137
Jul 2025
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Neurons derived from NeuroD1-expressing astrocytes transition through transit-amplifying intermediates but lack functional maturity

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1. scibot 30 Jul 2025
  
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  DOI: 10.1126/sciadv.adw9296
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12292922/
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Neurons derived from NeuroD1-expressing astrocytes transition through transit-amplifying intermediates but lack functional maturity

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  DOI: 10.1126/sciadv.adw9296
  
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science.org/doi/10.1126/sciadv.adw9296
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VIRMA-mediated m6A modification regulates forebrain formation through modulating ribosome biogenesis

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  DOI: 10.1126/sciadv.adq9643
  
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science.org/doi/10.1126/sciadv.adq9643
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OASL enhances mRNA translation and reprograms lipid metabolism to promote cancer progression

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  DOI: 10.1016/j.celrep.2025.115901
  
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sciencedirect.com/science/article/pii/S2211124725006722
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Cloche/Npas4l is a pro-regenerative platelet factor during zebrafish heart regeneration

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  DOI: 10.1016/j.devcel.2025.06.015
  
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sciencedirect.com/science/article/pii/S1534580725003703
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VIRMA-mediated m6A modification regulates forebrain formation through modulating ribosome biogenesis

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  DOI: 10.1126/sciadv.adq9643
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12204135/
Jun 2025
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Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.06.004
  
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The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.06.002
  
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sxaf033-html.html

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  DOI: 10.1093/stmcls/sxaf033
  
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52.53.155.43/d271da24f5608ba4b4a026e7ab348d3d84f6804f/sxaf033-html.html
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1-s2.0-S2589004225009605-main-html.html

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1. scibot 15 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112699
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12164204/
May 2025
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MePCE promotes homologous recombination through coordinating R-loop resolution at DNA double-stranded breaks

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115740
  
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1-s2.0-S2589004225009605-main-html.html

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  DOI: 10.1016/j.isci.2025.112699
  
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RSPO1, a potent inducer of pancreatic β cell neogenesis

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  DOI: 10.1016/j.xcrm.2025.102126
  
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sciencedirect.com/science/article/pii/S2666379125001995
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Genomic context influences translesion synthesis DNA polymerase-dependent mechanisms of micronuclei induction by G-quadruplexes

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  DOI: 10.1016/j.celrep.2025.115706
  
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Regional differences in progenitor metabolism shape brain growth during development

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  DOI: 10.1016/j.cell.2025.04.003
  
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sciencedirect.com/science/article/pii/S0092867425004052
Apr 2025
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RIF1 controls replication timing in early mouse embryos independently of lamina-associated nuclear organization

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  DOI: 10.1016/j.devcel.2025.03.016
  
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cell.com/developmental-cell/abstract/S1534-5807(25)00179-0
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Spatial regulation of glucose and lipid metabolism by hepatic insulin signaling

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  DOI: 10.1016/j.cmet.2025.03.015
  
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Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling

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  DOI: 10.1016/j.celrep.2025.115527
  
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Human neuron chimeric mice reveal impairment of DVL-1-mediated neuronal migration by sevoflurane and potential treatment by rTMS

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  DOI: 10.1038/s12276-025-01425-0
  
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link.springer.com/article/10.1038/s12276-025-01425-0
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Olfactory bulb interneurons – The developmental timeline and targeting defined by embryonic neurogenesis

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  DOI: 10.1016/j.mcn.2025.104007
  
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Mar 2025
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m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice

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  DOI: 10.1016/j.stem.2025.02.011
  
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sciencedirect.com/science/article/pii/S1934590925000797
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Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

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1. scibot 20 Mar 2025
  
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  DOI: 10.1002/advs.202410718
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202410718
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Treadmill exercise in combination with acousto-optic and... : Neural Regeneration Research

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  DOI: 10.4103/NRR.NRR-D-23-01681
  
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journals.lww.com/nrronline/fulltext/2025/09000/treadmill_exercise_in_combination_with.31.aspx
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Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development

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  DOI: 10.1016/j.celrep.2025.115384
  
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sciencedirect.com/science/article/pii/S221112472500155X
Feb 2025
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Neural stem cell relay from B1 to B2 cells in the adult mouse ventricular-subventricular zone

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  DOI: 10.1016/j.celrep.2025.115264
  
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Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease

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  DOI: 10.1101/2025.01.20.633414
  
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Microglial plasticity governed by state-specific enhancer landscapes

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A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance

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1-s2.0-S2589004225001130-main-html.html

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Interleukin-34 and debris clearance by mononuclear phagocytes drive retinal pigment epithelium regeneration in zebrafish

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Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A

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DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance

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Agarose hydrogel-mediated electroporation method for retinal tissue cultured at the air-liquid interface

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Reconstructing a new hippocampal engram for systems reconsolidation and remote memory updating

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PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress

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Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition

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Microbiota-derived short-chain fatty acids determine stem cell characteristics of gastric chief cells

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GW117 induces anxiolytic effects by improving hippocampal functions

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TLX3 regulates CGN progenitor proliferation during cerebellum development and its dysfunction can lead to autism

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Profound synthetic lethality between SMARCAL1 and FANCM

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Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer

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Acute multi-level response to defective de novo chromatin assembly in S-phase

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Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis

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Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts

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Mosaic ablation of pancreatic β cells induces de-differentiation and repetitive proliferation of residual β cells in adult mice

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Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain

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A broadly applicable method for quantifying cardiomyocyte cell division identifies proliferative events following myocardial infarction

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Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus

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RAD51 protects abasic sites to prevent replication fork breakage

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Dynamic regulation of tissue fluidity controls skin repair during wound healing

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HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

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RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes

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Protocol to establish a demyelinated animal model to study hippocampal neurogenesis and cognitive function in adult rodents

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PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair

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Distinct migratory behaviors of striosome and matrix cells underlying the mosaic formation in the developing striatum

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Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

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Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis

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The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells

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Impaired phase separation and nucleolar functions in hiPSC models of SNORD118-related ribosomopathies

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FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition

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Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

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SETDB1 regulates short interspersed nuclear elements and chromatin loop organization in mouse neural precursor cells

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Memory loss and aberrant neurogenesis in mice exposed to patient anti-N-methyl-d-aspartate receptor antibodies

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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

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2024.02.25.581951v1.full-html.html

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Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors

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Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus

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Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells

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EGF-mediated suppression of cell extrusion during mucosal damage attenuates opportunistic fungal invasion

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Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells

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Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation

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AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease

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Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

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Numb positively regulates Hedgehog signaling at the ciliary pocket

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AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer

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RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells

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PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair

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Selective vulnerability of the ventral hippocampus-prelimbic cortex axis parvalbumin interneuron network underlies learning deficits of fragile X mice

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A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation

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Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons

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The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity

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Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma

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Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape

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Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway

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PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA

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RTF2 controls replication repriming and ribonucleotide excision at the replisome

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Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression

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ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells

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A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients

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Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection

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Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety

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Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors

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Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors

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SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway

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Specialized replication mechanisms maintain genome stability at human centromeres

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RNF4 prevents genomic instability caused by chronic DNA under-replication

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DNA combing versus DNA spreading and the separation of sister chromatids

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Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury

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Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells

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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair

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Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility

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Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres

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Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility

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Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells

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A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling

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PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition

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FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination

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Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala

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Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain

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Lysosomal dynamics regulate mammalian cortical neurogenesis

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Protocol for lentivirus-mediated delivery of genes to study neurogenesis and cognitive function in adult rodents

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Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging

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53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication

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The role of desmoplakin for neuronal function in the dentate gyrus and anxiety-related behavior

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ccr-23-2005-html.html

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Microbial-dependent recruitment of immature myeloid cells promotes intestinal regeneration.

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Divergent Recruitment of Developmentally-Defined Neuronal Ensembles Supports Memory Dynamics

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Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma

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Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer

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Regional Differences in Progenitor Consumption Dynamics Shape Brain Growth during Development

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Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury

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Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism

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The splicing factor DHX38 enables retinal development through safeguarding genome integrity

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ioad134-html.html

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ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

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Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer

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Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

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can-22-3646-html.html

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Lmx1a is a master regulator of the cortical hem

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Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice

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Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis

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Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells

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Social recognition memory differences between mouse strains: On the effects of social isolation, adult neurogenesis, and environmental enrichment

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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging

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Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction

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FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress

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ioad095-html.html

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Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process

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FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth

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Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis

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Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens

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SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex

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Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal

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FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics

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Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube

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Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination

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Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability

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In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury

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Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair

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Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair

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DNA Combing versus DNA Spreading and the Separation of Sister Chromatids

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MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

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Presenilin enhancer2 is critical for the transition of apical progenitors to neurons but not basal progenitors in the developing hippocampus

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Aging impairs the essential contributions of non-glial progenitors to neurorepair in the dorsal telencephalon of the Killifish Nothobranchius furzeri

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The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging

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A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation

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Estradiol cycling drives female obesogenic adipocyte hyperplasia

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Sexually dimorphic regulation of gonadotrope cell hyperplasia in medaka pituitary via mitosis and transdifferentiation

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ATXN3 controls DNA replication and transcription by regulating chromatin structure

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PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation

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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination

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Cell proliferation and glial cell marker expression in the wall of the third ventricle in the tuberal region of the male mouse hypothalamus during postnatal development

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The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool

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Voluntary running exercise modifies astrocytic population and features in the peri-infarct cortex

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Median eminence myelin continuously turns over in adult mice

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D-2-hydroxyglutarate dehydrogenase governs adult neural stem cell activation and promotes histone acetylation via ATP-citrate lyase

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Cortical projection to the subventricular zone and its effect on adult neurogenesis in mice

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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses

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TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

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The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model

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Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice

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Increased replication origin firing links replication stress to whole chromosomal instability in human cancer

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NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors

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NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors

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Adult newborn granule cells confer emotional state–dependent adaptability in memory retrieval

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POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells

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POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps

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POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

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