168 Matching Annotations
  1. Last 7 days
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    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
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  3. Apr 2024
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    In situ direct reprogramming of astrocytes to neurons via polypyrimidine tract-binding protein 1 knockdown in a mouse model of ischemic stroke
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
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    KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
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    sciencedirect.com/science/article/pii/S1934590924000857
  8. Mar 2024
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    Matrilin-3 supports neuroprotection in ischemic stroke by suppressing astrocyte-mediated neuroinflammation
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    sciencedirect.com/science/article/pii/S2211124724003085
  10. Feb 2024
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    Sequential activity of CA1 hippocampal cells constitutes a temporal memory map for associative learning in mice
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    sciencedirect.com/science/article/abs/pii/S0960982224000216
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    Sirt6 regulates proliferation of neural precursor cells and cortical neurogenesis in mice
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  13. Jan 2024
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    A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior
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    Differential contribution of TrkB and p75NTR to BDNF-dependent self-renewal, proliferation, and differentiation of adult neural stem cells
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  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampal glial inflammatory markers are differentially altered in a novel mouse model of perimenopausal cerebral amyloid angiopathy
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    NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model
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    Comparing HD knockin pigs and mice reveals the pathological role of IL-17
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  20. Nov 2023
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    Aging Modulates the Ability of Quiescent Radial Glia-Like Stem Cells in the Hippocampal Dentate Gyrus to be Recruited into Division by Pro-neurogenic Stimuli
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    The proteomic landscape of synaptic diversity across brain regions and cell types
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  23. Oct 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway
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    Co-cultures of cerebellar slices from mice with different reelin genetic backgrounds as a model to study cortical lamination
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    Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism
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    Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice
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    Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
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      DOI: 10.7554/eLife.88279

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581688/
  29. Sep 2023
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Copper induces neuron-sparing, ferredoxin 1-independent astrocyte toxicity mediated by oxidative stress
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      DOI: 10.1111/jnc.15961

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15961
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    NAD+ rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis
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    sciencedirect.com/science/article/abs/pii/S0896627323006220
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    Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes
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      DOI: 10.1038/s41386-023-01718-w

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  33. Aug 2023
  34. www.nature.com www.nature.com
    Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model
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    LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis
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    sciencedirect.com/science/article/pii/S2211124723009865
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues
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      DOI: 10.1101/2023.07.13.548758

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    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptojanin 1 Modulates Functional Recovery After Incomplete Spinal Cord Injury in Male Apolipoprotein E Epsilon 4 Mice
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      DOI: 10.1089/neur.2023.0023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10389254/
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    Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte–Synapse Proximity and Alter Dendritic Spine Morphometrics That Are Reversed by N-Acetylcysteine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10378353/
  40. Jul 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10360083/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury
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      DOI: 10.3389/fncel.2023.1163436

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    ncbi.nlm.nih.gov/pmc/articles/PMC10321410/
  44. Jun 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced Neural Stem Cells Suppressed Neuroinflammation by Inhibiting the Microglial Pyroptotic Pathway in Intracerebral Hemorrhage Rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285565/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vasculature in the mouse colon and spatial relationships with the enteric nervous system, glia, and immune cells
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  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Roflumilast protects against spatial memory impairments and exerts anti‐inflammatory effects after transient global cerebral ischemia
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      DOI: 10.1111/ejn.15089

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    onlinelibrary.wiley.com/doi/10.1111/ejn.15089
  48. May 2023
  49. www.sciencedirect.com www.sciencedirect.com
    A living ex vivo platform for functional, personalized brain cancer diagnosis
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      DOI: 10.1016/j.xcrm.2023.101042

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    sciencedirect.com/science/article/pii/S2666379123001568
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exendin-4 and linagliptin attenuate neuroinflammation in a... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154509/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain Histology and Immunohistochemistry After Resuscitation From Hemorrhagic Shock in Swine With Pre-Existing Atherosclerosis and Sodium Thiosulfate (Na2S2O3) Treatment
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      DOI: 10.3389/fmed.2022.925433

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    ncbi.nlm.nih.gov/pmc/articles/PMC9279570/
  52. Apr 2023
  53. www.biorxiv.org www.biorxiv.org
    Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
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      DOI: 10.1101/2023.04.05.535722

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    biorxiv.org/content/10.1101/2023.04.05.535722v3
  54. 52.53.155.43 52.53.155.43
    Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury
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  55. Mar 2023
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    Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity
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  58. Feb 2023
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    PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
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    β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence
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  63. Jan 2023
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    Delayed administration of Trichilia catigua A. Juss. Ethyl-acetate fraction after cerebral ischemia prevents spatial memory deficits, decreases oxidative stress, and impacts neural plasticity in rats
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    Chemogenetic activation of astrocytes promotes remyelination and restores cognitive deficits in visceral hypersensitive rats
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  66. Dec 2022
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  68. Nov 2022
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    Terminal field volume of the glossopharyngeal nerve in adult rats reverts to prepruning size following microglia depletion with PLX5622
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    The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer’s disease
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  72. Oct 2022
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  75. Sep 2022
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  77. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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  81. Jul 2022
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  84. Jun 2022
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE
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  90. May 2022
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  92. Apr 2022
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    Selective activation of ABCA1/ApoA1 signalling in the V1 by magnetoelectric stimulation ameliorates depression via regulation of synaptic plasticity
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    Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter
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  107. Jan 2022
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    The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
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  109. Nov 2021
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    Flexible and stretchable polymer optical fibers for chronic brain and vagus nerve optogenetic stimulations in free-behaving animals
    1
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      DOI: 10.1186/s12915-021-01187-x

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    Assessment of retinal oxygen metabolism, visual function, thickness and degeneration markers after variable ischemia/reperfusion in rats
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      DOI: 10.1016/j.exer.2021.108838

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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
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      DOI: 10.7554/eLife.72034

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  113. Oct 2021
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Faim knockout leads to gliosis and late-onset neurodegeneration of photoreceptors in the mouse retina
    1
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      DOI: 10.1002/jnr.24978

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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms
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      DOI: 10.4103/1673-5374.314312

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  116. www.sciencedirect.com www.sciencedirect.com
    PUPIL enables mapping and stamping of transient electrical connectivity in developing nervous systems
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    Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy
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      DOI: 10.1016/j.isci.2021.103140

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  118. Sep 2021
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    Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis
    1
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      DOI: 10.1007/s12640-021-00417-y

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  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroimmunological complications arising from chemotherapy-induced gut toxicity and opioid exposure in female dark agouti rats
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  121. Aug 2021
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    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo
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      DOI: 10.1016/j.neuron.2016.03.016

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Surface topography during neural stem cell differentiation regulates cell migration and cell morphology
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  125. www.jneurosci.org www.jneurosci.org
    Pen-2 negatively regulates the differentiation of oligodendrocyte precursor cells into astrocytes in the central nervous system
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      DOI: 10.1523/JNEUROSCI.2455-19.2021

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  126. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Altered hippocampal kynurenine pathway metabolism contribute to hyperexcitability in human mesial temporal lobe epilepsy-hippocampal sclerosis
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      DOI: 10.1111/bph.15534

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  127. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice
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      DOI: 10.1016/j.celrep.2018.10.070

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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Surface topography during neural stem cell differentiation regulates cell migration and cell morphology. - PubMed - NCBI
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  130. Jul 2021
  131. www.sciencedirect.com www.sciencedirect.com
    Peripheral Nerve Injury Triggers Neuroinflammation in the Medial Prefrontal Cortex and Ventral Hippocampus in a Subgroup of Rats with Coincident Affective Behavioural Changes
    1
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      rabbit-anti-rat glial fibrillary acidic protein (GFAP)

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Infection Augments Expression of Mechanosensing Piezo1 Channels in Amyloid Plaque-Reactive Astrocytes
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      DOI: 10.3389/fnagi.2018.00332

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  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Parenchymal pericytes are not the major contributor of extracellular matrix in the fibrotic scar after stroke in male mice
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  134. www.sciencedirect.com www.sciencedirect.com
    Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play
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      DOI: 10.1016/j.neuron.2019.02.006

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  136. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Marine bacterial extracts as a new rich source of drugs against Alzheimer's disease
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits
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  138. www.sciencedirect.com www.sciencedirect.com
    Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Surface topography during neural stem cell differentiation regulates cell migration and cell morphology. - PubMed - NCBI
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  140. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transplantation with hypoxia‐preconditioned mesenchymal stem cells suppresses brain injury caused by cardiac arrest–induced global cerebral ischemia in rats
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      AB 305808

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  141. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Early detection of whole body radiation induced microstructural and neuroinflammatory changes in hippocampus: A diffusion tensor imaging and gene expression study
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      DOI: 10.1002/jnr.23833

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  142. www.sciencedirect.com www.sciencedirect.com
    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
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  143. link.springer.com link.springer.com
    Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages
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  144. Jun 2021
  145. www.sciencedirect.com www.sciencedirect.com
    Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms
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  146. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cerebellar spongiform degeneration is accompanied by metabolic, cellular, and motor disruption in male rats with portacaval anastomosis
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  147. May 2021
  148. www.sciencedirect.com www.sciencedirect.com
    Brain glycogen serves as a critical glucosamine cache required for protein glycosylation
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      DOI: 10.1016/j.cmet.2021.05.003

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  149. www.nature.com www.nature.com
    Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
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      Anti-GFAP

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  150. www.sciencedirect.com www.sciencedirect.com
    Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M
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      DOI: 10.1016/j.immuni.2021.01.004

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  151. Apr 2021
  152. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chemogenetic manipulation of astrocytic signaling in the basolateral amygdala reduces binge‐like alcohol consumption in male mice
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      DOI: 10.1002/jnr.24841

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  153. www.sciencedirect.com www.sciencedirect.com
    Posttraumatic learning deficits correlate with initial trauma severity and chronic cellular reactions after closed head injury in male mice
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      DOI: 10.1016/j.expneurol.2021.113721

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  154. www.sciencedirect.com www.sciencedirect.com
    Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics
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    sciencedirect.com/science/article/pii/S2211124721002564
  155. Mar 2021
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying a population of glial progenitors that have been mistaken for neurons in embryonic mouse cortical culture
    1
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      DOI: 10.1523/ENEURO.0388-20.2020

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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice
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  160. Feb 2021
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    Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling
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  164. Jan 2021
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    QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis
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  167. Nov 2020
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    Generation, establishment and characterization of a pluripotent stem cell line (CVTTHi001-A) from primary fibroblasts isolated from a patient with Activated PI3 kinase delta syndrome (APDS2)
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    SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
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  173. Sep 2020
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    Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats
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    Basolateral Amygdala Drives a GPCR-Mediated Striatal Memory Necessary for Predictive Learning to Influence Choice
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    GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function
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    Relation of Retinal Oxygen Measures to Electrophysiology and Survival Indicators after Permanent, Incomplete Ischemia in Rats
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    PCC0208009, an indirect IDO1 inhibitor, alleviates neuropathic pain and co-morbidities by regulating synaptic plasticity of ACC and amygdala
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    Mesenchymal Stem Cells Ameliorate Cuprizone-Induced Demyelination by Targeting Oxidative Stress and Mitochondrial Dysfunction
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    Spatiotemporal Distribution of Microglia After Traumatic Brain Injury in Male Mice - Henry W. Caplan, Fanni Cardenas, Franciska Gudenkauf, Pamela Zelnick, Hasen Xue, Charles S. Cox, Supinder S. Bedi, 2020
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    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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    Large 1p36 Deletions Affecting Arid1a Locus Facilitate Mycn-Driven Oncogenesis in Neuroblastoma
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    Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth
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  184. Jan 2020
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    Rat Model of Cockayne Syndrome Neurological Disease
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    Astrocytic response to neural injury is larger during development than in adulthood and is not predicated upon the presence of microglia
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    Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury
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    Epileptogenesis-Associated Alterations of Heat Shock Protein 70 in a Rat Post-Status Epilepticus Model
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    Neuroprotective effects of an engineered commensal bacterium in the 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine Parkinson disease mouse model via producing glucagon‐like peptide‐1
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    Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells
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    Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play
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    Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling
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    A new model to study cell-to-cell transfer of αSynuclein in vivo
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    3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity
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    Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor
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    α2δ-1 Signaling Drives Cell Death, Synaptogenesis, Circuit Reorganization, and Gabapentin-Mediated Neuroprotection in a Model of Insult-Induced Cortical Malformation.
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    Regulation and effects of neurotrophic factors after neural stem cell transplantation in a transgenic mouse model of Alzheimer disease
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  204. Nov 2017
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    Adult Hippocampal Neurogenesis along the Dorsoventral Axis Contributes Differentially to Environmental Enrichment Combined with Voluntary Exercise in Alleviating Chronic Inflammatory Pain in Mice
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    Cell‐ and region‐specific expression of depression‐related protein p11 (S100a10) in the brain
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    Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice
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    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo
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    Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model
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    Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway
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